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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for HMGCL (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0001889 liver development IEA GO:0006637 acyl-CoA metabolic process IEA GO:0007005 mitochondrion organization IEA GO:0007584 response to nutrient IEA GO:0009790 embryo development IEA GO:0042594 response to starvation IEA GO:0043441 acetoacetic acid biosynthetic process TAS GO:0044255 cellular lipid metabolic process TAS GO:0046950 cellular ketone body metabolic process TAS GO:0046951 ketone body biosynthetic process IEA GO:0046951 ketone body biosynthetic process TAS GO:0070542 response to fatty acid IEA cellular_component GO:0005739 mitochondrion IEA GO:0005743 mitochondrial inner membrane IEA GO:0005759 mitochondrial matrix TAS molecular_function GO:0000062 fatty-acyl-CoA binding IEA GO:0003824 catalytic activity IEA GO:0004419 hydroxymethylglutaryl-CoA lyase activity IEA GO:0004419 hydroxymethylglutaryl-CoA lyase activity TAS GO:0016829 lyase activity IEA GO:0031406 carboxylic acid binding IEA GO:0046872 metal ion binding IDA

Protein-protein interaction details for HMGCL (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID MS4A7 Two-hybrid physical 16169070 HES1 Two-hybrid physical 21900206 DNAJA1 Two-hybrid physical 21900206 RNF126 Two-hybrid physical 21900206 ADAMTS10 Two-hybrid physical 21900206 ARL6IP1 Two-hybrid physical 21900206