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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for HEY2 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000122 negative regulation of transcription from RNA polymerase II promoter IDA GO:0000122 negative regulation of transcription from RNA polymerase II promoter IMP GO:0001570 vasculogenesis IEA GO:0003208 cardiac ventricle morphogenesis ISS GO:0006351 transcription, DNA-dependent IDA GO:0006355 regulation of transcription, DNA-dependent IEA GO:0007219 Notch signaling pathway ISS GO:0007389 pattern specification process IEA GO:0010629 negative regulation of gene expression IEA GO:0010629 negative regulation of gene expression ISS GO:0045746 negative regulation of Notch signaling pathway IEA GO:0045892 negative regulation of transcription, DNA-dependent IDA GO:0051145 smooth muscle cell differentiation NAS GO:0055015 ventricular cardiac muscle cell development IEA GO:0055015 ventricular cardiac muscle cell development ISS GO:0060045 positive regulation of cardiac muscle cell proliferation IEA GO:0060633 negative regulation of transcription initiation from RNA polymerase II promoter IDA GO:0090102 cochlea development IEA GO:0097084 vascular smooth muscle cell development IEP GO:2000678 negative regulation of transcription regulatory region DNA binding IDA GO:2000678 negative regulation of transcription regulatory region DNA binding IEA cellular_component GO:0005634 nucleus IEA GO:0005634 nucleus ISS GO:0005737 cytoplasm ISS GO:0016580 Sin3 complex IDA GO:0017053 transcriptional repressor complex IDA molecular_function GO:0000983 RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity ISS GO:0000988 protein binding transcription factor activity IDA GO:0001102 RNA polymerase II activating transcription factor binding IPI GO:0003677 DNA binding IEA GO:0003700 sequence-specific DNA binding transcription factor activity IDA GO:0005515 protein binding IPI GO:0008134 transcription factor binding NAS GO:0035939 microsatellite binding IDA GO:0042826 histone deacetylase binding IPI GO:0043565 sequence-specific DNA binding IDA

Protein-protein interaction details for HEY2 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID PLSCR1 Two-hybrid physical 16189514 SIRT1 Affinity Capture-Western physical 12535671 SIRT1 Reconstituted Complex physical 12535671 HAND1 Reconstituted Complex physical 10924525 HDAC9 Affinity Capture-Western physical 11486045 NCOR1 Affinity Capture-Western physical 11486045 SIN3A Affinity Capture-Western physical 11486045 NCOR1 Reconstituted Complex physical 11486045 HDAC1 Reconstituted Complex physical 11486045 HES1 Reconstituted Complex physical 11486045 CASP3 Affinity Capture-Western physical 17217622 BTRC Affinity Capture-Western physical 17217622