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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for TLR4 (Bos taurus) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000187 activation of MAPK activity IEA GO:0002218 activation of innate immune response IEA GO:0002537 nitric oxide production involved in inflammatory response IEA GO:0006954 inflammatory response IEA GO:0007165 signal transduction IEA GO:0007252 I-kappaB phosphorylation IEA GO:0009617 response to bacterium IEA GO:0010572 positive regulation of platelet activation IEA GO:0030890 positive regulation of B cell proliferation IEA GO:0031663 lipopolysaccharide-mediated signaling pathway ISS GO:0032497 detection of lipopolysaccharide IEA GO:0032497 detection of lipopolysaccharide ISS GO:0032689 negative regulation of interferon-gamma production IEA GO:0032700 negative regulation of interleukin-17 production IEA GO:0032707 negative regulation of interleukin-23 production IEA GO:0032715 negative regulation of interleukin-6 production IEA GO:0032720 negative regulation of tumor necrosis factor production IEA GO:0032722 positive regulation of chemokine production IEA GO:0032727 positive regulation of interferon-alpha production IEA GO:0032728 positive regulation of interferon-beta production IEA GO:0032729 positive regulation of interferon-gamma production IEA GO:0032732 positive regulation of interleukin-1 production IEA GO:0032733 positive regulation of interleukin-10 production IEA GO:0032735 positive regulation of interleukin-12 production IEA GO:0032755 positive regulation of interleukin-6 production IEA GO:0032757 positive regulation of interleukin-8 production IEA GO:0032760 positive regulation of tumor necrosis factor production IEA GO:0042116 macrophage activation IEA GO:0042116 macrophage activation ISS GO:0042346 positive regulation of NF-kappaB import into nucleus IEA GO:0042535 positive regulation of tumor necrosis factor biosynthetic process IEA GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB cascade IEA GO:0045084 positive regulation of interleukin-12 biosynthetic process IEA GO:0045087 innate immune response IEA GO:0045348 positive regulation of MHC class II biosynthetic process IEA GO:0045359 positive regulation of interferon-beta biosynthetic process IEA GO:0045416 positive regulation of interleukin-8 biosynthetic process IEA GO:0045429 positive regulation of nitric oxide biosynthetic process IEA GO:0045944 positive regulation of transcription from RNA polymerase II promoter IEA GO:0046330 positive regulation of JNK cascade IEA GO:0050727 regulation of inflammatory response IEA GO:0050829 defense response to Gram-negative bacterium IEA GO:0051092 positive regulation of NF-kappaB transcription factor activity IEA GO:0051770 positive regulation of nitric-oxide synthase biosynthetic process IEA GO:0060729 intestinal epithelial structure maintenance IEA GO:0060907 positive regulation of macrophage cytokine production IEA GO:0070373 negative regulation of ERK1 and ERK2 cascade IEA GO:0070374 positive regulation of ERK1 and ERK2 cascade IEA GO:0070430 positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway IEA GO:0070434 positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway IEA GO:0071223 cellular response to lipoteichoic acid IEA GO:0071260 cellular response to mechanical stimulus IEA cellular_component GO:0005622 intracellular IEA GO:0005737 cytoplasm IEA GO:0005886 plasma membrane IEA GO:0005887 integral to plasma membrane IEA GO:0009897 external side of plasma membrane IEA GO:0016020 membrane IEA GO:0046696 lipopolysaccharide receptor complex IEA GO:0046696 lipopolysaccharide receptor complex ISS GO:0048471 perinuclear region of cytoplasm IEA molecular_function GO:0001530 lipopolysaccharide binding IEA GO:0001875 lipopolysaccharide receptor activity ISS GO:0004872 receptor activity IEA GO:0004888 transmembrane signaling receptor activity IEA

Protein-protein interaction details for TLR4 (Bos taurus) (Information is obtained from BioGRID)

Not available