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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for EIF2AK1 (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0006468protein phosphorylationIEA
GO:0006950response to stressIEA
GO:0006950response to stressIEP
GO:0008285negative regulation of cell proliferationIEA
GO:0009605response to external stimulusIEP
GO:0017148negative regulation of translationIEA
GO:0045993negative regulation of translational initiation by ironNAS
GO:0046777protein autophosphorylationISS
GO:0046986negative regulation of hemoglobin biosynthetic processISS
cellular_component
GO:0005737cytoplasmIEA
molecular_function
GO:0000166nucleotide bindingIEA
GO:0003743translation initiation factor activityIEA
GO:0004674protein serine/threonine kinase activityIEA
GO:0004694eukaryotic translation initiation factor 2alpha kinase activityIDA
GO:0005524ATP bindingIEA
GO:0020037heme bindingISS
GO:0042803protein homodimerization activityISS

Protein-protein interaction details for EIF2AK1 (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
CDC37Reconstituted Complexphysical11036079
HSP90AA1Reconstituted Complexphysical11036079
CDC37Affinity Capture-Westernphysical11036079