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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for HSP90AA1 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000086 G2/M transition of mitotic cell cycle TAS GO:0000278 mitotic cell cycle TAS GO:0006200 ATP catabolic process IDA GO:0006457 protein folding IEA GO:0006839 mitochondrial transport TAS GO:0006950 response to stress IEA GO:0006986 response to unfolded protein NAS GO:0007165 signal transduction NAS GO:0007411 axon guidance TAS GO:0034619 cellular chaperone-mediated protein complex assembly IDA GO:0042026 protein refolding TAS GO:0045040 protein import into mitochondrial outer membrane IDA GO:0045429 positive regulation of nitric oxide biosynthetic process ISS GO:0046209 nitric oxide metabolic process TAS GO:0050999 regulation of nitric-oxide synthase activity TAS cellular_component GO:0005622 intracellular IEA GO:0005737 cytoplasm IEA GO:0005829 cytosol NAS GO:0005829 cytosol TAS GO:0005886 plasma membrane TAS GO:0042470 melanosome IEA molecular_function GO:0000166 nucleotide binding TAS GO:0004674 protein serine/threonine kinase activity TAS GO:0005515 protein binding IPI GO:0005524 ATP binding IEA GO:0005524 ATP binding TAS GO:0016887 ATPase activity IDA GO:0030235 nitric-oxide synthase regulator activity IDA GO:0030911 TPR domain binding IDA GO:0030911 TPR domain binding TAS GO:0042802 identical protein binding IPI GO:0042803 protein homodimerization activity TAS GO:0051082 unfolded protein binding IEA

Protein-protein interaction details for HSP90AA1 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID LSM1 Two-hybrid physical 15231747 AR Affinity Capture-Western physical 1540595 FANCA Two-hybrid physical 14499622 FANCC Two-hybrid physical 14499622 SMYD3 Affinity Capture-Western physical 15235609 SMYD3 Affinity Capture-Western physical 15235609 CDC37 Co-crystal Structure physical 14718169 STARD13 Two-hybrid physical 14697242 BAG4 Affinity Capture-Western physical 14559896 CHTF18 Affinity Capture-MS physical 12930902 NOS3 Affinity Capture-Western physical 12676772 NOS3 Affinity Capture-Western physical 12676772 GUCY1B3 Reconstituted Complex physical 12676772 GUCY1B3 Affinity Capture-Western physical 12676772 GUCY1B3 Affinity Capture-Western physical 12676772 HCFC1 Affinity Capture-MS physical 12670868 MYC Affinity Capture-Western physical 12644583 RALBP1 Affinity Capture-Western physical 12621024 HSF1 Affinity Capture-Western physical 12621024 TUBA1A Affinity Capture-Western physical 12621024 ESR1 Reconstituted Complex physical 9222609 FES Reconstituted Complex physical 9222609 HSF1 Reconstituted Complex physical 9222609 CSNK2A1 Reconstituted Complex physical 7794926 CSNK2A2 Reconstituted Complex physical 7794926 TERT Affinity Capture-Western physical 12586360 AKT1 Affinity Capture-Western physical 12586360 HSP90AA1 Two-hybrid physical 16169070 RPS3A Two-hybrid physical 16169070 NR3C1 Co-localization physical 10066374 TP53 Affinity Capture-Western physical 12427754 DAP3 Reconstituted Complex physical 10903152 DAP3 Affinity Capture-Western physical 10903152 NR3C1 Affinity Capture-Western physical 10903152 SIM1 Reconstituted Complex physical 9020169 MYOD1 Reconstituted Complex physical 1406681 STIP1 Reconstituted Complex physical 10786835 PIM1 Affinity Capture-Western physical 11237709 PIM1 Affinity Capture-MS physical 11237709 PIM1 Affinity Capture-Western physical 11237709 ESR1 Affinity Capture-Western physical 11911945 HSPA8 Affinity Capture-Western physical 9269769 EPRS Two-hybrid physical 10913161 EPRS Affinity Capture-Western physical 10913161 EPRS Reconstituted Complex physical 10913161 EPRS Co-purification physical 10913161 STK11 Affinity Capture-Western physical 12489981 STK11 Reconstituted Complex physical 12489981 NR3C1 Reconstituted Complex physical 12093808 HSPA1A Reconstituted Complex physical 12093808 SGTA Far Western physical 12482202 RAF1 Affinity Capture-Western physical 8408024 APAF1 Affinity Capture-Western physical 10934467 CUL4A Affinity Capture-MS physical 12481031 STAT3 Affinity Capture-Western physical 12559950 AKT1 Affinity Capture-Western physical 15843522 FNIP1 Affinity Capture-MS physical 17028174 TERT Affinity Capture-Western physical 15843522 STIP1 Affinity Capture-Western physical 9452498 NR3C1 Reconstituted Complex physical 9334248 ERN1 Affinity Capture-Western physical 12446770 ERN1 Reconstituted Complex physical 12446770 EIF2AK3 Affinity Capture-Western physical 12446770 AKT1 Affinity Capture-Western physical 10995457 IRS4 Affinity Capture-MS physical 11912194 AIP Affinity Capture-Western physical 11013261 ARNT Affinity Capture-Western physical 11013261 ARNTL Reconstituted Complex physical 9079689 HIF1A Reconstituted Complex physical 9079689 NPAS2 Reconstituted Complex physical 9079689 TP53 Affinity Capture-Western physical 11297531 NR3C1 Affinity Capture-Western physical 8898375 NR3C1 Affinity Capture-Western physical 8645634 NR3C1 Affinity Capture-Western physical 8621522 SRC Affinity Capture-Western physical 1310678 NOS3 Affinity Capture-Western physical 11744239 NOS3 Reconstituted Complex physical 11744239 NOS3 Affinity Capture-Western physical 12124224 AHR Affinity Capture-Western physical 9083006 CDC37 Reconstituted Complex physical 9685350 PPARA Affinity Capture-Western physical 12482853 PPARA Reconstituted Complex physical 12482853 FKBP5 Affinity Capture-Western physical 9001212 FKBP5 Reconstituted Complex physical 9001212 AR Reconstituted Complex physical 1525041 GNA12 Affinity Capture-Western physical 11598136 GNA12 Two-hybrid physical 11598136 TP53 Affinity Capture-Western physical 11507088 EIF2AK2 Affinity Capture-Western physical 11447118 AHSA1 Affinity Capture-Western physical 12504007 AHSA2 Affinity Capture-Western physical 12504007 AHSA2 Reconstituted Complex physical 12504007 AHSA1 Reconstituted Complex physical 12504007 AHSA1 Two-hybrid physical 12504007 PTGES3 Reconstituted Complex physical 11812147 ERBB2 Affinity Capture-Western physical 11071886 RAF1 Affinity Capture-Western physical 19011619 ERBB2 Affinity Capture-Western physical 18655187 TGFBR1 Reconstituted Complex physical 18591668 TGFBR2 Reconstituted Complex physical 18591668 TJP1 Reconstituted Complex physical 18591668 TGFBR1 Affinity Capture-Western physical 18591668 TGFBR2 Affinity Capture-Western physical 18591668 TGFBR1 Affinity Capture-Western physical 18591668 TGFBR2 Affinity Capture-Western physical 18591668 FLT3 Affinity Capture-Western physical 18394702 GUCY1A2 Affinity Capture-Western physical 17873020 AR Affinity Capture-Western physical 17974989 DAPK1 Affinity Capture-Western physical 17324930 STUB1 Affinity Capture-Western physical 17324930 MCF2 Reconstituted Complex physical 17178836 RAF1 Affinity Capture-Western physical 20159553 ERBB2 Affinity Capture-Western physical 20159553 AHSA1 Affinity Capture-Western physical 20159553 PTGES3 Affinity Capture-Western physical 20159553 CDC37 Affinity Capture-Western physical 20159553 STIP1 Affinity Capture-Western physical 20159553 RIPK1 Affinity Capture-Western physical 16968706 MST1R Affinity Capture-Western physical 16740632 VCP Affinity Capture-Western physical 16621797 RAF1 Affinity Capture-Western physical 16504566 HDAC6 Affinity Capture-Western physical 19158084 RPS3 Reconstituted Complex physical 16314389 RPS3 Affinity Capture-Western physical 16314389 HSPA4 Affinity Capture-Western physical 16314389 RPS6 Affinity Capture-Western physical 16314389 STUB1 Reconstituted Complex physical 16307917 UBE2N Reconstituted Complex physical 16307917 UBC Affinity Capture-Western physical 16196087 SIN3A Affinity Capture-Western physical 17210713 PAK1 Two-hybrid physical 20936779 JUN Two-hybrid physical 20936779 PRKCZ Two-hybrid physical 20936779 ESR1 Affinity Capture-Western physical 16037132 COPS3 Affinity Capture-MS physical 16036220 HIF1A Affinity Capture-Western physical 16951198 STUB1 Affinity Capture-MS physical 15538384 STUB1 Affinity Capture-Western physical 15538384 ESR1 Affinity Capture-Western physical 15538384 PPP5C Affinity Capture-MS physical 15383005 CDK11B Affinity Capture-MS physical 15344906 C8orf41 Affinity Capture-MS physical 20801936 HDAC6 Affinity Capture-Western physical 18591380 HIF1A Affinity Capture-Western physical 16507982 HIF1A Affinity Capture-Western physical 15147973 MGMT Affinity Capture-MS physical 16226712 MGMT Affinity Capture-Western physical 16226712 SP1 Affinity Capture-Western physical 16118214 SP1 Reconstituted Complex physical 16118214 NR3C1 Affinity Capture-Western physical 16087666 HIF1A Affinity Capture-Western physical 14726529 STK11 Affinity Capture-Western physical 14668798 FKBP5 Reconstituted Complex physical 21170051 STIP1 Reconstituted Complex physical 21170051 FKBP4 Reconstituted Complex physical 21170051 AIP Reconstituted Complex physical 21170051 ABL1 Affinity Capture-Western physical 15937340 HDAC6 Affinity Capture-Western physical 15937340 HDAC6 Affinity Capture-Western physical 15916966 PTGES3 Affinity Capture-Western physical 15916966 NR3C1 Affinity Capture-Western physical 15916966 TSSK6 Affinity Capture-MS physical 15870294 UBC Affinity Capture-Western physical 12821935 HIST3H3 Co-purification physical 20953179 HIST3H3 Affinity Capture-MS physical 20953179 AKT1 Affinity Capture-Western physical 12176997 CDC37 Affinity Capture-Western physical 12176997 VEGFA Affinity Capture-Western physical 18211808 SMYD2 Affinity Capture-Western physical 18065756 EGFR Affinity Capture-Western physical 12006493 ERBB2 Affinity Capture-Western physical 12006493 PRMT5 Affinity Capture-Western physical 17409432 RAF1 Affinity Capture-Western physical 17409432 RAF1 Affinity Capture-Western physical 17699868 ESR1 Affinity Capture-Western physical 17699868 STUB1 Affinity Capture-Western physical 11146632 CFTR Reconstituted Complex physical 10982807 TP53 Affinity Capture-Western physical 10557093 ESR1 Affinity Capture-Western physical 20353944 ESR2 Affinity Capture-Western physical 20353944 JAK2 Affinity Capture-Western physical 20353823 HSP90AB1 Affinity Capture-Western physical 20353823 STUB1 Affinity Capture-Western physical 19196961 HES1 Affinity Capture-MS physical 18550849 UBC Affinity Capture-MS physical 16335966 RAF1 Affinity Capture-Western physical 20039095 HSPA8 Affinity Capture-Western physical 20039095 PTGES3 Affinity Capture-Western physical 20039095 CUL5 Affinity Capture-MS physical 19933325 CUL5 Affinity Capture-Western physical 19933325 ERBB2 Affinity Capture-Western physical 17239458 PI4K2B Affinity Capture-Western physical 21330372 PI4K2A Affinity Capture-Western physical 21330372 H2AFX Affinity Capture-MS physical 20000738 STUB1 Affinity Capture-Western physical 17317785 STUB1 Affinity Capture-Western physical 17317785 APP Affinity Capture-Western physical 17317785 STUB1 Reconstituted Complex physical 21454478 AKT1 Affinity Capture-Western physical 21767636 FGFR3 Affinity Capture-MS physical 21487019 UBC Affinity Capture-MS physical 16196087 HIF1A Affinity Capture-Western physical 17237281 USP50 Two-hybrid physical 20930503 RARRES3 Affinity Capture-Western physical 19234166 RARRES3 Affinity Capture-Western physical 19234166 STUB1 Reconstituted Complex physical 20618441 CDK5R1 Reconstituted Complex physical 20618441 STUB1 Reconstituted Complex physical 20146531 SENP3 Affinity Capture-Western physical 20924358 SENP3 Affinity Capture-Western physical 20924358 ERBB2 Affinity Capture-Western physical 21503962 ESR1 Affinity Capture-Western physical 21503962 PRKAA1 Affinity Capture-MS physical 16306228 EIF2C4 Affinity Capture-MS physical 19167051 CD4 Affinity Capture-MS physical 15047060 BCR Affinity Capture-Western physical 21248063 ABL1 Affinity Capture-Western physical 21248063 HIF1A Affinity Capture-Western physical 20724477 HIF1A Affinity Capture-Western physical 20724477 MAP3K3 Affinity Capture-Western physical 19560753 MAP3K3 Affinity Capture-Western physical 19560753 STUB1 Biochemical Activity physical 19913553 HDAC5 Affinity Capture-MS physical 21081666 AR Affinity Capture-Western physical 19706771 MYOCD Affinity Capture-Western physical 19237536 STUB1 Co-fractionation physical 20704274 STUB1 Biochemical Activity physical 20704274 STUB1 Reconstituted Complex physical 20704274 STIP1 Reconstituted Complex physical 20704274 UBC Affinity Capture-Western physical 18042044 MDM2 Affinity Capture-Western physical 20540933 STUB1 Affinity Capture-Western physical 18784277 DYRK2 Affinity Capture-MS physical 19287380 CDKN2A Affinity Capture-MS physical 17955473 STK11 Affinity Capture-MS physical 14676191 PRKCI Affinity Capture-MS physical 14676191 LRRK2 Affinity Capture-Western physical 19536328 LRRK2 Affinity Capture-Western physical 19536328 KEAP1 Affinity Capture-Western physical 20864537 KEAP1 Affinity Capture-Western physical 20864537 HIF1A Affinity Capture-Western physical 21413014 FBXW8 Affinity Capture-MS physical 21946088 BCR Affinity Capture-Western physical 20675402 ABL1 Affinity Capture-Western physical 20675402 HLA-DRA Affinity Capture-MS physical 20458337 HLA-DRB1 Affinity Capture-MS physical 20458337 HLA-DRB3 Affinity Capture-MS physical 20458337 HLA-DRB4 Affinity Capture-MS physical 20458337 HLA-DRB5 Affinity Capture-MS physical 20458337 MAP3K7 Affinity Capture-Western physical 19026643 PSMA3 Affinity Capture-MS physical 22079093 SUMO1 Affinity Capture-MS physical 19596686 GBA Affinity Capture-Western physical 22160715 EIF2AK1 Reconstituted Complex physical 11036079 SVIL Two-hybrid physical 20309963 CALM1 Reconstituted Complex physical 7887964 PPP5C Reconstituted Complex physical 9195923 NR3C1 Reconstituted Complex physical 9195923 TERT Reconstituted Complex physical 10197982 UBC Affinity Capture-MS physical 22178446 HSF1 Affinity Capture-Western physical 11583998 NOS3 Two-hybrid physical 11988487 NOS3 Reconstituted Complex physical 11988487 NTRK1 Affinity Capture-Western physical 20663926 STUB1 Affinity Capture-Western physical 12574167 UBC Affinity Capture-MS physical 18781797 FKBPL Affinity Capture-Western physical 15664193 UBC Affinity Capture-MS physical 21987572 CDKN1A Affinity Capture-Western physical 15664193 FKBPL Affinity Capture-Western physical 15664193 AR Reconstituted Complex physical 21157430 UBC Affinity Capture-Western physical 21984809 BECN1 Affinity Capture-Western physical 21543763 BCL2 Affinity Capture-Western physical 21543763 BCL2 Affinity Capture-Western physical 21543763 CHEK1 Affinity Capture-Western physical 21566061 ATR Affinity Capture-Western physical 21566061 ATR Affinity Capture-Western physical 21566061 REV1 Affinity Capture-Western physical 21690293 REV1 Affinity Capture-Western physical 21690293