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Gene
Protein
Transcript
Promoter
Expression
GO/PPI
PubMed
Cross reference
Gene Ontology information for Bmp4 (
Rattus norvegicus
)
(Information is obtained from AmiGO)
ID
Term
Evidence
biological_process
GO:0000122
negative regulation of transcription from RNA polymerase II promoter
ISO
GO:0000186
activation of MAPKK activity
ISO
GO:0000186
activation of MAPKK activity
ISS
GO:0001501
skeletal system development
ISO
GO:0001525
angiogenesis
IEA
GO:0001525
angiogenesis
ISO
GO:0001541
ovarian follicle development
IMP
GO:0001568
blood vessel development
IEA
GO:0001568
blood vessel development
ISO
GO:0001649
osteoblast differentiation
ISO
GO:0001649
osteoblast differentiation
ISS
GO:0001654
eye development
ISO
GO:0001656
metanephros development
ISO
GO:0001657
ureteric bud development
ISO
GO:0001658
branching involved in ureteric bud morphogenesis
ISO
GO:0001658
branching involved in ureteric bud morphogenesis
ISS
GO:0001707
mesoderm formation
ISO
GO:0001759
organ induction
IEA
GO:0001759
organ induction
ISO
GO:0001822
kidney development
ISO
GO:0001822
kidney development
ISS
GO:0001823
mesonephros development
ISO
GO:0001823
mesonephros development
ISS
GO:0001843
neural tube closure
IEA
GO:0001843
neural tube closure
ISO
GO:0001934
positive regulation of protein phosphorylation
ISO
GO:0001938
positive regulation of endothelial cell proliferation
ISO
GO:0001938
positive regulation of endothelial cell proliferation
ISS
GO:0001944
vasculature development
ISO
GO:0002043
blood vessel endothelial cell proliferation involved in sprouting angiogenesis
ISO
GO:0002043
blood vessel endothelial cell proliferation involved in sprouting angiogenesis
ISS
GO:0002244
hemopoietic progenitor cell differentiation
ISO
GO:0002244
hemopoietic progenitor cell differentiation
ISS
GO:0002320
lymphoid progenitor cell differentiation
ISO
GO:0002320
lymphoid progenitor cell differentiation
ISS
GO:0003014
renal system process
IEA
GO:0003014
renal system process
ISO
GO:0003130
BMP signaling pathway involved in heart induction
IEA
GO:0003130
BMP signaling pathway involved in heart induction
ISO
GO:0003139
secondary heart field specification
IEA
GO:0003139
secondary heart field specification
ISO
GO:0003337
mesenchymal to epithelial transition involved in metanephros morphogenesis
ISO
GO:0003337
mesenchymal to epithelial transition involved in metanephros morphogenesis
ISS
GO:0007224
smoothened signaling pathway
ISO
GO:0007281
germ cell development
IEA
GO:0007281
germ cell development
ISO
GO:0007420
brain development
IEP
GO:0007498
mesoderm development
NAS
GO:0007500
mesodermal cell fate determination
IEA
GO:0007500
mesodermal cell fate determination
ISO
GO:0007507
heart development
IEA
GO:0007507
heart development
ISO
GO:0008283
cell proliferation
NAS
GO:0008284
positive regulation of cell proliferation
IMP
GO:0008284
positive regulation of cell proliferation
ISO
GO:0008285
negative regulation of cell proliferation
ISO
GO:0009612
response to mechanical stimulus
IEP
GO:0009791
post-embryonic development
IEA
GO:0009791
post-embryonic development
ISO
GO:0009888
tissue development
ISO
GO:0009948
anterior/posterior axis specification
IEA
GO:0009948
anterior/posterior axis specification
ISO
GO:0010159
specification of organ position
IEA
GO:0010159
specification of organ position
ISO
GO:0010468
regulation of gene expression
ISO
GO:0010595
positive regulation of endothelial cell migration
IEA
GO:0010595
positive regulation of endothelial cell migration
ISO
GO:0010595
positive regulation of endothelial cell migration
ISS
GO:0010628
positive regulation of gene expression
ISO
GO:0010629
negative regulation of gene expression
ISO
GO:0010862
positive regulation of pathway-restricted SMAD protein phosphorylation
IEA
GO:0010862
positive regulation of pathway-restricted SMAD protein phosphorylation
ISO
GO:0010862
positive regulation of pathway-restricted SMAD protein phosphorylation
ISS
GO:0010942
positive regulation of cell death
IEA
GO:0010942
positive regulation of cell death
ISO
GO:0014070
response to organic cyclic compound
IEP
GO:0021537
telencephalon development
ISO
GO:0021904
dorsal/ventral neural tube patterning
IEA
GO:0021904
dorsal/ventral neural tube patterning
ISO
GO:0021978
telencephalon regionalization
IEA
GO:0021978
telencephalon regionalization
ISO
GO:0021983
pituitary gland development
IEA
GO:0021983
pituitary gland development
ISO
GO:0030218
erythrocyte differentiation
IEA
GO:0030218
erythrocyte differentiation
ISO
GO:0030324
lung development
ISO
GO:0030326
embryonic limb morphogenesis
ISO
GO:0030501
positive regulation of bone mineralization
IEA
GO:0030501
positive regulation of bone mineralization
ISO
GO:0030501
positive regulation of bone mineralization
ISS
GO:0030509
BMP signaling pathway
ISO
GO:0030509
BMP signaling pathway
ISS
GO:0030900
forebrain development
ISO
GO:0032331
negative regulation of chondrocyte differentiation
IEA
GO:0032331
negative regulation of chondrocyte differentiation
ISO
GO:0032355
response to estradiol stimulus
IEP
GO:0032526
response to retinoic acid
IEP
GO:0032967
positive regulation of collagen biosynthetic process
IEA
GO:0032967
positive regulation of collagen biosynthetic process
ISO
GO:0032967
positive regulation of collagen biosynthetic process
ISS
GO:0033085
negative regulation of T cell differentiation in thymus
ISO
GO:0033088
negative regulation of immature T cell proliferation in thymus
IEA
GO:0033088
negative regulation of immature T cell proliferation in thymus
ISO
GO:0033088
negative regulation of immature T cell proliferation in thymus
ISS
GO:0034504
protein localization to nucleus
IEA
GO:0034504
protein localization to nucleus
ISO
GO:0034504
protein localization to nucleus
ISS
GO:0035116
embryonic hindlimb morphogenesis
IEA
GO:0035116
embryonic hindlimb morphogenesis
ISO
GO:0040007
growth
IEA
GO:0042326
negative regulation of phosphorylation
IEA
GO:0042326
negative regulation of phosphorylation
ISO
GO:0042326
negative regulation of phosphorylation
ISS
GO:0042475
odontogenesis of dentine-containing tooth
IEA
GO:0042475
odontogenesis of dentine-containing tooth
ISO
GO:0042476
odontogenesis
IEP
GO:0042476
odontogenesis
ISO
GO:0042476
odontogenesis
ISS
GO:0042487
regulation of odontogenesis of dentine-containing tooth
ISO
GO:0042733
embryonic digit morphogenesis
ISO
GO:0043010
camera-type eye development
ISO
GO:0043065
positive regulation of apoptosis
IEA
GO:0043065
positive regulation of apoptosis
ISO
GO:0043065
positive regulation of apoptosis
ISS
GO:0043066
negative regulation of apoptosis
IEA
GO:0043066
negative regulation of apoptosis
ISO
GO:0043066
negative regulation of apoptosis
ISS
GO:0043401
steroid hormone mediated signaling pathway
IEA
GO:0043401
steroid hormone mediated signaling pathway
ISO
GO:0043401
steroid hormone mediated signaling pathway
ISS
GO:0043407
negative regulation of MAP kinase activity
IEA
GO:0043407
negative regulation of MAP kinase activity
ISO
GO:0043407
negative regulation of MAP kinase activity
ISS
GO:0043587
tongue morphogenesis
IEP
GO:0045165
cell fate commitment
ISO
GO:0045595
regulation of cell differentiation
IDA
GO:0045595
regulation of cell differentiation
ISO
GO:0045597
positive regulation of cell differentiation
ISO
GO:0045603
positive regulation of endothelial cell differentiation
IEA
GO:0045662
negative regulation of myoblast differentiation
IEA
GO:0045662
negative regulation of myoblast differentiation
ISO
GO:0045666
positive regulation of neuron differentiation
IEA
GO:0045666
positive regulation of neuron differentiation
ISO
GO:0045669
positive regulation of osteoblast differentiation
IDA
GO:0045669
positive regulation of osteoblast differentiation
IEA
GO:0045669
positive regulation of osteoblast differentiation
IMP
GO:0045669
positive regulation of osteoblast differentiation
ISO
GO:0045669
positive regulation of osteoblast differentiation
ISS
GO:0045778
positive regulation of ossification
IDA
GO:0045778
positive regulation of ossification
IMP
GO:0045778
positive regulation of ossification
ISO
GO:0045786
negative regulation of cell cycle
ISO
GO:0045786
negative regulation of cell cycle
ISS
GO:0045839
negative regulation of mitosis
IEA
GO:0045839
negative regulation of mitosis
ISO
GO:0045839
negative regulation of mitosis
ISS
GO:0045843
negative regulation of striated muscle tissue development
IEA
GO:0045843
negative regulation of striated muscle tissue development
ISO
GO:0045892
negative regulation of transcription, DNA-dependent
IEA
GO:0045892
negative regulation of transcription, DNA-dependent
ISO
GO:0045892
negative regulation of transcription, DNA-dependent
ISS
GO:0045893
positive regulation of transcription, DNA-dependent
ISO
GO:0045893
positive regulation of transcription, DNA-dependent
ISS
GO:0045944
positive regulation of transcription from RNA polymerase II promoter
IDA
GO:0045944
positive regulation of transcription from RNA polymerase II promoter
IEA
GO:0045944
positive regulation of transcription from RNA polymerase II promoter
ISO
GO:0048286
lung alveolus development
IEA
GO:0048286
lung alveolus development
ISO
GO:0048333
mesodermal cell differentiation
ISO
GO:0048392
intermediate mesodermal cell differentiation
IEA
GO:0048392
intermediate mesodermal cell differentiation
ISO
GO:0048392
intermediate mesodermal cell differentiation
ISS
GO:0048593
camera-type eye morphogenesis
IEA
GO:0048593
camera-type eye morphogenesis
ISO
GO:0048598
embryonic morphogenesis
IEA
GO:0048598
embryonic morphogenesis
ISO
GO:0048646
anatomical structure formation involved in morphogenesis
ISO
GO:0048660
regulation of smooth muscle cell proliferation
ISO
GO:0048661
positive regulation of smooth muscle cell proliferation
IEA
GO:0048661
positive regulation of smooth muscle cell proliferation
ISO
GO:0048661
positive regulation of smooth muscle cell proliferation
ISS
GO:0048663
neuron fate commitment
IEA
GO:0048663
neuron fate commitment
ISO
GO:0048701
embryonic cranial skeleton morphogenesis
IEA
GO:0048701
embryonic cranial skeleton morphogenesis
ISO
GO:0048704
embryonic skeletal system morphogenesis
ISO
GO:0048706
embryonic skeletal system development
ISO
GO:0048715
negative regulation of oligodendrocyte differentiation
IMP
GO:0048745
smooth muscle tissue development
IEA
GO:0048745
smooth muscle tissue development
ISO
GO:0048745
smooth muscle tissue development
ISS
GO:0048754
branching morphogenesis of a tube
ISO
GO:0048754
branching morphogenesis of a tube
ISS
GO:0050680
negative regulation of epithelial cell proliferation
IEA
GO:0050680
negative regulation of epithelial cell proliferation
ISO
GO:0050918
positive chemotaxis
ISO
GO:0050918
positive chemotaxis
ISS
GO:0051145
smooth muscle cell differentiation
ISO
GO:0051150
regulation of smooth muscle cell differentiation
IEA
GO:0051150
regulation of smooth muscle cell differentiation
ISO
GO:0051384
response to glucocorticoid stimulus
IEP
GO:0055020
positive regulation of cardiac muscle fiber development
IEA
GO:0055020
positive regulation of cardiac muscle fiber development
ISO
GO:0060041
retina development in camera-type eye
IEP
GO:0060113
inner ear receptor cell differentiation
IEA
GO:0060113
inner ear receptor cell differentiation
ISO
GO:0060197
cloacal septation
IEA
GO:0060235
lens induction in camera-type eye
IEA
GO:0060235
lens induction in camera-type eye
ISO
GO:0060272
embryonic skeletal joint morphogenesis
IEA
GO:0060272
embryonic skeletal joint morphogenesis
ISO
GO:0060348
bone development
IEA
GO:0060348
bone development
ISO
GO:0060363
cranial suture morphogenesis
IEA
GO:0060363
cranial suture morphogenesis
ISO
GO:0060391
positive regulation of SMAD protein import into nucleus
IEA
GO:0060391
positive regulation of SMAD protein import into nucleus
ISO
GO:0060391
positive regulation of SMAD protein import into nucleus
ISS
GO:0060393
regulation of pathway-restricted SMAD protein phosphorylation
ISO
GO:0060393
regulation of pathway-restricted SMAD protein phosphorylation
ISS
GO:0060395
SMAD protein signal transduction
IEA
GO:0060395
SMAD protein signal transduction
ISO
GO:0060395
SMAD protein signal transduction
ISS
GO:0060425
lung morphogenesis
ISO
GO:0060429
epithelium development
IEA
GO:0060429
epithelium development
ISO
GO:0060433
bronchus development
IEA
GO:0060433
bronchus development
ISO
GO:0060438
trachea development
IEA
GO:0060438
trachea development
ISO
GO:0060440
trachea formation
IEA
GO:0060440
trachea formation
ISO
GO:0060441
epithelial tube branching involved in lung morphogenesis
IEP
GO:0060441
epithelial tube branching involved in lung morphogenesis
ISO
GO:0060442
branching involved in prostate gland morphogenesis
ISO
GO:0060449
bud elongation involved in lung branching
IEA
GO:0060449
bud elongation involved in lung branching
ISO
GO:0060502
epithelial cell proliferation involved in lung morphogenesis
IEA
GO:0060502
epithelial cell proliferation involved in lung morphogenesis
ISO
GO:0060503
bud dilation involved in lung branching
IEA
GO:0060503
bud dilation involved in lung branching
ISO
GO:0060512
prostate gland morphogenesis
IEA
GO:0060512
prostate gland morphogenesis
ISO
GO:0060548
negative regulation of cell death
IEA
GO:0060548
negative regulation of cell death
ISO
GO:0060548
negative regulation of cell death
ISS
GO:0060592
mammary gland formation
IEA
GO:0060592
mammary gland formation
ISO
GO:0060684
epithelial-mesenchymal cell signaling
IEA
GO:0060684
epithelial-mesenchymal cell signaling
ISO
GO:0060686
negative regulation of prostatic bud formation
IEA
GO:0060686
negative regulation of prostatic bud formation
ISO
GO:0060687
regulation of branching involved in prostate gland morphogenesis
IEA
GO:0060687
regulation of branching involved in prostate gland morphogenesis
ISO
GO:0060688
regulation of morphogenesis of a branching structure
ISO
GO:0061036
positive regulation of cartilage development
IEA
GO:0061036
positive regulation of cartilage development
ISO
GO:0061047
positive regulation of branching involved in lung morphogenesis
IEA
GO:0061047
positive regulation of branching involved in lung morphogenesis
ISO
GO:0061047
positive regulation of branching involved in lung morphogenesis
ISS
GO:0061149
BMP signaling pathway involved in ureter morphogenesis
IEA
GO:0061149
BMP signaling pathway involved in ureter morphogenesis
ISO
GO:0061149
BMP signaling pathway involved in ureter morphogenesis
ISS
GO:0061151
BMP signaling pathway involved in renal system segmentation
IEA
GO:0061151
BMP signaling pathway involved in renal system segmentation
ISO
GO:0061151
BMP signaling pathway involved in renal system segmentation
ISS
GO:0061155
pulmonary artery endothelial tube morphogenesis
IEA
GO:0061155
pulmonary artery endothelial tube morphogenesis
ISO
GO:0061155
pulmonary artery endothelial tube morphogenesis
ISS
GO:0070244
negative regulation of thymocyte apoptosis
IEA
GO:0070244
negative regulation of thymocyte apoptosis
ISO
GO:0070244
negative regulation of thymocyte apoptosis
ISS
GO:0070374
positive regulation of ERK1 and ERK2 cascade
IEA
GO:0070374
positive regulation of ERK1 and ERK2 cascade
ISO
GO:0071363
cellular response to growth factor stimulus
IEA
GO:0071363
cellular response to growth factor stimulus
ISO
GO:0071549
cellular response to dexamethasone stimulus
IDA
GO:0071893
BMP signaling pathway involved in nephric duct formation
IEA
GO:0071893
BMP signaling pathway involved in nephric duct formation
ISO
GO:0071893
BMP signaling pathway involved in nephric duct formation
ISS
GO:0072001
renal system development
ISO
GO:0072015
glomerular visceral epithelial cell development
IEA
GO:0072097
negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway
IEA
GO:0072097
negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway
ISO
GO:0072097
negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway
ISS
GO:0072101
specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway
IEA
GO:0072101
specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway
ISO
GO:0072101
specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway
ISS
GO:0072104
glomerular capillary formation
IEA
GO:0072104
glomerular capillary formation
ISO
GO:0072104
glomerular capillary formation
ISS
GO:0072125
negative regulation of glomerular mesangial cell proliferation
IEA
GO:0072125
negative regulation of glomerular mesangial cell proliferation
ISO
GO:0072125
negative regulation of glomerular mesangial cell proliferation
ISS
GO:0072138
mesenchymal cell proliferation involved in ureteric bud development
IEA
GO:0072161
mesenchymal cell differentiation involved in kidney development
ISO
GO:0072192
ureter epithelial cell differentiation
IEA
GO:0072192
ureter epithelial cell differentiation
ISO
GO:0072192
ureter epithelial cell differentiation
ISS
GO:0072193
ureter smooth muscle cell differentiation
IEA
GO:0072193
ureter smooth muscle cell differentiation
ISO
GO:0072193
ureter smooth muscle cell differentiation
ISS
GO:0072198
mesenchymal cell proliferation involved in ureter development
IEA
GO:0072200
negative regulation of mesenchymal cell proliferation involved in ureter development
ISO
GO:0072200
negative regulation of mesenchymal cell proliferation involved in ureter development
ISS
GO:0072205
metanephric collecting duct development
IEA
GO:0072205
metanephric collecting duct development
ISO
GO:0072205
metanephric collecting duct development
ISS
GO:0090184
positive regulation of kidney development
IEA
GO:0090184
positive regulation of kidney development
ISO
GO:0090184
positive regulation of kidney development
ISS
GO:0090190
positive regulation of branching involved in ureteric bud morphogenesis
IMP
GO:0090191
negative regulation of branching involved in ureteric bud morphogenesis
IEA
GO:0090191
negative regulation of branching involved in ureteric bud morphogenesis
ISO
GO:0090191
negative regulation of branching involved in ureteric bud morphogenesis
ISS
GO:0090194
negative regulation of glomerulus development
IEA
GO:0090194
negative regulation of glomerulus development
ISO
GO:0090194
negative regulation of glomerulus development
ISS
GO:2000005
negative regulation of metanephric S-shaped body morphogenesis
IEA
GO:2000005
negative regulation of metanephric S-shaped body morphogenesis
ISO
GO:2000005
negative regulation of metanephric S-shaped body morphogenesis
ISS
GO:2000007
negative regulation of metanephric comma-shaped body morphogenesis
IEA
GO:2000007
negative regulation of metanephric comma-shaped body morphogenesis
ISO
GO:2000007
negative regulation of metanephric comma-shaped body morphogenesis
ISS
GO:2000137
negative regulation of cell proliferation involved in heart morphogenesis
IEA
GO:2000137
negative regulation of cell proliferation involved in heart morphogenesis
ISO
cellular_component
GO:0005576
extracellular region
IEA
GO:0005576
extracellular region
ISO
GO:0005578
proteinaceous extracellular matrix
IEA
GO:0005615
extracellular space
IDA
GO:0005615
extracellular space
ISO
GO:0005737
cytoplasm
IDA
GO:0031988
membrane-bounded vesicle
IDA
molecular_function
GO:0005125
cytokine activity
IEA
GO:0005125
cytokine activity
ISO
GO:0008083
growth factor activity
IDA
GO:0008083
growth factor activity
IEA
GO:0008201
heparin binding
IEA
GO:0008201
heparin binding
ISO
GO:0042056
chemoattractant activity
IEA
GO:0042056
chemoattractant activity
ISO
GO:0042056
chemoattractant activity
ISS
GO:0042803
protein homodimerization activity
IDA
GO:0070700
BMP receptor binding
IEA
GO:0070700
BMP receptor binding
ISO
Protein-protein interaction details for Bmp4 (
Rattus norvegicus
)
(Information is obtained from BioGRID)
Not available