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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for Smad2 (Rattus norvegicus)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0001657ureteric bud developmentIEA
GO:0001701in utero embryonic developmentIEA
GO:0001701in utero embryonic developmentISO
GO:0001707mesoderm formationISO
GO:0001707mesoderm formationISS
GO:0006351transcription, DNA-dependentISO
GO:0006468protein phosphorylationISO
GO:0007179transforming growth factor beta receptor signaling pathwayISO
GO:0007179transforming growth factor beta receptor signaling pathwayISS
GO:0007182common-partner SMAD protein phosphorylationIEA
GO:0007182common-partner SMAD protein phosphorylationISO
GO:0007183SMAD protein complex assemblyIEA
GO:0007183SMAD protein complex assemblyISO
GO:0007352zygotic specification of dorsal/ventral axisIEA
GO:0007352zygotic specification of dorsal/ventral axisISO
GO:0007369gastrulationIEA
GO:0007369gastrulationISO
GO:0007389pattern specification processISO
GO:0007492endoderm developmentIEA
GO:0007492endoderm developmentISO
GO:0007507heart developmentISO
GO:0008285negative regulation of cell proliferationIMP
GO:0009749response to glucose stimulusIEA
GO:0009749response to glucose stimulusISO
GO:0009791post-embryonic developmentIEA
GO:0009791post-embryonic developmentISO
GO:0009880embryonic pattern specificationIEA
GO:0009880embryonic pattern specificationISO
GO:0009952anterior/posterior pattern specificationISO
GO:0009952anterior/posterior pattern specificationISS
GO:0010718positive regulation of epithelial to mesenchymal transitionIEA
GO:0010718positive regulation of epithelial to mesenchymal transitionISO
GO:0017015regulation of transforming growth factor beta receptor signaling pathwayIEA
GO:0017015regulation of transforming growth factor beta receptor signaling pathwayISO
GO:0030073insulin secretionIEA
GO:0030073insulin secretionISO
GO:0030324lung developmentIEA
GO:0030324lung developmentISO
GO:0031016pancreas developmentIEA
GO:0031016pancreas developmentISO
GO:0035265organ growthIEA
GO:0035265organ growthISO
GO:0035556intracellular signal transductionISO
GO:0035556intracellular signal transductionISS
GO:0045165cell fate commitmentISO
GO:0045165cell fate commitmentISS
GO:0045892negative regulation of transcription, DNA-dependentIEA
GO:0045892negative regulation of transcription, DNA-dependentISO
GO:0045893positive regulation of transcription, DNA-dependentISO
GO:0045893positive regulation of transcription, DNA-dependentISS
GO:0045944positive regulation of transcription from RNA polymerase II promoterISO
GO:0045944positive regulation of transcription from RNA polymerase II promoterISS
GO:0048340paraxial mesoderm morphogenesisISO
GO:0048340paraxial mesoderm morphogenesisISS
GO:0048589developmental growthIEA
GO:0048589developmental growthISO
GO:0048617embryonic foregut morphogenesisIEA
GO:0048617embryonic foregut morphogenesisISO
GO:0048701embryonic cranial skeleton morphogenesisIEA
GO:0048701embryonic cranial skeleton morphogenesisISO
GO:0051098regulation of bindingISO
GO:0051098regulation of bindingISS
GO:0060021palate developmentIEA
GO:0060021palate developmentISO
GO:0060039pericardium developmentIEA
GO:0060039pericardium developmentISO
GO:0070723response to cholesterolIEA
GO:0070723response to cholesterolISO
cellular_component
GO:0005634nucleusIDA
GO:0005634nucleusISO
GO:0005634nucleusISS
GO:0005654nucleoplasmIEA
GO:0005667transcription factor complexISO
GO:0005667transcription factor complexISS
GO:0005737cytoplasmIDA
GO:0005737cytoplasmISO
GO:0005829cytosolIEA
GO:0032444activin responsive factor complexIEA
GO:0032444activin responsive factor complexISO
GO:0043234protein complexIDA
GO:0071141SMAD protein complexISO
molecular_function
GO:0003677DNA bindingIEA
GO:0003677DNA bindingISO
GO:0003682chromatin bindingIEA
GO:0003682chromatin bindingISO
GO:0003690double-stranded DNA bindingISO
GO:0003690double-stranded DNA bindingISS
GO:0003700sequence-specific DNA binding transcription factor activityIEA
GO:0003700sequence-specific DNA binding transcription factor activityISO
GO:0005160transforming growth factor beta receptor bindingISO
GO:0005515protein bindingIPI
GO:0008134transcription factor bindingIPI
GO:0008134transcription factor bindingISO
GO:0008134transcription factor bindingISS
GO:0019902phosphatase bindingISO
GO:0030618transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activityIEA
GO:0030618transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activityISO
GO:0031625ubiquitin protein ligase bindingIEA
GO:0031625ubiquitin protein ligase bindingISO
GO:0033613activating transcription factor bindingISO
GO:0034713type I transforming growth factor beta receptor bindingIEA
GO:0034713type I transforming growth factor beta receptor bindingISO
GO:0046332SMAD bindingISO
GO:0070410co-SMAD bindingIEA
GO:0070410co-SMAD bindingISO
GO:0070411I-SMAD bindingIEA
GO:0070411I-SMAD bindingISO
GO:0070412R-SMAD bindingIEA
GO:0070412R-SMAD bindingISO

Protein-protein interaction details for Smad2 (Rattus norvegicus)
(Information is obtained from BioGRID)
Interacting proteinExperimentTypePubMed ID
Klf4Affinity Capture-Westernphysical20375011
Klf4Co-localizationphysical20375011