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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for SPDEF (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0000122negative regulation of transcription from RNA polymerase II promoterIDA
GO:0007275multicellular organismal developmentTAS
GO:0008634negative regulation of survival gene product expressionIDA
GO:0010454negative regulation of cell fate commitmentIEA
GO:0010455positive regulation of cell fate commitmentIEA
GO:0043065positive regulation of apoptosisIDA
GO:0045944positive regulation of transcription from RNA polymerase II promoterIEA
GO:0060480lung goblet cell differentiationIEA
GO:0060576intestinal epithelial cell developmentIEA
cellular_component
GO:0005634nucleusIEA
molecular_function
GO:0003700sequence-specific DNA binding transcription factor activityIEA
GO:0043565sequence-specific DNA bindingIEA

Protein-protein interaction details for SPDEF (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
NKX3-1Affinity Capture-Westernphysical11809674
NKX3-1Two-hybridphysical11809674
ARReconstituted Complexphysical10625666
PCGF2Two-hybridphysical20211142