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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for FLT4 (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0001945lymph vessel developmentIEA
GO:0002040sprouting angiogenesisISS
GO:0006468protein phosphorylationIEA
GO:0007169transmembrane receptor protein tyrosine kinase signaling pathwayTAS
GO:0008284positive regulation of cell proliferationIEA
GO:0008284positive regulation of cell proliferationIGI
GO:0030307positive regulation of cell growthIEA
GO:0048010vascular endothelial growth factor receptor signaling pathwayIDA
GO:0048010vascular endothelial growth factor receptor signaling pathwayIGI
GO:0048010vascular endothelial growth factor receptor signaling pathwayTAS
GO:0048514blood vessel morphogenesisISS
GO:0060312regulation of blood vessel remodelingISS
cellular_component
GO:0005886plasma membraneTAS
GO:0005887integral to plasma membraneIEA
GO:0016020membraneIEA
molecular_function
GO:0000166nucleotide bindingIEA
GO:0004713protein tyrosine kinase activityIEA
GO:0004714transmembrane receptor protein tyrosine kinase activityTAS
GO:0004872receptor activityIEA
GO:0005021vascular endothelial growth factor-activated receptor activityIDA
GO:0005021vascular endothelial growth factor-activated receptor activityIEA
GO:0005515protein bindingIPI
GO:0005524ATP bindingIEA
GO:0016772transferase activity, transferring phosphorus-containing groupsIEA
GO:0019838growth factor bindingIEA
GO:0019903protein phosphatase bindingIPI

Protein-protein interaction details for FLT4 (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
VEGFCAffinity Capture-Westernphysical8700872
SHC1Reconstituted Complexphysical7970715
GRB2Reconstituted Complexphysical7970715
SHC1Affinity Capture-Westernphysical7970715
ITGB1Affinity Capture-Westernphysical11553610
SHC1Affinity Capture-Westernphysical9927207
SHC1Affinity Capture-Westernphysical8662748
SHC1Reconstituted Complexphysical8662748
IKBKGReconstituted Complexphysical20098747