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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for ISL1 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000122 negative regulation of transcription from RNA polymerase II promoter ISS GO:0001755 neural crest cell migration IEA GO:0003007 heart morphogenesis IEA GO:0007275 multicellular organismal development IEA GO:0021522 spinal cord motor neuron differentiation ISS GO:0021524 visceral motor neuron differentiation IEA GO:0021559 trigeminal nerve development ISS GO:0021983 pituitary gland development IEA GO:0031016 pancreas development IEA GO:0031016 pancreas development ISS GO:0031103 axon regeneration IEA GO:0031290 retinal ganglion cell axon guidance IEA GO:0032024 positive regulation of insulin secretion IEA GO:0043524 negative regulation of neuron apoptosis ISS GO:0045665 negative regulation of neuron differentiation IEA GO:0045944 positive regulation of transcription from RNA polymerase II promoter IEA GO:0045944 positive regulation of transcription from RNA polymerase II promoter ISS GO:0048663 neuron fate commitment IEA GO:0048665 neuron fate specification ISS GO:0048762 mesenchymal cell differentiation IEA GO:0048762 mesenchymal cell differentiation ISS GO:0048880 sensory system development ISS GO:0048936 peripheral nervous system neuron axonogenesis ISS GO:0060384 innervation ISS cellular_component GO:0005634 nucleus IEA GO:0005634 nucleus NAS GO:0005737 cytoplasm NAS GO:0044424 intracellular part IEA molecular_function GO:0001158 enhancer sequence-specific DNA binding NAS GO:0003682 chromatin binding IEA GO:0003700 sequence-specific DNA binding transcription factor activity IEA GO:0008270 zinc ion binding IEA GO:0043565 sequence-specific DNA binding IEA GO:0046872 metal ion binding IEA

Protein-protein interaction details for ISL1 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID ISL1 Reconstituted Complex physical 9452425 LMX1A Reconstituted Complex physical 9452425 LHX3 Reconstituted Complex physical 9452425 ISL2 Reconstituted Complex physical 9452425 LMO2 Reconstituted Complex physical 9452425 ESR1 Affinity Capture-Western physical 11043578 PECR Reconstituted Complex physical 11043578 ESR1 Reconstituted Complex physical 11043578 NR2F1 Reconstituted Complex physical 11043578 LDB2 Two-hybrid physical 20211142 LHX4 Two-hybrid physical 20211142 SSBP4 Two-hybrid physical 20211142