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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for NR4A1 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0001938 positive regulation of endothelial cell proliferation IMP GO:0002042 cell migration involved in sprouting angiogenesis IDA GO:0006355 regulation of transcription, DNA-dependent IEA GO:0006917 induction of apoptosis IEA GO:0007165 signal transduction TAS GO:0008543 fibroblast growth factor receptor signaling pathway TAS GO:0010467 gene expression TAS GO:0030522 intracellular receptor mediated signaling pathway TAS GO:0034339 regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor TAS GO:0035767 endothelial cell chemotaxis IMP GO:0035924 cellular response to vascular endothelial growth factor stimulus IMP GO:0043154 negative regulation of caspase activity IEA GO:0044344 cellular response to fibroblast growth factor stimulus IMP GO:0048011 nerve growth factor receptor signaling pathway TAS GO:0048015 phosphatidylinositol-mediated signaling TAS cellular_component GO:0005634 nucleus IEA GO:0005634 nucleus ISS GO:0005654 nucleoplasm TAS GO:0005667 transcription factor complex IEA molecular_function GO:0001077 RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription IEA GO:0003677 DNA binding IEA GO:0003677 DNA binding ISS GO:0003700 sequence-specific DNA binding transcription factor activity IEA GO:0003707 steroid hormone receptor activity IEA GO:0004872 receptor activity IEA GO:0004879 ligand-dependent nuclear receptor activity IEA GO:0004879 ligand-dependent nuclear receptor activity TAS GO:0005515 protein binding IPI GO:0008270 zinc ion binding IEA GO:0042803 protein homodimerization activity IEA GO:0043565 sequence-specific DNA binding IEA GO:0046872 metal ion binding IEA GO:0046982 protein heterodimerization activity IEA

Protein-protein interaction details for NR4A1 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID GADD45GIP1 Affinity Capture-Western physical 15459248 BCL2 Reconstituted Complex physical 14980220 RXRA Reconstituted Complex physical 14980220 BCL2 Reconstituted Complex physical 14980220 BCL2 Two-hybrid physical 14980220 RXRA Two-hybrid physical 14980220 BCL2 Affinity Capture-Western physical 14980220 BCL2 Affinity Capture-Western physical 14980220 NCOA3 Reconstituted Complex physical 12082103 NCOA1 Reconstituted Complex physical 12082103 EP300 Reconstituted Complex physical 12082103 KAT2B Reconstituted Complex physical 12082103 RXRG Reconstituted Complex physical 12082103 FXYD3 Two-hybrid physical 16169070 RPS6KA6 Two-hybrid physical 16169070 AKT1 Affinity Capture-Western physical 11274386 AKT1 Biochemical Activity physical 11274386 PML Affinity Capture-Western physical 12032831 PML Affinity Capture-Western physical 12032831 PML Reconstituted Complex physical 12032831 PML Reconstituted Complex physical 12032831 NCOR2 Two-hybrid physical 11559707 NCOR2 Affinity Capture-Western physical 11559707 NCOR2 Reconstituted Complex physical 11559707 HIF1A Affinity Capture-Western physical 18305400 VHL Affinity Capture-Western physical 18305400 VHL Affinity Capture-Western physical 18305400 VHL Reconstituted Complex physical 18305400 HIF1A Affinity Capture-Western physical 18305400 TP53 Affinity Capture-Western physical 17139261 TP53 Reconstituted Complex physical 17139261 TP53 Reconstituted Complex physical 17139261 MAPK8 Biochemical Activity physical 17023523 CHD4 Affinity Capture-MS physical 19321449 TOP2A Affinity Capture-MS physical 19321449 PELP1 Affinity Capture-MS physical 19321449 SMARCC1 Affinity Capture-MS physical 19321449 MYBBP1A Affinity Capture-MS physical 19321449 MTA2 Affinity Capture-MS physical 19321449 TRIM28 Affinity Capture-MS physical 19321449 SMARCE1 Affinity Capture-MS physical 19321449 TMOD3 Affinity Capture-MS physical 19321449 EEF1A1 Affinity Capture-MS physical 19321449 HDAC6 Affinity Capture-MS physical 19321449 MTA2 Affinity Capture-Western physical 19321449 PELP1 Affinity Capture-Western physical 19321449 MYBBP1A Affinity Capture-Western physical 19321449 TRIM28 Affinity Capture-Western physical 19321449 TRIM28 Reconstituted Complex physical 19321449 SRC Affinity Capture-Western physical 16002533 NCOR2 Affinity Capture-Western physical 16002533 EP300 Biochemical Activity physical 20438716 POLA2 Two-hybrid physical 21900206 HES1 Two-hybrid physical 21900206 ROBO2 Two-hybrid physical 21900206 NR3C1 Two-hybrid physical 21900206 ZNF579 Two-hybrid physical 21900206 HSP90AB1 Two-hybrid physical 21900206 MED31 Two-hybrid physical 21900206 RPL7 Two-hybrid physical 21900206 RTN4 Two-hybrid physical 21900206 BBS10 Two-hybrid physical 21900206 NACAD Two-hybrid physical 21900206 ZNF331 Two-hybrid physical 21900206 PRDX4 Two-hybrid physical 21900206 GLOD4 Two-hybrid physical 21900206 HNRNPA2B1 Two-hybrid physical 21900206 TCF4 Two-hybrid physical 21900206 CHD3 Two-hybrid physical 21900206 SERPINA4 Two-hybrid physical 21900206 FAF1 Two-hybrid physical 21900206 PPBP Two-hybrid physical 21900206 UBC Affinity Capture-Western physical 21986938 CTNNB1 Affinity Capture-Western physical 21986938 CTNNB1 Affinity Capture-Western physical 21986938