Database of mammalian genes
Home

Home Search Browse Statistics User guide FAQs Links Questions Contribute Download

Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for IRF6 (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0006351transcription, DNA-dependentISS
GO:0007050cell cycle arrestIDA
GO:0008285negative regulation of cell proliferationIDA
GO:0008285negative regulation of cell proliferationIEA
GO:0019221cytokine-mediated signaling pathwayTAS
GO:0030216keratinocyte differentiationIEA
GO:0043588skin developmentIEA
GO:0043616keratinocyte proliferationIEA
GO:0045893positive regulation of transcription, DNA-dependentIEA
GO:0045893positive regulation of transcription, DNA-dependentISS
GO:0048468cell developmentIEA
GO:0060333interferon-gamma-mediated signaling pathwayTAS
GO:0060337type I interferon-mediated signaling pathwayTAS
GO:0060644mammary gland epithelial cell differentiationIEA
GO:0060644mammary gland epithelial cell differentiationISS
cellular_component
GO:0005634nucleusIEA
GO:0005737cytoplasmIDA
GO:0005829cytosolTAS
molecular_function
GO:0000975regulatory region DNA bindingIEA
GO:0003677DNA bindingIEA
GO:0003677DNA bindingISS
GO:0003700sequence-specific DNA binding transcription factor activityIEA
GO:0003700sequence-specific DNA binding transcription factor activityISS
GO:0005515protein bindingIPI

Protein-protein interaction details for IRF6 (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
LBPReconstituted Complexphysical11544322
TLX2Two-hybridphysical20211142
RFX3Two-hybridphysical20211142
ZBTB3Two-hybridphysical20211142
BNC2Affinity Capture-MSphysical21903422
IRF5Affinity Capture-MSphysical21903422
IRF8Affinity Capture-MSphysical21903422
IRF8Affinity Capture-MSphysical21903422
IRF8Reconstituted Complexphysical21903422
IRF8Reconstituted Complexphysical21903422