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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for GNAS (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0001894 tissue homeostasis IEA GO:0001958 endochondral ossification IEA GO:0006112 energy reserve metabolic process IEA GO:0006112 energy reserve metabolic process TAS GO:0006171 cAMP biosynthetic process TAS GO:0006184 GTP catabolic process IBA GO:0006184 GTP catabolic process TAS GO:0006306 DNA methylation IEA GO:0006833 water transport TAS GO:0007186 G-protein coupled receptor protein signaling pathway IEA GO:0007190 activation of adenylate cyclase activity TAS GO:0007191 activation of adenylate cyclase activity by dopamine receptor signaling pathway IBA GO:0007565 female pregnancy NAS GO:0007596 blood coagulation TAS GO:0007606 sensory perception of chemical stimulus IBA GO:0007608 sensory perception of smell TAS GO:0007610 behavior IEA GO:0009306 protein secretion NAS GO:0009791 post-embryonic development IEA GO:0030168 platelet activation TAS GO:0035116 embryonic hindlimb morphogenesis IEA GO:0035264 multicellular organism growth IEA GO:0040032 post-embryonic body morphogenesis IEA GO:0042493 response to drug IEA GO:0043588 skin development IEA GO:0045669 positive regulation of osteoblast differentiation IEA GO:0045672 positive regulation of osteoclast differentiation IEA GO:0046907 intracellular transport NAS GO:0048701 embryonic cranial skeleton morphogenesis IEA GO:0050796 regulation of insulin secretion TAS GO:0051216 cartilage development IEA GO:0055085 transmembrane transport TAS GO:0071377 cellular response to glucagon stimulus TAS GO:0071514 genetic imprinting IEA cellular_component GO:0001726 ruffle IEA GO:0005576 extracellular region NAS GO:0005622 intracellular NAS GO:0005624 membrane fraction IEA GO:0005737 cytoplasm IDA GO:0005834 heterotrimeric G-protein complex IBA GO:0005834 heterotrimeric G-protein complex TAS GO:0005886 plasma membrane IEA GO:0005886 plasma membrane TAS GO:0030133 transport vesicle IEA GO:0031224 intrinsic to membrane IDA GO:0031234 extrinsic to internal side of plasma membrane IBA GO:0031410 cytoplasmic vesicle IEA GO:0032588 trans-Golgi network membrane IDA molecular_function GO:0000166 nucleotide binding IEA GO:0003674 molecular_function ND GO:0003924 GTPase activity IBA GO:0003924 GTPase activity TAS GO:0004016 adenylate cyclase activity TAS GO:0004871 signal transducer activity IBA GO:0004871 signal transducer activity IEA GO:0005085 guanyl-nucleotide exchange factor activity TAS GO:0005525 GTP binding IEA GO:0019001 guanyl nucleotide binding IEA GO:0031683 G-protein beta/gamma-subunit complex binding IBA GO:0031852 mu-type opioid receptor binding IBA GO:0035255 ionotropic glutamate receptor binding IBA GO:0046872 metal ion binding IEA

Protein-protein interaction details for GNAS (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID FSCN1 Affinity Capture-MS physical 17353931 PAICS Affinity Capture-MS physical 17353931 RUVBL1 Affinity Capture-MS physical 17353931 SHMT2 Affinity Capture-MS physical 17353931 TTC1 Affinity Capture-Western physical 12748287 RIC8A Two-hybrid physical 12652642 RIC8A Reconstituted Complex physical 12652642 ADCY6 Phenotypic Enhancement genetic 9228084 CRHR1 Affinity Capture-Western physical 10598591 RGS2 Reconstituted Complex physical 9794454 SNX13 Reconstituted Complex physical 11729322 VIPR1 Affinity Capture-Western physical 11812005 GNAS Reconstituted Complex physical 7797570 MDM2 Affinity Capture-Western physical 18948082 UBC Affinity Capture-MS physical 16196087 CALM1 Reconstituted Complex physical 15840729 UBC Affinity Capture-Western physical 20133939 GNG2 Affinity Capture-Western physical 20133939 UBC Affinity Capture-MS physical 20639865 UBC Co-purification physical 17623298 UBC Affinity Capture-MS physical 18781797 PCK1 Affinity Capture-MS physical 21726808 UBC Affinity Capture-MS physical 21987572