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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for TNF (Bos taurus) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000060 protein import into nucleus, translocation IEA GO:0000122 negative regulation of transcription from RNA polymerase II promoter IEA GO:0000185 activation of MAPKKK activity IEA GO:0000187 activation of MAPK activity IEA GO:0002740 negative regulation of cytokine secretion involved in immune response IEA GO:0002876 positive regulation of chronic inflammatory response to antigenic stimulus IEA GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin IEA GO:0006006 glucose metabolic process IEA GO:0006916 anti-apoptosis IEA GO:0006919 activation of caspase activity IEA GO:0006927 transformed cell apoptosis IEA GO:0006954 inflammatory response IEA GO:0006959 humoral immune response IEA GO:0007275 multicellular organismal development IEA GO:0008625 induction of apoptosis via death domain receptors IEA GO:0009615 response to virus IEA GO:0009887 organ morphogenesis IEA GO:0030198 extracellular matrix organization IEA GO:0030730 sequestering of triglyceride IEA GO:0031622 positive regulation of fever generation IEA GO:0032715 negative regulation of interleukin-6 production IEA GO:0032722 positive regulation of chemokine production IEA GO:0032729 positive regulation of interferon-gamma production IEA GO:0032755 positive regulation of interleukin-6 production IEA GO:0032800 receptor biosynthetic process IEA GO:0033138 positive regulation of peptidyl-serine phosphorylation IEA GO:0033209 tumor necrosis factor-mediated signaling pathway IEA GO:0034116 positive regulation of heterotypic cell-cell adhesion IEA GO:0042127 regulation of cell proliferation IEA GO:0042346 positive regulation of NF-kappaB import into nucleus IEA GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB cascade IEA GO:0043243 positive regulation of protein complex disassembly IEA GO:0044130 negative regulation of growth of symbiont in host IEA GO:0045071 negative regulation of viral genome replication IEA GO:0045080 positive regulation of chemokine biosynthetic process IEA GO:0045429 positive regulation of nitric oxide biosynthetic process IEA GO:0045672 positive regulation of osteoclast differentiation IEA GO:0045944 positive regulation of transcription from RNA polymerase II promoter IEA GO:0045994 positive regulation of translational initiation by iron IEA GO:0046325 negative regulation of glucose import IEA GO:0046330 positive regulation of JNK cascade IEA GO:0048566 embryonic digestive tract development IEA GO:0048661 positive regulation of smooth muscle cell proliferation IEA GO:0050715 positive regulation of cytokine secretion IEA GO:0050796 regulation of insulin secretion IEA GO:0050830 defense response to Gram-positive bacterium IEA GO:0050901 leukocyte tethering or rolling IEA GO:0050995 negative regulation of lipid catabolic process IEA GO:0051023 regulation of immunoglobulin secretion IEA GO:0051044 positive regulation of membrane protein ectodomain proteolysis IEA GO:0051092 positive regulation of NF-kappaB transcription factor activity IEA GO:0051222 positive regulation of protein transport IEA GO:0051384 response to glucocorticoid stimulus IEA GO:0051533 positive regulation of NFAT protein import into nucleus IEA GO:0051798 positive regulation of hair follicle development IEA GO:0051897 positive regulation of protein kinase B signaling cascade IEA GO:0060555 induction of necroptosis by extracellular signals IEA GO:0060557 positive regulation of vitamin D biosynthetic process IEA GO:0060559 positive regulation of calcidiol 1-monooxygenase activity IEA GO:0060664 epithelial cell proliferation involved in salivary gland morphogenesis IEA GO:0060693 regulation of branching involved in salivary gland morphogenesis IEA GO:0061048 negative regulation of branching involved in lung morphogenesis IEA GO:0070265 necrotic cell death IEA GO:0071230 cellular response to amino acid stimulus IEA GO:0071316 cellular response to nicotine IEA GO:0071803 positive regulation of podosome assembly IEA cellular_component GO:0001891 phagocytic cup IEA GO:0005576 extracellular region IEA GO:0005615 extracellular space IEA GO:0005622 intracellular IEA GO:0005886 plasma membrane IEA GO:0005887 integral to plasma membrane IEA GO:0009897 external side of plasma membrane IEA GO:0045121 membrane raft IEA GO:0055037 recycling endosome IEA molecular_function GO:0002020 protease binding IEA GO:0005125 cytokine activity IEA GO:0005164 tumor necrosis factor receptor binding IEA GO:0042802 identical protein binding IEA GO:0044212 transcription regulatory region DNA binding IEA

Protein-protein interaction details for TNF (Bos taurus) (Information is obtained from BioGRID)

Not available