Home

Search

Browse

Statistics

User guide

FAQs

Links

Questions

Contribute

Download

Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for HMGB1 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000122 negative regulation of transcription from RNA polymerase II promoter IMP GO:0001654 eye development IEA GO:0001773 myeloid dendritic cell activation ISS GO:0002407 dendritic cell chemotaxis ISS GO:0002437 inflammatory response to antigenic stimulus IEP GO:0006265 DNA topological change ISS GO:0006288 base-excision repair, DNA ligation IDA GO:0006309 DNA fragmentation involved in apoptotic nuclear change TAS GO:0006310 DNA recombination ISS GO:0006351 transcription, DNA-dependent IDA GO:0006357 regulation of transcription from RNA polymerase II promoter IDA GO:0006915 apoptosis TAS GO:0006921 cellular component disassembly involved in apoptosis TAS GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly IDA GO:0030324 lung development IEA GO:0031175 neuron projection development ISS GO:0033151 V(D)J recombination IDA GO:0043065 positive regulation of apoptosis IDA GO:0043280 positive regulation of caspase activity IDA GO:0043388 positive regulation of DNA binding IDA GO:0045087 innate immune response TAS GO:0045639 positive regulation of myeloid cell differentiation IEA GO:0045819 positive regulation of glycogen catabolic process IEA GO:0045944 positive regulation of transcription from RNA polymerase II promoter IDA GO:0045944 positive regulation of transcription from RNA polymerase II promoter IEA GO:0050918 positive chemotaxis ISS GO:0051103 DNA ligation involved in DNA repair ISS GO:0051384 response to glucocorticoid stimulus IEA cellular_component GO:0000793 condensed chromosome IDA GO:0005576 extracellular region TAS GO:0005615 extracellular space IDA GO:0005615 extracellular space IEA GO:0005625 soluble fraction IEA GO:0005634 nucleus IDA GO:0005634 nucleus IEA GO:0005654 nucleoplasm TAS GO:0005730 nucleolus IDA GO:0005737 cytoplasm IEA GO:0009986 cell surface IDA GO:0017053 transcriptional repressor complex IDA GO:0043005 neuron projection IEA molecular_function GO:0003677 DNA binding IEA GO:0003684 damaged DNA binding ISS GO:0003690 double-stranded DNA binding ISS GO:0003697 single-stranded DNA binding ISS GO:0003700 sequence-specific DNA binding transcription factor activity IDA GO:0005125 cytokine activity IEA GO:0005125 cytokine activity ISS GO:0005515 protein binding IPI GO:0008134 transcription factor binding IPI GO:0008301 DNA bending activity IMP GO:0008301 DNA bending activity ISS GO:0010858 calcium-dependent protein kinase regulator activity IEA GO:0030295 protein kinase activator activity IEA GO:0042056 chemoattractant activity ISS GO:0050786 RAGE receptor binding ISS GO:0070491 repressing transcription factor binding IPI

Protein-protein interaction details for HMGB1 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID RELA Affinity Capture-Western physical 12665595 NFKB1 Reconstituted Complex physical 12604365 C14orf1 Two-hybrid physical 16169070 CRMP1 Two-hybrid physical 16169070 C1orf103 Two-hybrid physical 16169070 UNC119 Two-hybrid physical 16169070 CSNK1A1 Co-purification physical 12062430 TP53 Affinity Capture-Western physical 11106654 TP53 Affinity Capture-Western physical 11106654 TP53 Reconstituted Complex physical 11106654 TP53 Reconstituted Complex physical 11106654 HOXB1 Reconstituted Complex physical 8890171 HOXB3 Reconstituted Complex physical 8890171 HOXC6 Reconstituted Complex physical 8890171 HOXD3 Reconstituted Complex physical 8890171 HOXD8 Reconstituted Complex physical 8890171 HOXD9 Reconstituted Complex physical 8890171 HOXD10 Reconstituted Complex physical 8890171 HOXD11 Reconstituted Complex physical 8890171 PLG Reconstituted Complex physical 1909331 POU5F1 Affinity Capture-Western physical 11099378 NCAN Reconstituted Complex physical 9507007 PTPRZ1 Reconstituted Complex physical 9507007 TP53 Reconstituted Complex physical 11748221 RB1 Reconstituted Complex physical 11748221 HNRNPK Reconstituted Complex physical 11748221 MECP2 Reconstituted Complex physical 11748221 TLE1 Reconstituted Complex physical 11748221 AES Reconstituted Complex physical 11748221 TBP Reconstituted Complex physical 9880542 GTF2A1 Reconstituted Complex physical 9880542 PLAT Co-purification physical 8366113 RAG1 Reconstituted Complex physical 10490593 RAG1 Reconstituted Complex physical 10490593 PGR Reconstituted Complex physical 9671457 NR3C1 Reconstituted Complex physical 9671457 AR Reconstituted Complex physical 9671457 TP73 Reconstituted Complex physical 11748232 UBC Affinity Capture-MS physical 18655026 CDK1 Biochemical Activity physical 2013279 CDK1 Reconstituted Complex physical 2013279 TBP Reconstituted Complex physical 8006019 CREBBP Biochemical Activity physical 15005629 H3F3A Affinity Capture-MS physical 17403666 POU5F1 Affinity Capture-RNA physical 21151833 HMGB2 Affinity Capture-Western physical 12517784 PDIA3 Affinity Capture-Western physical 12517784 HSPA8 Affinity Capture-Western physical 12517784 DNM2 Two-hybrid physical 21900206 FCP1 Affinity Capture-MS physical 12591939