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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for FOXO1 (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0001568blood vessel developmentIBA
GO:0006916anti-apoptosisIDA
GO:0006974response to DNA damage stimulusIBA
GO:0007389pattern specification processIBA
GO:0008286insulin receptor signaling pathwayIBA
GO:0008543fibroblast growth factor receptor signaling pathwayTAS
GO:0009790embryo developmentIBA
GO:0009888tissue developmentIBA
GO:0031018endocrine pancreas developmentTAS
GO:0032873negative regulation of stress-activated MAPK cascadeIDA
GO:0042127regulation of cell proliferationIBA
GO:0045722positive regulation of gluconeogenesisIEA
GO:0045893positive regulation of transcription, DNA-dependentIDA
GO:0045944positive regulation of transcription from RNA polymerase II promoterIDA
GO:0048011nerve growth factor receptor signaling pathwayTAS
GO:0048015phosphatidylinositol-mediated signalingTAS
GO:0048513organ developmentIBA
GO:0051090regulation of sequence-specific DNA binding transcription factor activityIBA
cellular_component
GO:0005634nucleusIDA
GO:0005654nucleoplasmTAS
GO:0005667transcription factor complexIBA
GO:0005737cytoplasmIDA
GO:0005829cytosolTAS
molecular_function
GO:0003690double-stranded DNA bindingIBA
GO:0003705sequence-specific distal enhancer binding RNA polymerase II transcription factor activityIBA
GO:0005515protein bindingIPI
GO:0008134transcription factor bindingIBA
GO:0008301DNA bending activityIBA
GO:0019901protein kinase bindingIBA
GO:0043565sequence-specific DNA bindingIDA

Protein-protein interaction details for FOXO1 (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
ARAffinity Capture-Westernphysical12482965
ARTwo-hybridphysical12482965
ARFar Westernphysical12482965
SMAD3Affinity Capture-Westernphysical15084259
SMAD4Affinity Capture-Westernphysical15084259
SMAD4Affinity Capture-Westernphysical15084259
CREBBPTwo-hybridphysical10973497
CREBBPReconstituted Complexphysical10973497
SRCReconstituted Complexphysical10973497
YWHAGAffinity Capture-Westernphysical11237865
YWHAZAffinity Capture-Westernphysical11237865
TSC2Affinity Capture-Westernphysical17077083
TSC2Reconstituted Complexphysical17077083
TSC2Co-localizationphysical17077083
TSC2Affinity Capture-Westernphysical17077083
ESR1Two-hybridphysical11435445
ESR1Reconstituted Complexphysical11435445
CEBPBReconstituted Complexphysical11893744
HOXA5Reconstituted Complexphysical12163409
HNF4AReconstituted Complexphysical12519792
RFWD2Affinity Capture-Westernphysical18815134
PARP1Affinity Capture-Westernphysical19281796
PARP1Affinity Capture-Westernphysical19281796
PARP1Reconstituted Complexphysical19281796
HNF4AAffinity Capture-Westernphysical19740748
HOXA11Affinity Capture-Westernphysical19727442
LRPPRCReconstituted Complexphysical17050673
SKP2Affinity Capture-Westernphysical15668399
SKP2Affinity Capture-Westernphysical15668399
UBCAffinity Capture-Westernphysical15668399
SKP2Reconstituted Complexphysical15668399
PMLAffinity Capture-Westernphysical16154098
PMLAffinity Capture-Westernphysical16154098
SIRT1Affinity Capture-Westernphysical16154098
CREBBPAffinity Capture-Westernphysical16154098
AKT1Biochemical Activityphysical16076959
UBCAffinity Capture-Westernphysical13679577
UBCReconstituted Complexphysical13679577
CREBBPAffinity Capture-Westernphysical15220471
CREBBPReconstituted Complexphysical15220471
CREBBPAffinity Capture-Westernphysical15220471
CREBBPBiochemical Activityphysical15220471
SIRT2Affinity Capture-Westernphysical15220471
SIRT2Reconstituted Complexphysical15220471
SIRT2Biochemical Activityphysical15220471
SIRT2Affinity Capture-Westernphysical20543840
ATG7Affinity Capture-Westernphysical20543840
STUB1Affinity Capture-Westernphysical19483080
UBCAffinity Capture-Westernphysical19483080
UBCAffinity Capture-Westernphysical17210752
SKP2Affinity Capture-Westernphysical19686743
UBCAffinity Capture-Westernphysical19686743
NLKAffinity Capture-Westernphysical20874444
MDM2Affinity Capture-Westernphysical19321440
MDM2Affinity Capture-Westernphysical19321440
MDM2Reconstituted Complexphysical19321440
UBCAffinity Capture-Westernphysical19321440
ESR1Two-hybridphysical11353774
ESR1Reconstituted Complexphysical11353774
RARAReconstituted Complexphysical11353774
TXNRD1Reconstituted Complexphysical11353774