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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for ITGB1 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000082 G1/S transition of mitotic cell cycle IEA GO:0001701 in utero embryonic development IEA GO:0001708 cell fate specification IEA GO:0001894 tissue homeostasis IEA GO:0002042 cell migration involved in sprouting angiogenesis IEA GO:0006874 cellular calcium ion homeostasis IEA GO:0006968 cellular defense response TAS GO:0007155 cell adhesion IEA GO:0007156 homophilic cell adhesion TAS GO:0007159 leukocyte cell-cell adhesion IDA GO:0007160 cell-matrix adhesion IEA GO:0007160 cell-matrix adhesion IMP GO:0007229 integrin-mediated signaling pathway IEA GO:0007275 multicellular organismal development IEA GO:0007411 axon guidance TAS GO:0007596 blood coagulation TAS GO:0008277 regulation of G-protein coupled receptor protein signaling pathway IEA GO:0008284 positive regulation of cell proliferation IEA GO:0008285 negative regulation of cell proliferation IEA GO:0008354 germ cell migration IEA GO:0010811 positive regulation of cell-substrate adhesion IEA GO:0010976 positive regulation of neuron projection development IEA GO:0014823 response to activity IEA GO:0016477 cell migration TAS GO:0030183 B cell differentiation IC GO:0030335 positive regulation of cell migration IEA GO:0031345 negative regulation of cell projection organization IEA GO:0031667 response to nutrient levels IEA GO:0032594 protein transport within lipid bilayer IEA GO:0033631 cell-cell adhesion mediated by integrin IEP GO:0034329 cell junction assembly TAS GO:0034698 response to gonadotropin stimulus IEA GO:0042493 response to drug IEA GO:0043065 positive regulation of apoptosis IGI GO:0043410 positive regulation of MAPKKK cascade IEA GO:0044419 interspecies interaction between organisms IEA GO:0045214 sarcomere organization IEA GO:0045665 negative regulation of neuron differentiation IEA GO:0045666 positive regulation of neuron differentiation IEA GO:0045807 positive regulation of endocytosis IEA GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation IEA GO:0050776 regulation of immune response TAS GO:0050900 leukocyte migration TAS GO:0051726 regulation of cell cycle IEA GO:0055007 cardiac muscle cell differentiation IEA GO:0060135 maternal process involved in female pregnancy IEA GO:0070830 tight junction assembly IEA GO:0071260 cellular response to mechanical stimulus IEA GO:0071305 cellular response to vitamin D IEA GO:0071479 cellular response to ionizing radiation IEA GO:0071559 response to transforming growth factor beta stimulus IEA cellular_component GO:0001669 acrosomal vesicle IEA GO:0001726 ruffle TAS GO:0005604 basement membrane IEA GO:0005886 plasma membrane IDA GO:0005886 plasma membrane TAS GO:0005911 cell-cell junction IEA GO:0005912 adherens junction IEA GO:0005925 focal adhesion IDA GO:0005925 focal adhesion IEA GO:0008305 integrin complex IEA GO:0008305 integrin complex NAS GO:0009986 cell surface IDA GO:0009986 cell surface IEA GO:0014704 intercalated disc IEA GO:0016020 membrane IEA GO:0016021 integral to membrane IEA GO:0019717 synaptosome IEA GO:0030056 hemidesmosome IEA GO:0031594 neuromuscular junction IDA GO:0031594 neuromuscular junction IEA GO:0032154 cleavage furrow IEA GO:0032587 ruffle membrane IDA GO:0034667 alpha3-beta1 integrin complex IEA GO:0034679 alpha9-beta1 integrin complex IEA GO:0042383 sarcolemma IDA GO:0042383 sarcolemma IEA GO:0042470 melanosome IEA GO:0043209 myelin sheath IEA GO:0045121 membrane raft IEA molecular_function GO:0001948 glycoprotein binding IEA GO:0001968 fibronectin binding IEA GO:0002020 protease binding IEA GO:0003779 actin binding IEA GO:0004872 receptor activity IEA GO:0005178 integrin binding IEA GO:0005488 binding IEA GO:0005515 protein binding IPI GO:0005518 collagen binding IEA GO:0019901 protein kinase binding IEA GO:0019904 protein domain specific binding IEA GO:0042277 peptide binding IEA GO:0043236 laminin binding IEA GO:0046982 protein heterodimerization activity NAS GO:0051393 alpha-actinin binding IEA

Protein-protein interaction details for ITGB1 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID FLNA Two-hybrid physical 11807098 ITGA3 Reconstituted Complex physical 15254262 RAB8B Affinity Capture-Western physical 12639940 COL1A1 Co-purification physical 2156854 ITGB1BP1 Reconstituted Complex physical 9281591 ITGB1BP1 Affinity Capture-Western physical 9281591 CD9 Affinity Capture-Western physical 8630057 ILK Affinity Capture-Western physical 8538749 ITGA8 Affinity Capture-Western physical 7768999 CD46 Affinity Capture-Western physical 10741407 CD46 Affinity Capture-Western physical 10741407 ITGB1BP1 Reconstituted Complex physical 11741908 FLNB Two-hybrid physical 11807098 FLNB Reconstituted Complex physical 11807098 FLNA Reconstituted Complex physical 11807098 GNB2L1 Affinity Capture-Western physical 9442085 MAP4K4 Two-hybrid physical 11967148 MAP4K4 Reconstituted Complex physical 11967148 MAP4K4 Affinity Capture-Western physical 11967148 ACTN1 Reconstituted Complex physical 2116421 TSPAN4 Affinity Capture-Western physical 9360996 TSPAN4 Affinity Capture-Western physical 9360996 FLNA Two-hybrid physical 9722563 FLNA Reconstituted Complex physical 9722563 FLNA Affinity Capture-Western physical 9722563 CD81 Affinity Capture-Western physical 10229664 FLT4 Affinity Capture-Western physical 11553610 CD9 Affinity Capture-Western physical 12175627 CD63 Affinity Capture-Western physical 12175627 CD81 Affinity Capture-Western physical 12175627 CD151 Affinity Capture-Western physical 12175627 CANX Affinity Capture-Western physical 8163531 ITGA9 Affinity Capture-Western physical 8245132 FBXO2 Affinity Capture-Western physical 12140560 CD47 Affinity Capture-Western physical 10397731 TLN1 Protein-peptide physical 11279249 PRKCA Affinity Capture-Western physical 12435334 GNB2L1 Affinity Capture-Western physical 12435334 ITGA6 Affinity Capture-Western physical 9660880 YWHAB Affinity Capture-Western physical 11313964 YWHAB Two-hybrid physical 11313964 YWHAB Reconstituted Complex physical 11313964 NME1 Affinity Capture-Western physical 11919189 NME1 Two-hybrid physical 11919189 PRKCA Affinity Capture-Western physical 12138200 PXN Affinity Capture-Western physical 10804218 FHL2 Two-hybrid physical 10906324 FHL2 Affinity Capture-Western physical 10906324 CD36 Affinity Capture-Western physical 11238109 LGALS8 Affinity Capture-Western physical 10852818 LGALS8 Reconstituted Complex physical 10852818 ITGA10 Affinity Capture-Western physical 9685391 SLC3A2 Affinity Capture-Western physical 12181350 LAMA1 Reconstituted Complex physical 9688542 TGOLN2 Affinity Capture-Western physical 11208159 VCP Affinity Capture-Western physical 15723043 ITGA3 Affinity Capture-Western physical 16878156 ITGA5 Affinity Capture-Western physical 20643357 ITGA5 Affinity Capture-Western physical 20643357 UBC Affinity Capture-MS physical 21987572