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Gene
Protein
Transcript
Promoter
Expression
GO/PPI
PubMed
Cross reference
Gene Ontology information for Shh (
Rattus norvegicus
)
(Information is obtained from AmiGO)
ID
Term
Evidence
biological_process
GO:0000122
negative regulation of transcription from RNA polymerase II promoter
ISO
GO:0001525
angiogenesis
ISO
GO:0001569
patterning of blood vessels
ISO
GO:0001569
patterning of blood vessels
ISS
GO:0001570
vasculogenesis
ISO
GO:0001570
vasculogenesis
ISS
GO:0001656
metanephros development
ISO
GO:0001656
metanephros development
ISS
GO:0001658
branching involved in ureteric bud morphogenesis
ISO
GO:0001658
branching involved in ureteric bud morphogenesis
ISS
GO:0001666
response to hypoxia
IEP
GO:0001708
cell fate specification
ISO
GO:0001708
cell fate specification
ISS
GO:0001755
neural crest cell migration
ISO
GO:0001755
neural crest cell migration
ISS
GO:0001822
kidney development
ISO
GO:0001841
neural tube formation
IMP
GO:0001942
hair follicle development
ISO
GO:0001944
vasculature development
IEA
GO:0001944
vasculature development
ISO
GO:0001947
heart looping
IEA
GO:0001947
heart looping
ISO
GO:0002052
positive regulation of neuroblast proliferation
IDA
GO:0002052
positive regulation of neuroblast proliferation
ISO
GO:0002053
positive regulation of mesenchymal cell proliferation
ISO
GO:0002076
osteoblast development
IEA
GO:0002076
osteoblast development
ISO
GO:0002320
lymphoid progenitor cell differentiation
ISO
GO:0002320
lymphoid progenitor cell differentiation
ISS
GO:0006355
regulation of transcription, DNA-dependent
ISO
GO:0006897
endocytosis
IEA
GO:0006897
endocytosis
ISO
GO:0006915
apoptosis
ISO
GO:0007165
signal transduction
ISO
GO:0007224
smoothened signaling pathway
ISO
GO:0007224
smoothened signaling pathway
ISS
GO:0007224
smoothened signaling pathway
TAS
GO:0007228
positive regulation of hh target transcription factor activity
IEA
GO:0007228
positive regulation of hh target transcription factor activity
ISO
GO:0007267
cell-cell signaling
ISO
GO:0007267
cell-cell signaling
ISS
GO:0007368
determination of left/right symmetry
IEA
GO:0007368
determination of left/right symmetry
ISO
GO:0007389
pattern specification process
ISO
GO:0007389
pattern specification process
ISS
GO:0007398
ectoderm development
IEA
GO:0007398
ectoderm development
ISO
GO:0007405
neuroblast proliferation
IEP
GO:0007405
neuroblast proliferation
ISO
GO:0007405
neuroblast proliferation
ISS
GO:0007411
axon guidance
ISO
GO:0007411
axon guidance
ISS
GO:0007417
central nervous system development
ISO
GO:0007417
central nervous system development
ISS
GO:0007442
hindgut morphogenesis
IEA
GO:0007442
hindgut morphogenesis
ISO
GO:0007502
digestive tract mesoderm development
IDA
GO:0007507
heart development
ISO
GO:0007507
heart development
ISS
GO:0007596
blood coagulation
IEA
GO:0007596
blood coagulation
ISO
GO:0008209
androgen metabolic process
ISO
GO:0008209
androgen metabolic process
ISS
GO:0008219
cell death
IEA
GO:0008219
cell death
ISO
GO:0008283
cell proliferation
ISO
GO:0008284
positive regulation of cell proliferation
IDA
GO:0008284
positive regulation of cell proliferation
ISO
GO:0008284
positive regulation of cell proliferation
ISS
GO:0009790
embryo development
ISO
GO:0009790
embryo development
ISS
GO:0009952
anterior/posterior pattern specification
IEA
GO:0009952
anterior/posterior pattern specification
ISO
GO:0009953
dorsal/ventral pattern formation
ISO
GO:0009953
dorsal/ventral pattern formation
ISS
GO:0010243
response to organic nitrogen
IEP
GO:0010463
mesenchymal cell proliferation
ISO
GO:0010468
regulation of gene expression
ISO
GO:0010628
positive regulation of gene expression
ISO
GO:0010629
negative regulation of gene expression
ISO
GO:0014003
oligodendrocyte development
IEA
GO:0014003
oligodendrocyte development
ISO
GO:0014706
striated muscle tissue development
IEA
GO:0014706
striated muscle tissue development
ISO
GO:0014858
positive regulation of skeletal muscle cell proliferation
IEA
GO:0014858
positive regulation of skeletal muscle cell proliferation
ISO
GO:0014902
myotube differentiation
IEA
GO:0014902
myotube differentiation
ISO
GO:0016539
intein-mediated protein splicing
IEA
GO:0021513
spinal cord dorsal/ventral patterning
IDA
GO:0021513
spinal cord dorsal/ventral patterning
ISO
GO:0021521
ventral spinal cord interneuron specification
IDA
GO:0021904
dorsal/ventral neural tube patterning
IEA
GO:0021904
dorsal/ventral neural tube patterning
ISO
GO:0021938
smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation
IEA
GO:0021938
smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation
ISO
GO:0021940
positive regulation of cerebellar granule cell precursor proliferation
IEA
GO:0021940
positive regulation of cerebellar granule cell precursor proliferation
ISO
GO:0021978
telencephalon regionalization
IMP
GO:0021978
telencephalon regionalization
ISO
GO:0030010
establishment of cell polarity
IEA
GO:0030010
establishment of cell polarity
ISO
GO:0030162
regulation of proteolysis
ISO
GO:0030162
regulation of proteolysis
ISS
GO:0030177
positive regulation of Wnt receptor signaling pathway
IEA
GO:0030177
positive regulation of Wnt receptor signaling pathway
ISO
GO:0030178
negative regulation of Wnt receptor signaling pathway
ISO
GO:0030323
respiratory tube development
ISO
GO:0030324
lung development
ISO
GO:0030324
lung development
ISS
GO:0030326
embryonic limb morphogenesis
ISO
GO:0030326
embryonic limb morphogenesis
ISS
GO:0030336
negative regulation of cell migration
ISO
GO:0030336
negative regulation of cell migration
ISS
GO:0030539
male genitalia development
ISO
GO:0030539
male genitalia development
ISS
GO:0030850
prostate gland development
IEP
GO:0030850
prostate gland development
ISO
GO:0030850
prostate gland development
ISS
GO:0030856
regulation of epithelial cell differentiation
IEP
GO:0030878
thyroid gland development
IEA
GO:0030878
thyroid gland development
ISO
GO:0030900
forebrain development
ISO
GO:0030900
forebrain development
ISS
GO:0030901
midbrain development
ISO
GO:0030901
midbrain development
ISS
GO:0030902
hindbrain development
ISO
GO:0030902
hindbrain development
ISS
GO:0031016
pancreas development
IEA
GO:0031016
pancreas development
ISO
GO:0031069
hair follicle morphogenesis
IEA
GO:0031069
hair follicle morphogenesis
ISO
GO:0032355
response to estradiol stimulus
IEP
GO:0032435
negative regulation of proteasomal ubiquitin-dependent protein catabolic process
IEA
GO:0032435
negative regulation of proteasomal ubiquitin-dependent protein catabolic process
ISO
GO:0032526
response to retinoic acid
IEP
GO:0033077
T cell differentiation in thymus
ISO
GO:0033077
T cell differentiation in thymus
ISS
GO:0033089
positive regulation of T cell differentiation in thymus
ISO
GO:0033089
positive regulation of T cell differentiation in thymus
ISS
GO:0033092
positive regulation of immature T cell proliferation in thymus
ISO
GO:0033092
positive regulation of immature T cell proliferation in thymus
ISS
GO:0034244
negative regulation of transcription elongation from RNA polymerase II promoter
ISO
GO:0034504
protein localization to nucleus
ISO
GO:0035115
embryonic forelimb morphogenesis
IEA
GO:0035115
embryonic forelimb morphogenesis
ISO
GO:0035116
embryonic hindlimb morphogenesis
IEA
GO:0035116
embryonic hindlimb morphogenesis
ISO
GO:0042127
regulation of cell proliferation
IDA
GO:0042127
regulation of cell proliferation
ISO
GO:0042127
regulation of cell proliferation
ISS
GO:0042130
negative regulation of T cell proliferation
IEA
GO:0042130
negative regulation of T cell proliferation
ISO
GO:0042177
negative regulation of protein catabolic process
ISO
GO:0042307
positive regulation of protein import into nucleus
IEA
GO:0042307
positive regulation of protein import into nucleus
ISO
GO:0042475
odontogenesis of dentine-containing tooth
IEA
GO:0042475
odontogenesis of dentine-containing tooth
ISO
GO:0042476
odontogenesis
ISO
GO:0042733
embryonic digit morphogenesis
ISO
GO:0042733
embryonic digit morphogenesis
ISS
GO:0042981
regulation of apoptosis
ISO
GO:0043010
camera-type eye development
IEA
GO:0043010
camera-type eye development
ISO
GO:0043066
negative regulation of apoptosis
IMP
GO:0043369
CD4-positive or CD8-positive, alpha-beta T cell lineage commitment
ISO
GO:0043369
CD4-positive or CD8-positive, alpha-beta T cell lineage commitment
ISS
GO:0043587
tongue morphogenesis
IMP
GO:0043588
skin development
IEA
GO:0043588
skin development
ISO
GO:0045059
positive thymic T cell selection
ISO
GO:0045059
positive thymic T cell selection
ISS
GO:0045060
negative thymic T cell selection
ISO
GO:0045060
negative thymic T cell selection
ISS
GO:0045109
intermediate filament organization
IEA
GO:0045109
intermediate filament organization
ISO
GO:0045165
cell fate commitment
ISO
GO:0045445
myoblast differentiation
IEA
GO:0045445
myoblast differentiation
ISO
GO:0045471
response to ethanol
IDA
GO:0045596
negative regulation of cell differentiation
ISO
GO:0045596
negative regulation of cell differentiation
ISS
GO:0045597
positive regulation of cell differentiation
ISO
GO:0045666
positive regulation of neuron differentiation
IMP
GO:0045893
positive regulation of transcription, DNA-dependent
ISO
GO:0045893
positive regulation of transcription, DNA-dependent
ISS
GO:0045944
positive regulation of transcription from RNA polymerase II promoter
IEA
GO:0045944
positive regulation of transcription from RNA polymerase II promoter
ISO
GO:0046534
positive regulation of photoreceptor cell differentiation
IDA
GO:0046638
positive regulation of alpha-beta T cell differentiation
ISO
GO:0046638
positive regulation of alpha-beta T cell differentiation
ISS
GO:0046639
negative regulation of alpha-beta T cell differentiation
IEA
GO:0046639
negative regulation of alpha-beta T cell differentiation
ISO
GO:0048468
cell development
ISO
GO:0048468
cell development
ISS
GO:0048538
thymus development
ISO
GO:0048538
thymus development
ISS
GO:0048546
digestive tract morphogenesis
ISO
GO:0048557
embryonic digestive tract morphogenesis
IEA
GO:0048557
embryonic digestive tract morphogenesis
ISO
GO:0048568
embryonic organ development
IEA
GO:0048568
embryonic organ development
ISO
GO:0048589
developmental growth
IEA
GO:0048589
developmental growth
ISO
GO:0048598
embryonic morphogenesis
ISO
GO:0048617
embryonic foregut morphogenesis
IEA
GO:0048617
embryonic foregut morphogenesis
ISO
GO:0048643
positive regulation of skeletal muscle tissue development
IEA
GO:0048643
positive regulation of skeletal muscle tissue development
ISO
GO:0048645
organ formation
IEA
GO:0048645
organ formation
ISO
GO:0048646
anatomical structure formation involved in morphogenesis
ISO
GO:0048663
neuron fate commitment
ISO
GO:0048663
neuron fate commitment
ISS
GO:0048678
response to axon injury
IMP
GO:0048706
embryonic skeletal system development
IEA
GO:0048706
embryonic skeletal system development
ISO
GO:0048709
oligodendrocyte differentiation
ISO
GO:0048714
positive regulation of oligodendrocyte differentiation
IEA
GO:0048714
positive regulation of oligodendrocyte differentiation
ISO
GO:0048754
branching morphogenesis of a tube
ISO
GO:0048754
branching morphogenesis of a tube
ISS
GO:0048808
male genitalia morphogenesis
IMP
GO:0048839
inner ear development
IEA
GO:0048839
inner ear development
ISO
GO:0048856
anatomical structure development
ISO
GO:0048859
formation of anatomical boundary
IEA
GO:0048859
formation of anatomical boundary
ISO
GO:0048864
stem cell development
ISO
GO:0048864
stem cell development
ISS
GO:0051146
striated muscle cell differentiation
ISO
GO:0051155
positive regulation of striated muscle cell differentiation
IEA
GO:0051155
positive regulation of striated muscle cell differentiation
ISO
GO:0060020
Bergmann glial cell differentiation
IEA
GO:0060020
Bergmann glial cell differentiation
ISO
GO:0060021
palate development
IEA
GO:0060021
palate development
ISO
GO:0060070
canonical Wnt receptor signaling pathway
ISO
GO:0060173
limb development
IEA
GO:0060173
limb development
ISO
GO:0060174
limb bud formation
IEA
GO:0060174
limb bud formation
ISO
GO:0060406
positive regulation of penile erection
IMP
GO:0060425
lung morphogenesis
ISO
GO:0060428
lung epithelium development
IEA
GO:0060428
lung epithelium development
ISO
GO:0060438
trachea development
ISO
GO:0060439
trachea morphogenesis
IEA
GO:0060439
trachea morphogenesis
ISO
GO:0060441
epithelial tube branching involved in lung morphogenesis
IEP
GO:0060441
epithelial tube branching involved in lung morphogenesis
ISO
GO:0060442
branching involved in prostate gland morphogenesis
ISO
GO:0060445
branching involved in salivary gland morphogenesis
IEA
GO:0060445
branching involved in salivary gland morphogenesis
ISO
GO:0060447
bud outgrowth involved in lung branching
IEA
GO:0060447
bud outgrowth involved in lung branching
ISO
GO:0060458
right lung development
IEA
GO:0060458
right lung development
ISO
GO:0060459
left lung development
IEA
GO:0060459
left lung development
ISO
GO:0060463
lung lobe morphogenesis
IEA
GO:0060463
lung lobe morphogenesis
ISO
GO:0060484
lung-associated mesenchyme development
IEA
GO:0060484
lung-associated mesenchyme development
ISO
GO:0060513
prostatic bud formation
ISO
GO:0060516
primary prostatic bud elongation
IEA
GO:0060516
primary prostatic bud elongation
ISO
GO:0060523
prostate epithelial cord elongation
IEA
GO:0060523
prostate epithelial cord elongation
ISO
GO:0060662
salivary gland cavitation
IEA
GO:0060662
salivary gland cavitation
ISO
GO:0060664
epithelial cell proliferation involved in salivary gland morphogenesis
IEA
GO:0060664
epithelial cell proliferation involved in salivary gland morphogenesis
ISO
GO:0060684
epithelial-mesenchymal cell signaling
ISO
GO:0060685
regulation of prostatic bud formation
IEA
GO:0060685
regulation of prostatic bud formation
ISO
GO:0060738
epithelial-mesenchymal signaling involved in prostate gland development
ISO
GO:0060768
regulation of epithelial cell proliferation involved in prostate gland development
ISO
GO:0060769
positive regulation of epithelial cell proliferation involved in prostate gland development
IEA
GO:0060769
positive regulation of epithelial cell proliferation involved in prostate gland development
ISO
GO:0060782
regulation of mesenchymal cell proliferation involved in prostate gland development
IEA
GO:0060782
regulation of mesenchymal cell proliferation involved in prostate gland development
ISO
GO:0060783
mesenchymal smoothened signaling pathway involved in prostate gland development
IEA
GO:0060783
mesenchymal smoothened signaling pathway involved in prostate gland development
ISO
GO:0060840
artery development
IEA
GO:0060840
artery development
ISO
GO:0060916
mesenchymal cell proliferation involved in lung development
IEA
GO:0060916
mesenchymal cell proliferation involved in lung development
ISO
GO:0061056
sclerotome development
IEA
GO:0061056
sclerotome development
ISO
GO:0070447
positive regulation of oligodendrocyte progenitor proliferation
IDA
GO:0071285
cellular response to lithium ion
IEA
GO:0071285
cellular response to lithium ion
ISO
GO:0072001
renal system development
ISO
GO:0072136
metanephric mesenchymal cell proliferation involved in metanephros development
ISO
GO:0072136
metanephric mesenchymal cell proliferation involved in metanephros development
ISS
GO:0080125
multicellular structure septum development
IEA
GO:0080125
multicellular structure septum development
ISO
GO:0090090
negative regulation of canonical Wnt receptor signaling pathway
IEA
GO:0090090
negative regulation of canonical Wnt receptor signaling pathway
ISO
GO:2000062
negative regulation of ureter smooth muscle cell differentiation
ISO
GO:2000062
negative regulation of ureter smooth muscle cell differentiation
ISS
GO:2000063
positive regulation of ureter smooth muscle cell differentiation
ISO
GO:2000063
positive regulation of ureter smooth muscle cell differentiation
ISS
GO:2000357
negative regulation of kidney smooth muscle cell differentiation
ISO
GO:2000357
negative regulation of kidney smooth muscle cell differentiation
ISS
GO:2000358
positive regulation of kidney smooth muscle cell differentiation
ISO
GO:2000358
positive regulation of kidney smooth muscle cell differentiation
ISS
GO:2000729
positive regulation of mesenchymal cell proliferation involved in ureter development
ISO
GO:2000729
positive regulation of mesenchymal cell proliferation involved in ureter development
ISS
cellular_component
GO:0005576
extracellular region
IEA
GO:0005615
extracellular space
IDA
GO:0005615
extracellular space
ISO
GO:0005615
extracellular space
ISS
GO:0005624
membrane fraction
IEA
GO:0005624
membrane fraction
ISO
GO:0005634
nucleus
IEA
GO:0005634
nucleus
ISO
GO:0005783
endoplasmic reticulum
IDA
GO:0005794
Golgi apparatus
IDA
GO:0005886
plasma membrane
IEA
GO:0009986
cell surface
ISO
GO:0009986
cell surface
ISS
GO:0030133
transport vesicle
IDA
GO:0031012
extracellular matrix
IEA
GO:0031012
extracellular matrix
ISO
GO:0045121
membrane raft
IDA
GO:0045121
membrane raft
ISO
GO:0045121
membrane raft
ISS
molecular_function
GO:0001948
glycoprotein binding
IEA
GO:0001948
glycoprotein binding
ISO
GO:0004871
signal transducer activity
ISO
GO:0004871
signal transducer activity
ISS
GO:0005102
receptor binding
TAS
GO:0005113
patched binding
IEA
GO:0005113
patched binding
ISO
GO:0005509
calcium ion binding
ISO
GO:0005509
calcium ion binding
ISS
GO:0005515
protein binding
IPI
GO:0005539
glycosaminoglycan binding
IEA
GO:0005539
glycosaminoglycan binding
ISO
GO:0008233
peptidase activity
IEA
GO:0008270
zinc ion binding
ISO
GO:0008270
zinc ion binding
ISS
GO:0016787
hydrolase activity
ISO
GO:0043237
laminin-1 binding
ISO
GO:0043237
laminin-1 binding
ISS
Protein-protein interaction details for Shh (
Rattus norvegicus
)
(Information is obtained from BioGRID)
Not available