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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for ICAM1 (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0001541ovarian follicle developmentIEA
GO:0001910regulation of leukocyte mediated cytotoxicityTAS
GO:0001975response to amphetamineIEA
GO:0002291T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cellIMP
GO:0002457T cell antigen processing and presentationIEA
GO:0002693positive regulation of cellular extravasationIMP
GO:0007155cell adhesionIDA
GO:0007157heterophilic cell-cell adhesionTAS
GO:0007159leukocyte cell-cell adhesionIMP
GO:0007569cell agingIEA
GO:0008360regulation of cell shapeIEA
GO:0010212response to ionizing radiationIEA
GO:0010477response to sulfur dioxideIEA
GO:0014070response to organic cyclic compoundIEA
GO:0016337cell-cell adhesionIEA
GO:0019221cytokine-mediated signaling pathwayTAS
GO:0022614membrane to membrane dockingIEP
GO:0030155regulation of cell adhesionIEA
GO:0031669cellular response to nutrient levelsIEA
GO:0033627cell adhesion mediated by integrinIEA
GO:0034698response to gonadotropin stimulusIEA
GO:0042493response to drugIEA
GO:0043200response to amino acid stimulusIEA
GO:0044419interspecies interaction between organismsIEA
GO:0045429positive regulation of nitric oxide biosynthetic processIEA
GO:0045471response to ethanolIEA
GO:0045907positive regulation of vasoconstrictionIEA
GO:0046688response to copper ionIEA
GO:0046813virion attachment, binding of host cell surface receptorIDA
GO:0050776regulation of immune responseTAS
GO:0050900leukocyte migrationIEP
GO:0051092positive regulation of NF-kappaB transcription factor activityIEA
GO:0051856adhesion to symbiontIDA
GO:0051926negative regulation of calcium ion transportIEA
GO:0060333interferon-gamma-mediated signaling pathwayTAS
GO:0071222cellular response to lipopolysaccharideIEA
GO:0071312cellular response to alkaloidIEA
GO:0071333cellular response to glucose stimulusIEA
GO:0071347cellular response to interleukin-1IEA
GO:0071356cellular response to tumor necrosis factorIEA
GO:0071456cellular response to hypoxiaIEA
cellular_component
GO:0001772immunological synapseIEA
GO:0005615extracellular spaceIDA
GO:0005886plasma membraneTAS
GO:0005887integral to plasma membraneTAS
GO:0009897external side of plasma membraneIEA
GO:0016020membraneIEA
molecular_function
GO:0004872receptor activityIEA
GO:0004888transmembrane signaling receptor activityTAS
GO:0005178integrin bindingIPI
GO:0005515protein bindingIPI
GO:0043498cell surface bindingIEA

Protein-protein interaction details for ICAM1 (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
ITGB2Reconstituted Complexphysical10352278
EZRReconstituted Complexphysical9705328
EZRAffinity Capture-Westernphysical9705328
ITGALReconstituted Complexphysical11279101
ITGB2Reconstituted Complexphysical11279101
IL2RAAffinity Capture-Westernphysical1976256
ITGAMReconstituted Complexphysical12208882
ITGALCo-crystal Structurephysical12526797
ITGALReconstituted Complexphysical11786177
ITGB2Reconstituted Complexphysical7642561
ITGB2Reconstituted Complexphysical20187292