Database of mammalian genes
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Gene
Protein
Transcript
Promoter
Expression
GO/PPI
PubMed
Cross reference
Gene Ontology information for Mdm2 (
Rattus norvegicus
)
(Information is obtained from AmiGO)
ID
Term
Evidence
biological_process
GO:0000122
negative regulation of transcription from RNA polymerase II promoter
ISO
GO:0006461
protein complex assembly
IEA
GO:0006461
protein complex assembly
ISO
GO:0007089
traversing start control point of mitotic cell cycle
IEA
GO:0007089
traversing start control point of mitotic cell cycle
ISO
GO:0009636
response to toxin
IEP
GO:0009743
response to carbohydrate stimulus
IEP
GO:0010039
response to iron ion
IEP
GO:0010628
positive regulation of gene expression
IMP
GO:0010629
negative regulation of gene expression
IMP
GO:0010955
negative regulation of protein processing
IMP
GO:0016567
protein ubiquitination
IMP
GO:0016567
protein ubiquitination
ISO
GO:0030163
protein catabolic process
ISO
GO:0031648
protein destabilization
IEA
GO:0031648
protein destabilization
ISO
GO:0032026
response to magnesium ion
IEP
GO:0032436
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
IEA
GO:0032436
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
ISO
GO:0034504
protein localization to nucleus
IEA
GO:0034504
protein localization to nucleus
ISO
GO:0042176
regulation of protein catabolic process
IEA
GO:0042176
regulation of protein catabolic process
ISO
GO:0042220
response to cocaine
IEP
GO:0042493
response to drug
IEP
GO:0042787
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
IEA
GO:0042787
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
ISO
GO:0043066
negative regulation of apoptosis
IEA
GO:0043066
negative regulation of apoptosis
IMP
GO:0043154
negative regulation of caspase activity
IMP
GO:0043278
response to morphine
IEP
GO:0043518
negative regulation of DNA damage response, signal transduction by p53 class mediator
IEA
GO:0043518
negative regulation of DNA damage response, signal transduction by p53 class mediator
ISO
GO:0045184
establishment of protein localization
IEA
GO:0045184
establishment of protein localization
ISO
GO:0045472
response to ether
IEP
GO:0045787
positive regulation of cell cycle
ISO
GO:0045892
negative regulation of transcription, DNA-dependent
IDA
GO:0045892
negative regulation of transcription, DNA-dependent
ISO
GO:0045931
positive regulation of mitotic cell cycle
IEA
GO:0045931
positive regulation of mitotic cell cycle
ISO
GO:0046677
response to antibiotic
IEA
GO:0046677
response to antibiotic
ISO
GO:0046827
positive regulation of protein export from nucleus
IMP
GO:0048545
response to steroid hormone stimulus
IEP
GO:0070301
cellular response to hydrogen peroxide
IEP
GO:0071157
negative regulation of cell cycle arrest
IEA
GO:0071157
negative regulation of cell cycle arrest
ISO
GO:0071229
cellular response to acid
IEP
GO:0071236
cellular response to antibiotic
IEP
GO:0071301
cellular response to vitamin B1
IEP
GO:0071310
cellular response to organic substance
IEP
GO:0071312
cellular response to alkaloid
IEP
GO:0071363
cellular response to growth factor stimulus
IEP
GO:0071375
cellular response to peptide hormone stimulus
IEP
GO:0071391
cellular response to estrogen stimulus
IEP
GO:0071407
cellular response to organic cyclic compound
IEP
GO:0071456
cellular response to hypoxia
IEA
GO:0071456
cellular response to hypoxia
ISO
GO:0071494
cellular response to UV-C
IEP
cellular_component
GO:0005622
intracellular
IEA
GO:0005625
soluble fraction
IDA
GO:0005626
insoluble fraction
ISO
GO:0005634
nucleus
IDA
GO:0005634
nucleus
ISO
GO:0005654
nucleoplasm
ISO
GO:0005730
nucleolus
ISO
GO:0005737
cytoplasm
ISO
GO:0005829
cytosol
IDA
GO:0005886
plasma membrane
IDA
GO:0016604
nuclear body
IEA
GO:0016604
nuclear body
ISO
GO:0030666
endocytic vesicle membrane
IEA
GO:0043234
protein complex
IEA
GO:0043234
protein complex
ISO
GO:0045202
synapse
IDA
molecular_function
GO:0002039
p53 binding
IPI
GO:0002039
p53 binding
ISO
GO:0004842
ubiquitin-protein ligase activity
IMP
GO:0004842
ubiquitin-protein ligase activity
ISO
GO:0005515
protein binding
IPI
GO:0008270
zinc ion binding
IEA
GO:0008270
zinc ion binding
ISO
GO:0019899
enzyme binding
IEA
GO:0019899
enzyme binding
ISO
GO:0042802
identical protein binding
IEA
GO:0042975
peroxisome proliferator activated receptor binding
IPI
GO:0046872
metal ion binding
IEA
Protein-protein interaction details for Mdm2 (
Rattus norvegicus
)
(Information is obtained from BioGRID)
Interacting protein
Experiment
Type
PubMed ID
Tp53
Affinity Capture-Western
physical
22046440
Hif1a
Affinity Capture-Western
physical
19950214