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Gene
Protein
Transcript
Promoter
Expression
GO/PPI
PubMed
Cross reference
Gene Ontology information for IL12B (
Homo sapiens
)
(Information is obtained from AmiGO)
ID
Term
Evidence
biological_process
GO:0001916
positive regulation of T cell mediated cytotoxicity
ISS
GO:0002230
positive regulation of defense response to virus by host
IDA
GO:0002230
positive regulation of defense response to virus by host
ISS
GO:0002827
positive regulation of T-helper 1 type immune response
IDA
GO:0002827
positive regulation of T-helper 1 type immune response
ISS
GO:0002860
positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target
IDA
GO:0002862
negative regulation of inflammatory response to antigenic stimulus
IEA
GO:0007050
cell cycle arrest
IDA
GO:0007165
signal transduction
TAS
GO:0010224
response to UV-B
IDA
GO:0010535
positive regulation of activation of JAK2 kinase activity
IDA
GO:0016477
cell migration
IDA
GO:0019953
sexual reproduction
TAS
GO:0030101
natural killer cell activation
IDA
GO:0032693
negative regulation of interleukin-10 production
IMP
GO:0032700
negative regulation of interleukin-17 production
IDA
GO:0032725
positive regulation of granulocyte macrophage colony-stimulating factor production
IDA
GO:0032729
positive regulation of interferon-gamma production
IDA
GO:0032733
positive regulation of interleukin-10 production
IDA
GO:0032733
positive regulation of interleukin-10 production
TAS
GO:0032735
positive regulation of interleukin-12 production
IDA
GO:0032740
positive regulation of interleukin-17 production
IDA
GO:0032760
positive regulation of tumor necrosis factor production
IMP
GO:0032816
positive regulation of natural killer cell activation
IC
GO:0032816
positive regulation of natural killer cell activation
IDA
GO:0032819
positive regulation of natural killer cell proliferation
IDA
GO:0034105
positive regulation of tissue remodeling
IC
GO:0034393
positive regulation of smooth muscle cell apoptosis
IDA
GO:0042035
regulation of cytokine biosynthetic process
TAS
GO:0042088
T-helper 1 type immune response
TAS
GO:0042093
T-helper cell differentiation
IDA
GO:0042095
interferon-gamma biosynthetic process
TAS
GO:0042102
positive regulation of T cell proliferation
IDA
GO:0042104
positive regulation of activated T cell proliferation
IDA
GO:0042346
positive regulation of NF-kappaB import into nucleus
TAS
GO:0042510
regulation of tyrosine phosphorylation of Stat1 protein
IDA
GO:0042517
positive regulation of tyrosine phosphorylation of Stat3 protein
IDA
GO:0042520
positive regulation of tyrosine phosphorylation of Stat4 protein
IDA
GO:0042523
positive regulation of tyrosine phosphorylation of Stat5 protein
IDA
GO:0042832
defense response to protozoan
IEA
GO:0043382
positive regulation of memory T cell differentiation
ISS
GO:0044130
negative regulation of growth of symbiont in host
IEA
GO:0045078
positive regulation of interferon-gamma biosynthetic process
TAS
GO:0045672
positive regulation of osteoclast differentiation
IDA
GO:0045785
positive regulation of cell adhesion
IDA
GO:0048662
negative regulation of smooth muscle cell proliferation
IDA
GO:0050671
positive regulation of lymphocyte proliferation
IDA
GO:0050729
positive regulation of inflammatory response
IC
GO:0050829
defense response to Gram-negative bacterium
IDA
GO:0051135
positive regulation of NK T cell activation
IC
GO:0051135
positive regulation of NK T cell activation
IDA
GO:0051142
positive regulation of NK T cell proliferation
IDA
GO:0051607
defense response to virus
IEA
GO:0071222
cellular response to lipopolysaccharide
IEA
GO:0071346
cellular response to interferon-gamma
IEA
GO:2000318
positive regulation of T-helper 17 type immune response
ISS
GO:2000330
positive regulation of T-helper 17 cell lineage commitment
ISS
cellular_component
GO:0005576
extracellular region
IEA
GO:0005615
extracellular space
TAS
GO:0005737
cytoplasm
IEA
GO:0016020
membrane
IEA
GO:0043514
interleukin-12 complex
IDA
GO:0070743
interleukin-23 complex
IDA
molecular_function
GO:0004871
signal transducer activity
TAS
GO:0004896
cytokine receptor activity
IEA
GO:0005125
cytokine activity
IDA
GO:0005143
interleukin-12 receptor binding
TAS
GO:0005515
protein binding
IPI
GO:0008083
growth factor activity
IDA
GO:0042164
interleukin-12 alpha subunit binding
IEA
GO:0042802
identical protein binding
IPI
GO:0042803
protein homodimerization activity
IEA
GO:0045519
interleukin-23 receptor binding
IDA
GO:0046982
protein heterodimerization activity
IPI
Protein-protein interaction details for IL12B (
Homo sapiens
)
(Information is obtained from BioGRID)
Interacting human protein
Experiment
Type
PubMed ID
IL12A
Co-crystal Structure
physical
10899108
IL23A
Affinity Capture-Western
physical
11114383
IL23A
Affinity Capture-Western
physical
11114383