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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for TMEM173 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0002218 activation of innate immune response IMP GO:0002230 positive regulation of defense response to virus by host IMP GO:0006915 apoptosis IEA GO:0032092 positive regulation of protein binding IDA GO:0032608 interferon-beta production IDA GO:0032608 interferon-beta production IMP GO:0033160 positive regulation of protein import into nucleus, translocation IDA GO:0042993 positive regulation of transcription factor import into nucleus IDA GO:0045087 innate immune response IDA GO:0045087 innate immune response IMP GO:0045944 positive regulation of transcription from RNA polymerase II promoter IDA GO:0051607 defense response to virus IDA GO:0071360 cellular response to exogenous dsRNA IMP cellular_component GO:0005737 cytoplasm IEA GO:0005739 mitochondrion IEA GO:0005741 mitochondrial outer membrane IDA GO:0005783 endoplasmic reticulum IEA GO:0005789 endoplasmic reticulum membrane IDA GO:0005886 plasma membrane IEA GO:0016021 integral to membrane IEA GO:0048471 perinuclear region of cytoplasm ISS molecular_function GO:0005515 protein binding IPI GO:0008134 transcription factor binding IDA GO:0019901 protein kinase binding IDA GO:0019901 protein kinase binding IPI GO:0031625 ubiquitin protein ligase binding IEA GO:0042803 protein homodimerization activity IDA

Protein-protein interaction details for TMEM173 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID TRIM56 Affinity Capture-Western physical 21074459 UBC Affinity Capture-Western physical 21074459 TMEM173 Affinity Capture-Western physical 21074459 TBK1 Affinity Capture-Western physical 21074459 RNF5 Affinity Capture-Western physical 19285439 UBC Affinity Capture-Western physical 19285439 ABCC1 Affinity Capture-MS physical 21903422 IRAK1 Affinity Capture-MS physical 21903422 C19orf6 Affinity Capture-MS physical 21903422 SEC61A1 Affinity Capture-MS physical 21903422 TBK1 Affinity Capture-MS physical 21903422 SLC39A14 Affinity Capture-MS physical 21903422 ACSL3 Affinity Capture-MS physical 21903422 CCDC47 Affinity Capture-MS physical 21903422 CLPTM1L Affinity Capture-MS physical 21903422 CNNM3 Affinity Capture-MS physical 21903422 DDOST Affinity Capture-MS physical 21903422 GLMN Affinity Capture-MS physical 21903422 HM13 Affinity Capture-MS physical 21903422 MBOAT7 Affinity Capture-MS physical 21903422 NPC1 Affinity Capture-MS physical 21903422 RNF160 Affinity Capture-MS physical 21903422 SGPL1 Affinity Capture-MS physical 21903422 STT3A Affinity Capture-MS physical 21903422 STT3B Affinity Capture-MS physical 21903422 SURF4 Affinity Capture-MS physical 21903422 YIPF5 Affinity Capture-MS physical 21903422 CCDC47 Reconstituted Complex physical 21903422 DDOST Reconstituted Complex physical 21903422 IRAK1 Reconstituted Complex physical 21903422 MBOAT7 Reconstituted Complex physical 21903422 RNF160 Reconstituted Complex physical 21903422 SGPL1 Reconstituted Complex physical 21903422 STT3A Reconstituted Complex physical 21903422 SURF4 Reconstituted Complex physical 21903422