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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for FOXO3 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000122 negative regulation of transcription from RNA polymerase II promoter IMP GO:0001542 ovulation from ovarian follicle IBA GO:0001542 ovulation from ovarian follicle IEA GO:0001544 initiation of primordial ovarian follicle growth IBA GO:0001544 initiation of primordial ovarian follicle growth IEA GO:0001547 antral ovarian follicle growth IBA GO:0001547 antral ovarian follicle growth IEA GO:0001556 oocyte maturation IBA GO:0001556 oocyte maturation IEA GO:0006351 transcription, DNA-dependent IDA GO:0006915 apoptosis IDA GO:0006917 induction of apoptosis IBA GO:0006917 induction of apoptosis IEA GO:0006974 response to DNA damage stimulus IBA GO:0007389 pattern specification process IBA GO:0008286 insulin receptor signaling pathway IBA GO:0008543 fibroblast growth factor receptor signaling pathway TAS GO:0009790 embryo development IBA GO:0009888 tissue development IBA GO:0030330 DNA damage response, signal transduction by p53 class mediator IEA GO:0042127 regulation of cell proliferation IBA GO:0042593 glucose homeostasis IBA GO:0042593 glucose homeostasis IEA GO:0045648 positive regulation of erythrocyte differentiation IDA GO:0045893 positive regulation of transcription, DNA-dependent IDA GO:0045893 positive regulation of transcription, DNA-dependent IEA GO:0045944 positive regulation of transcription from RNA polymerase II promoter IDA GO:0048011 nerve growth factor receptor signaling pathway TAS GO:0048015 phosphatidylinositol-mediated signaling TAS GO:0051090 regulation of sequence-specific DNA binding transcription factor activity IBA cellular_component GO:0005624 membrane fraction IEA GO:0005634 nucleus IDA GO:0005634 nucleus IEA GO:0005654 nucleoplasm TAS GO:0005667 transcription factor complex IBA GO:0005737 cytoplasm IDA GO:0005737 cytoplasm IEA GO:0005829 cytosol IBA GO:0005829 cytosol IEA molecular_function GO:0003690 double-stranded DNA binding IBA GO:0003700 sequence-specific DNA binding transcription factor activity IDA GO:0003700 sequence-specific DNA binding transcription factor activity IEA GO:0003705 sequence-specific distal enhancer binding RNA polymerase II transcription factor activity IBA GO:0005515 protein binding IPI GO:0008134 transcription factor binding IBA GO:0008301 DNA bending activity IBA GO:0019901 protein kinase binding IPI GO:0043565 sequence-specific DNA binding IDA GO:0043565 sequence-specific DNA binding IEA

Protein-protein interaction details for FOXO3 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID SMAD3 Affinity Capture-Western physical 15084259 SMAD4 Affinity Capture-Western physical 15084259 SMAD4 Affinity Capture-Western physical 15084259 YWHAZ Affinity Capture-Western physical 10102273 USP7 Affinity Capture-Western physical 16964248 C12orf44 Affinity Capture-MS physical 20562859 YWHAE Affinity Capture-MS physical 20562859 YWHAH Affinity Capture-MS physical 20562859 YWHAB Affinity Capture-MS physical 20562859 PGK1 Affinity Capture-MS physical 20562859 FKBP4 Affinity Capture-MS physical 20562859 GBAS Affinity Capture-MS physical 20562859 CTNNB1 Affinity Capture-Western physical 15905404 CTNNB1 Affinity Capture-Western physical 15905404 SIRT3 Affinity Capture-Western physical 18781224 MYC Affinity Capture-Western physical 18393360 H2AFX Affinity Capture-Western physical 18344987 BRCA1 Affinity Capture-Western physical 18344987 RAD17 Affinity Capture-Western physical 18344987 ATM Affinity Capture-Western physical 18344987 ATM Affinity Capture-Western physical 18344987 H2AFX Affinity Capture-Western physical 18344987 ATM Reconstituted Complex physical 18344987 SIRT1 Affinity Capture-Western physical 15126506 SIRT1 Affinity Capture-Western physical 15126506 CREBBP Affinity Capture-Western physical 15126506 FANCD2 Affinity Capture-Western physical 20040763 FANCD2 Affinity Capture-Western physical 20040763 STK4 Affinity Capture-Western physical 21715626 SMAD1 Affinity Capture-Western physical 17289590 EP300 Affinity Capture-Western physical 19592618 EP300 Affinity Capture-Western physical 19592618 VDR Affinity Capture-Western physical 20733005 VDR Affinity Capture-Western physical 20733005 SIRT1 Affinity Capture-Western physical 20733005 VDR Reconstituted Complex physical 20733005 SIRT1 Affinity Capture-Western physical 20733005 NLK Affinity Capture-Western physical 20874444 NR1H2 Two-hybrid physical 15604093 NR1H3 Two-hybrid physical 15604093 MDM2 Affinity Capture-Western physical 19321440 MDM2 Affinity Capture-Western physical 19321440 UBC Affinity Capture-Western physical 19321440 MAPK6 Two-hybrid physical 21900206 UBC Affinity Capture-Western physical 21841822 SKP2 Affinity Capture-Western physical 21841822 UBC Reconstituted Complex physical 21841822 SKP2 Biochemical Activity physical 21841822