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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for GBA (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0005975carbohydrate metabolic processIEA
GO:0006629lipid metabolic processIEA
GO:0006665sphingolipid metabolic processIEA
GO:0006680glucosylceramide catabolic processIMP
GO:0007040lysosome organizationIEA
GO:0008219cell deathIEA
GO:0023021termination of signal transductionIMP
GO:0032715negative regulation of interleukin-6 productionIDA
GO:0035307positive regulation of protein dephosphorylationIMP
GO:0043407negative regulation of MAP kinase activityIMP
GO:0046512sphingosine biosynthetic processIMP
GO:0046513ceramide biosynthetic processIMP
GO:0050728negative regulation of inflammatory responseIC
GO:0071356cellular response to tumor necrosis factorIMP
cellular_component
GO:0005764lysosomeIEA
GO:0005765lysosomal membraneISS
GO:0016020membraneIEA
GO:0043202lysosomal lumenISS
molecular_function
GO:0003824catalytic activityIEA
GO:0004348glucosylceramidase activityIDA
GO:0004348glucosylceramidase activityIEA
GO:0005102receptor bindingISS
GO:0016798hydrolase activity, acting on glycosyl bondsIEA
GO:0043169cation bindingIEA

Protein-protein interaction details for GBA (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
UBCAffinity Capture-Westernphysical22160715
HSP90AA1Affinity Capture-Westernphysical22160715
HSPA4Affinity Capture-Westernphysical22160715
TCP1Affinity Capture-Westernphysical22160715
PARK2Affinity Capture-Westernphysical20643691
PARK2Affinity Capture-Westernphysical20643691
UBCAffinity Capture-Westernphysical20643691