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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for GCK (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0005975 carbohydrate metabolic process IEA GO:0005975 carbohydrate metabolic process TAS GO:0006096 glycolysis IEA GO:0006110 regulation of glycolysis NAS GO:0008645 hexose transport TAS GO:0010827 regulation of glucose transport TAS GO:0015758 glucose transport TAS GO:0031018 endocrine pancreas development TAS GO:0032024 positive regulation of insulin secretion IMP GO:0032869 cellular response to insulin stimulus ISS GO:0042593 glucose homeostasis IMP GO:0044320 cellular response to leptin stimulus ISS GO:0045721 negative regulation of gluconeogenesis IMP GO:0045725 positive regulation of glycogen biosynthetic process IMP GO:0050796 regulation of insulin secretion IMP GO:0051156 glucose 6-phosphate metabolic process IDA GO:0051594 detection of glucose IMP GO:0055085 transmembrane transport TAS cellular_component GO:0005654 nucleoplasm TAS GO:0005829 cytosol TAS molecular_function GO:0000166 nucleotide binding IEA GO:0004340 glucokinase activity IDA GO:0004396 hexokinase activity IEA GO:0005515 protein binding IPI GO:0005524 ATP binding IDA GO:0005524 ATP binding IEA GO:0005536 glucose binding IDA GO:0016301 kinase activity IEA GO:0016740 transferase activity IEA

Protein-protein interaction details for GCK (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID PFKFB2 Two-hybrid physical 11522786 GCKR Two-hybrid physical 10601273 PCNA Reconstituted Complex physical 20849852