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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for HSPB1 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0001525 angiogenesis IMP GO:0006446 regulation of translational initiation TAS GO:0006469 negative regulation of protein kinase activity IEA GO:0006469 negative regulation of protein kinase activity ISS GO:0006916 anti-apoptosis TAS GO:0006928 cellular component movement TAS GO:0006950 response to stress IEA GO:0006986 response to unfolded protein NAS GO:0008219 cell death IEA GO:0009615 response to virus IEP GO:0016070 RNA metabolic process TAS GO:0016071 mRNA metabolic process TAS GO:0032731 positive regulation of interleukin-1 beta production IEA GO:0032731 positive regulation of interleukin-1 beta production ISS GO:0035767 endothelial cell chemotaxis IMP GO:0035924 cellular response to vascular endothelial growth factor stimulus IMP GO:0042535 positive regulation of tumor necrosis factor biosynthetic process IEA GO:0042535 positive regulation of tumor necrosis factor biosynthetic process ISS GO:0043066 negative regulation of apoptosis IEA GO:0043066 negative regulation of apoptosis ISS GO:0043122 regulation of I-kappaB kinase/NF-kappaB cascade IEA GO:0043122 regulation of I-kappaB kinase/NF-kappaB cascade ISS GO:0043534 blood vessel endothelial cell migration IMP cellular_component GO:0000502 proteasome complex IEA GO:0000502 proteasome complex ISS GO:0005622 intracellular IEA GO:0005625 soluble fraction IEA GO:0005626 insoluble fraction IEA GO:0005634 nucleus IDA GO:0005634 nucleus IEA GO:0005737 cytoplasm IDA GO:0005737 cytoplasm IEA GO:0005737 cytoplasm TAS GO:0005819 spindle IEA GO:0005829 cytosol TAS GO:0005856 cytoskeleton TAS GO:0005886 plasma membrane IEA GO:0009986 cell surface IDA GO:0030018 Z disc IEA GO:0043292 contractile fiber IEA molecular_function GO:0005515 protein binding IPI GO:0008426 protein kinase C inhibitor activity IEA GO:0008426 protein kinase C inhibitor activity ISS GO:0043130 ubiquitin binding IEA GO:0043130 ubiquitin binding ISS GO:0072568 protein kinase C delta binding IEA GO:0072568 protein kinase C delta binding ISS

Protein-protein interaction details for HSPB1 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID HSPB8 Two-hybrid physical 14594798 MAGED1 Affinity Capture-MS physical 17353931 ILK Affinity Capture-MS physical 17353931 HSPB8 Affinity Capture-Western physical 15122253 IGSF21 Two-hybrid physical 16169070 PPA1 Two-hybrid physical 16169070 MED31 Two-hybrid physical 16169070 C7orf64 Two-hybrid physical 16169070 C1orf103 Two-hybrid physical 16169070 TP53 Two-hybrid physical 16169070 AKT1 Affinity Capture-Western physical 11042204 MAPKAPK2 Affinity Capture-Western physical 11042204 CRYAB Co-purification physical 1560006 CRYAB Reconstituted Complex physical 1560006 CYCS Affinity Capture-Western physical 11784858 MAPKAPK5 Biochemical Activity physical 9628874 CRYAA Two-hybrid physical 11700327 CRYAB Two-hybrid physical 11700327 CRYBB2 Two-hybrid physical 11700327 CRYAA Affinity Capture-Western physical 11700327 CRYAB Affinity Capture-Western physical 11700327 CRYBB2 Affinity Capture-Western physical 11700327 HNRNPD Affinity Capture-MS physical 18573886 HNRNPD Affinity Capture-Western physical 18573886 HNRNPD FRET physical 18573886 TGFB1I1 Two-hybrid physical 11546764 TGFB1I1 Affinity Capture-Western physical 11546764 TGFB1I1 Affinity Capture-Western physical 11546764 USP38 Affinity Capture-MS physical 19615732 USP1 Affinity Capture-MS physical 19615732 DMWD Affinity Capture-MS physical 19615732 SRRM2 Affinity Capture-MS physical 16159877 PRKD1 Reconstituted Complex physical 15728188 PRKD1 Biochemical Activity physical 15728188 UBC Affinity Capture-MS physical 16196087 MYC Affinity Capture-MS physical 17314511 G6PD Affinity Capture-Western physical 21157431 G6PD Affinity Capture-Western physical 21157431 GATA1 Biochemical Activity physical 20410505 GATA1 Affinity Capture-Western physical 20410505 GATA1 Two-hybrid physical 20410505 GATA1 Affinity Capture-Western physical 20410505 UCHL5 Reconstituted Complex physical 21800051 YWHAQ Affinity Capture-MS physical 20618440 MME Affinity Capture-MS physical 17342744 MME Affinity Capture-Western physical 17342744 MME Affinity Capture-Western physical 17342744 UBE2I Affinity Capture-Western physical 19597476 HSF1 Affinity Capture-Western physical 19597476 HSF1 Affinity Capture-Western physical 19597476 HSF1 Co-localization physical 19597476 TP53 Affinity Capture-Western physical 17184779 HNRNPD Co-fractionation physical 21245386 HNRNPD Affinity Capture-Western physical 21245386 HNRNPD FRET physical 21245386 TNF Affinity Capture-RNA physical 21245386 SUMO1 Reconstituted Complex physical 19596686 UNG Reconstituted Complex physical 10629618 UNG Affinity Capture-Western physical 10629618 RPS6KA5 Biochemical Activity physical 9873047 UBC Affinity Capture-MS physical 22178446 UBC Affinity Capture-Western physical 22178446 UBC Co-purification physical 17623298 UBC Affinity Capture-MS physical 18781797 UBC Affinity Capture-MS physical 21987572