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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for IRF7 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000122 negative regulation of transcription from RNA polymerase II promoter TAS GO:0002756 MyD88-independent toll-like receptor signaling pathway TAS GO:0006366 transcription from RNA polymerase II promoter TAS GO:0008063 Toll signaling pathway TAS GO:0009615 response to virus IEA GO:0016064 immunoglobulin mediated immune response IEA GO:0019221 cytokine-mediated signaling pathway TAS GO:0032727 positive regulation of interferon-alpha production IDA GO:0034138 toll-like receptor 3 signaling pathway TAS GO:0034142 toll-like receptor 4 signaling pathway TAS GO:0044419 interspecies interaction between organisms IEA GO:0045087 innate immune response TAS GO:0045351 type I interferon biosynthetic process IEA GO:0045944 positive regulation of transcription from RNA polymerase II promoter IDA GO:0060333 interferon-gamma-mediated signaling pathway TAS GO:0060337 type I interferon-mediated signaling pathway TAS cellular_component GO:0005634 nucleus IEA GO:0005654 nucleoplasm TAS GO:0005737 cytoplasm IEA GO:0005829 cytosol TAS GO:0005886 plasma membrane TAS GO:0010008 endosome membrane TAS molecular_function GO:0000975 regulatory region DNA binding IEA GO:0003700 sequence-specific DNA binding transcription factor activity IEA GO:0005515 protein binding IPI

Protein-protein interaction details for IRF7 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID IRF3 Reconstituted Complex physical 11162841 IRF7 Reconstituted Complex physical 11162841 IRF3 Affinity Capture-Western physical 11162841 TANK Two-hybrid physical 17823124 TANK Affinity Capture-Western physical 17823124 ALK Affinity Capture-MS physical 14968112 MYD88 Affinity Capture-Western physical 16484229 MYD88 Two-hybrid physical 15361868 MYD88 Affinity Capture-Western physical 15361868 MYD88 FRET physical 15361868 UBC Affinity Capture-Western physical 15361868 TRAF6 Affinity Capture-Western physical 15361868 FADD Affinity Capture-Western physical 21183682 UBC Affinity Capture-Western physical 21183682 TRAF6 Affinity Capture-Western physical 21183682 UBC Affinity Capture-Western physical 19285439 TNFAIP3 Affinity Capture-Western physical 20392859 TNFAIP3 Affinity Capture-Western physical 20392859 UBC Affinity Capture-Western physical 20392859 UBC Affinity Capture-Western physical 20668674 TRIM21 Affinity Capture-Western physical 20668674 UBC Affinity Capture-Western physical 20668674 TRAF6 Affinity Capture-Western physical 22095711 UBC Affinity Capture-Western physical 22095711 ARAF Affinity Capture-MS physical 21903422 CCDC47 Affinity Capture-MS physical 21903422 IRAK1 Affinity Capture-MS physical 21903422 TRMT2A Affinity Capture-MS physical 21903422 RNF160 Affinity Capture-MS physical 21903422 AIP Affinity Capture-MS physical 21903422 HACE1 Affinity Capture-MS physical 21903422 IQSEC1 Affinity Capture-MS physical 21903422 P4HA1 Affinity Capture-MS physical 21903422 KIAA1274 Affinity Capture-MS physical 21903422 TLK2 Affinity Capture-MS physical 21903422 TRMT61B Affinity Capture-MS physical 21903422 AIP Reconstituted Complex physical 21903422 ARAF Reconstituted Complex physical 21903422 CCDC47 Reconstituted Complex physical 21903422 IRAK1 Reconstituted Complex physical 21903422 KIAA1274 Reconstituted Complex physical 21903422 RNF160 Reconstituted Complex physical 21903422 TLK2 Reconstituted Complex physical 21903422 TRMT61B Reconstituted Complex physical 21903422 EP300 Reconstituted Complex physical 12604599 CREBBP Reconstituted Complex physical 12604599