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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for HMOX1 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0001525 angiogenesis TAS GO:0001666 response to hypoxia IEA GO:0001935 endothelial cell proliferation TAS GO:0002246 wound healing involved in inflammatory response IMP GO:0002686 negative regulation of leukocyte migration TAS GO:0006778 porphyrin-containing compound metabolic process TAS GO:0006788 heme oxidation IDA GO:0006788 heme oxidation IEA GO:0006879 cellular iron ion homeostasis TAS GO:0006916 anti-apoptosis IMP GO:0006979 response to oxidative stress IEA GO:0006979 response to oxidative stress IMP GO:0007165 signal transduction IMP GO:0007243 intracellular protein kinase cascade TAS GO:0007264 small GTPase mediated signal transduction IEA GO:0007588 excretion IC GO:0008217 regulation of blood pressure IEA GO:0008219 cell death IEA GO:0008219 cell death ISS GO:0008630 DNA damage response, signal transduction resulting in induction of apoptosis IEA GO:0014806 smooth muscle hyperplasia TAS GO:0031670 cellular response to nutrient IEA GO:0032764 negative regulation of mast cell cytokine production IEA GO:0034101 erythrocyte homeostasis IMP GO:0034383 low-density lipoprotein particle clearance TAS GO:0035094 response to nicotine IDA GO:0042167 heme catabolic process IDA GO:0042167 heme catabolic process IEA GO:0042167 heme catabolic process TAS GO:0042542 response to hydrogen peroxide IEA GO:0042542 response to hydrogen peroxide ISS GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB cascade IMP GO:0043305 negative regulation of mast cell degranulation IEA GO:0043392 negative regulation of DNA binding IEA GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity IEA GO:0043524 negative regulation of neuron apoptosis IEA GO:0043619 regulation of transcription from RNA polymerase II promoter in response to oxidative stress IEA GO:0043619 regulation of transcription from RNA polymerase II promoter in response to oxidative stress ISS GO:0043627 response to estrogen stimulus IEA GO:0045080 positive regulation of chemokine biosynthetic process TAS GO:0045765 regulation of angiogenesis TAS GO:0045766 positive regulation of angiogenesis IEA GO:0045768 positive regulation of anti-apoptosis IEA GO:0045909 positive regulation of vasodilation IC GO:0048661 positive regulation of smooth muscle cell proliferation IDA GO:0048662 negative regulation of smooth muscle cell proliferation IDA GO:0048662 negative regulation of smooth muscle cell proliferation IEA GO:0050896 response to stimulus IEA GO:0051090 regulation of sequence-specific DNA binding transcription factor activity ISS GO:0051260 protein homooligomerization IDA GO:0055072 iron ion homeostasis IDA GO:0055072 iron ion homeostasis IMP GO:0055085 transmembrane transport TAS GO:0071456 cellular response to hypoxia IEP cellular_component GO:0005615 extracellular space TAS GO:0005624 membrane fraction TAS GO:0005634 nucleus IEA GO:0005634 nucleus ISS GO:0005730 nucleolus IEA GO:0005783 endoplasmic reticulum IDA GO:0005783 endoplasmic reticulum IEA GO:0005783 endoplasmic reticulum ISS GO:0005789 endoplasmic reticulum membrane TAS GO:0005792 microsome IEA GO:0005792 microsome ISS GO:0005829 cytosol IEA GO:0005901 caveola IEA molecular_function GO:0004392 heme oxygenase (decyclizing) activity IDA GO:0004392 heme oxygenase (decyclizing) activity IEA GO:0004392 heme oxygenase (decyclizing) activity IMP GO:0004630 phospholipase D activity IEA GO:0004871 signal transducer activity IMP GO:0016491 oxidoreductase activity IEA GO:0019899 enzyme binding IEA GO:0019899 enzyme binding ISS GO:0020037 heme binding IDA GO:0020037 heme binding IEA GO:0042803 protein homodimerization activity IDA GO:0046872 metal ion binding IEA

Protein-protein interaction details for HMOX1 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID HMOX1 Co-crystal Structure physical 12500973 UBC Affinity Capture-Western physical 18544348 UFD1L Affinity Capture-Western physical 18544348 PSMD2 Affinity Capture-Western physical 18544348