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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for IL1R1 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0006955 immune response TAS GO:0007165 signal transduction IEA GO:0007166 cell surface receptor linked signaling pathway TAS GO:0030728 ovulation IEA GO:0045087 innate immune response IEA GO:0070498 interleukin-1-mediated signaling pathway IDA GO:0070498 interleukin-1-mediated signaling pathway TAS GO:0070555 response to interleukin-1 IDA GO:0071731 response to nitric oxide IEA cellular_component GO:0005886 plasma membrane TAS GO:0005887 integral to plasma membrane TAS GO:0009986 cell surface IEA GO:0016020 membrane IDA GO:0016020 membrane IEA GO:0016021 integral to membrane IEA GO:0031224 intrinsic to membrane IEA molecular_function GO:0002020 protease binding IEA GO:0004871 signal transducer activity IEA GO:0004872 receptor activity IEA GO:0004888 transmembrane signaling receptor activity IEA GO:0004908 interleukin-1 receptor activity IDA GO:0004909 interleukin-1, Type I, activating receptor activity IEA GO:0005161 platelet-derived growth factor receptor binding IPI GO:0005515 protein binding IPI

Protein-protein interaction details for IL1R1 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID SIGIRR Affinity Capture-Western physical 12925853 IL1RAP Affinity Capture-Western physical 9371760 IL1RAP Affinity Capture-Western physical 9371760 PIK3R1 Affinity Capture-Western physical 9360994 PIK3R1 Affinity Capture-Western physical 9360994 TOLLIP Affinity Capture-Western physical 10854325 MYD88 Affinity Capture-Western physical 10854325 IRAK2 Affinity Capture-Western physical 9374458 MYD88 Affinity Capture-Western physical 9374458 IL1B Reconstituted Complex physical 7878046 IL1RN Co-crystal Structure physical 9062194 UBC Affinity Capture-Western physical 17113392 TOLLIP Affinity Capture-Western physical 17113392 TOLLIP Affinity Capture-Western physical 17113392 TOM1 Affinity Capture-Western physical 17113392