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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for Mdm2 (Rattus norvegicus)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0000122negative regulation of transcription from RNA polymerase II promoterISO
GO:0006461protein complex assemblyIEA
GO:0006461protein complex assemblyISO
GO:0007089traversing start control point of mitotic cell cycleIEA
GO:0007089traversing start control point of mitotic cell cycleISO
GO:0009636response to toxinIEP
GO:0009743response to carbohydrate stimulusIEP
GO:0010039response to iron ionIEP
GO:0010628positive regulation of gene expressionIMP
GO:0010629negative regulation of gene expressionIMP
GO:0010955negative regulation of protein processingIMP
GO:0016567protein ubiquitinationIMP
GO:0016567protein ubiquitinationISO
GO:0030163protein catabolic processISO
GO:0031648protein destabilizationIEA
GO:0031648protein destabilizationISO
GO:0032026response to magnesium ionIEP
GO:0032436positive regulation of proteasomal ubiquitin-dependent protein catabolic processIEA
GO:0032436positive regulation of proteasomal ubiquitin-dependent protein catabolic processISO
GO:0034504protein localization to nucleusIEA
GO:0034504protein localization to nucleusISO
GO:0042176regulation of protein catabolic processIEA
GO:0042176regulation of protein catabolic processISO
GO:0042220response to cocaineIEP
GO:0042493response to drugIEP
GO:0042787protein ubiquitination involved in ubiquitin-dependent protein catabolic processIEA
GO:0042787protein ubiquitination involved in ubiquitin-dependent protein catabolic processISO
GO:0043066negative regulation of apoptosisIEA
GO:0043066negative regulation of apoptosisIMP
GO:0043154negative regulation of caspase activityIMP
GO:0043278response to morphineIEP
GO:0043518negative regulation of DNA damage response, signal transduction by p53 class mediatorIEA
GO:0043518negative regulation of DNA damage response, signal transduction by p53 class mediatorISO
GO:0045184establishment of protein localizationIEA
GO:0045184establishment of protein localizationISO
GO:0045472response to etherIEP
GO:0045787positive regulation of cell cycleISO
GO:0045892negative regulation of transcription, DNA-dependentIDA
GO:0045892negative regulation of transcription, DNA-dependentISO
GO:0045931positive regulation of mitotic cell cycleIEA
GO:0045931positive regulation of mitotic cell cycleISO
GO:0046677response to antibioticIEA
GO:0046677response to antibioticISO
GO:0046827positive regulation of protein export from nucleusIMP
GO:0048545response to steroid hormone stimulusIEP
GO:0070301cellular response to hydrogen peroxideIEP
GO:0071157negative regulation of cell cycle arrestIEA
GO:0071157negative regulation of cell cycle arrestISO
GO:0071229cellular response to acidIEP
GO:0071236cellular response to antibioticIEP
GO:0071301cellular response to vitamin B1IEP
GO:0071310cellular response to organic substanceIEP
GO:0071312cellular response to alkaloidIEP
GO:0071363cellular response to growth factor stimulusIEP
GO:0071375cellular response to peptide hormone stimulusIEP
GO:0071391cellular response to estrogen stimulusIEP
GO:0071407cellular response to organic cyclic compoundIEP
GO:0071456cellular response to hypoxiaIEA
GO:0071456cellular response to hypoxiaISO
GO:0071494cellular response to UV-CIEP
cellular_component
GO:0005622intracellularIEA
GO:0005625soluble fractionIDA
GO:0005626insoluble fractionISO
GO:0005634nucleusIDA
GO:0005634nucleusISO
GO:0005654nucleoplasmISO
GO:0005730nucleolusISO
GO:0005737cytoplasmISO
GO:0005829cytosolIDA
GO:0005886plasma membraneIDA
GO:0016604nuclear bodyIEA
GO:0016604nuclear bodyISO
GO:0030666endocytic vesicle membraneIEA
GO:0043234protein complexIEA
GO:0043234protein complexISO
GO:0045202synapseIDA
molecular_function
GO:0002039p53 bindingIPI
GO:0002039p53 bindingISO
GO:0004842ubiquitin-protein ligase activityIMP
GO:0004842ubiquitin-protein ligase activityISO
GO:0005515protein bindingIPI
GO:0008270zinc ion bindingIEA
GO:0008270zinc ion bindingISO
GO:0019899enzyme bindingIEA
GO:0019899enzyme bindingISO
GO:0042802identical protein bindingIEA
GO:0042975peroxisome proliferator activated receptor bindingIPI
GO:0046872metal ion bindingIEA

Protein-protein interaction details for Mdm2 (Rattus norvegicus)
(Information is obtained from BioGRID)
Interacting proteinExperimentTypePubMed ID
Tp53Affinity Capture-Westernphysical22046440
Hif1aAffinity Capture-Westernphysical19950214