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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for HSPA5 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0002576 platelet degranulation TAS GO:0006200 ATP catabolic process ISS GO:0006916 anti-apoptosis IMP GO:0006916 anti-apoptosis TAS GO:0006983 ER overload response IEA GO:0006987 activation of signaling protein activity involved in unfolded protein response IEA GO:0007596 blood coagulation TAS GO:0021589 cerebellum structural organization IEA GO:0021680 cerebellar Purkinje cell layer development IEA GO:0030168 platelet activation TAS GO:0030433 ER-associated protein catabolic process TAS GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway IEA GO:0030968 endoplasmic reticulum unfolded protein response TAS GO:0031398 positive regulation of protein ubiquitination IEA GO:0042149 cellular response to glucose starvation IDA GO:0043066 negative regulation of apoptosis IMP GO:0043154 negative regulation of caspase activity IDA GO:0051603 proteolysis involved in cellular protein catabolic process IEA GO:0060904 regulation of protein folding in endoplasmic reticulum TAS cellular_component GO:0005576 extracellular region IEA GO:0005634 nucleus IDA GO:0005783 endoplasmic reticulum IDA GO:0005783 endoplasmic reticulum TAS GO:0005788 endoplasmic reticulum lumen TAS GO:0005789 endoplasmic reticulum membrane TAS GO:0005793 endoplasmic reticulum-Golgi intermediate compartment IDA GO:0008180 signalosome IDA GO:0008303 caspase complex IDA GO:0009986 cell surface IDA GO:0030176 integral to endoplasmic reticulum membrane IDA GO:0030496 midbody IDA GO:0034663 endoplasmic reticulum chaperone complex IDA GO:0042470 melanosome IEA GO:0048471 perinuclear region of cytoplasm IDA molecular_function GO:0000166 nucleotide binding IEA GO:0005509 calcium ion binding TAS GO:0005515 protein binding IPI GO:0005524 ATP binding IEA GO:0005524 ATP binding NAS GO:0016887 ATPase activity ISS GO:0019904 protein domain specific binding IPI GO:0030674 protein binding, bridging NAS GO:0031625 ubiquitin protein ligase binding IPI GO:0043022 ribosome binding IEA GO:0043027 caspase inhibitor activity IDA GO:0051082 unfolded protein binding TAS GO:0051087 chaperone binding TAS GO:0051787 misfolded protein binding IDA

Protein-protein interaction details for HSPA5 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID DPH1 Two-hybrid physical 11013075 TCERG1 Affinity Capture-MS physical 15456888 ERN1 Reconstituted Complex physical 12637535 DDX24 Two-hybrid physical 16169070 PSME3 Two-hybrid physical 16169070 BCAR1 Two-hybrid physical 16169070 LCT Affinity Capture-Western physical 11751874 SIL1 Affinity Capture-Western physical 12356756 SIL1 Two-hybrid physical 12356756 CASP7 Affinity Capture-Western physical 11943137 CASP12 Affinity Capture-Western physical 11943137 TMEM132A Reconstituted Complex physical 12514190 VWF Affinity Capture-Western physical 10887119 EIF2AK3 Affinity Capture-Western physical 11907036 KRT8 Reconstituted Complex physical 9409741 A2M Reconstituted Complex physical 12194978 TSHR Affinity Capture-Western physical 12383251 HLA-C Affinity Capture-Western physical 7957306 LDLR Affinity Capture-MS physical 10906332 TG Reconstituted Complex physical 11294872 TG Reconstituted Complex physical 10049727 DNAJC10 Reconstituted Complex physical 12411443 UBQLN4 Two-hybrid physical 11162551 NHLRC1 Co-localization physical 17337485 EPM2A Co-localization physical 17337485 MEPCE Affinity Capture-MS physical 17643375 RUVBL2 Affinity Capture-MS physical 17643375 CDK9 Affinity Capture-MS physical 17643375 POLR3H Affinity Capture-MS physical 17643375 GRB2 Two-hybrid physical 20936779 SREBF2 Two-hybrid physical 20936779 APC Two-hybrid physical 20936779 H2AFX Affinity Capture-MS physical 16522924 AIRE Affinity Capture-MS physical 15150263 HDAC6 Affinity Capture-Western physical 20371724 HDAC6 Affinity Capture-Western physical 20371724 EIF2AK3 Affinity Capture-Western physical 20371724 TADA2A Affinity Capture-MS physical 20508642 DNMT1 Affinity Capture-MS physical 21745816 CBL Affinity Capture-MS physical 21203488 HAX1 Affinity Capture-MS physical 20171186 UBC Affinity Capture-MS physical 16196087 YY1 Co-localization physical 17721549 UCHL5 Affinity Capture-Western physical 21800051 UCHL5 Affinity Capture-Western physical 21800051 UCHL5 Co-localization physical 21800051 UCHL5 Reconstituted Complex physical 21800051 UCHL5 Affinity Capture-MS physical 21800051 SNW1 Affinity Capture-MS physical 12840015 EIF2C4 Affinity Capture-MS physical 19167051 DGCR8 Affinity Capture-MS physical 17765891 HDAC5 Affinity Capture-MS physical 21081666 SPG20 Affinity Capture-MS physical 19765186 SPG20 Affinity Capture-Western physical 19765186 SRC Affinity Capture-MS physical 16051665 UBC Reconstituted Complex physical 19850743 DYRK2 Affinity Capture-MS physical 19287380 YWHAB Affinity Capture-MS physical 15324660 SIRT1 Affinity Capture-MS physical 19343720 SIRT3 Affinity Capture-MS physical 19343720 INSIG2 Affinity Capture-MS physical 19815544 TP53 Affinity Capture-Western physical 17184779 SYVN1 Affinity Capture-Western physical 21903092 AMFR Affinity Capture-MS physical 21343306 PAWR Affinity Capture-MS physical 19632185 PAWR Affinity Capture-Western physical 19632185 PAWR Affinity Capture-Western physical 19632185 PSMA3 Affinity Capture-MS physical 22079093 RAF1 Reconstituted Complex physical 18064632 SUMO1 Affinity Capture-MS physical 19596686 RAF1 Affinity Capture-Western physical 18064632 RAF1 Affinity Capture-Western physical 18064632 UBC Affinity Capture-MS physical 22178446 UBC Affinity Capture-MS physical 18781797 UBC Affinity Capture-MS physical 21987572 RNF146 Affinity Capture-MS physical 21825151