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Gene
Protein
Transcript
Promoter
Expression
GO/PPI
PubMed
Cross reference
Gene Ontology information for LDLR (
Homo sapiens
)
(Information is obtained from AmiGO)
ID
Term
Evidence
biological_process
GO:0006629
lipid metabolic process
TAS
GO:0006810
transport
IEA
GO:0006869
lipid transport
IEA
GO:0006897
endocytosis
TAS
GO:0006898
receptor-mediated endocytosis
TAS
GO:0007568
aging
IEA
GO:0008202
steroid metabolic process
IEA
GO:0008203
cholesterol metabolic process
IEA
GO:0009725
response to hormone stimulus
IEA
GO:0030299
intestinal cholesterol absorption
IMP
GO:0030301
cholesterol transport
IMP
GO:0032355
response to estradiol stimulus
IEA
GO:0033762
response to glucagon stimulus
IEA
GO:0034383
low-density lipoprotein particle clearance
IMP
GO:0042157
lipoprotein metabolic process
TAS
GO:0042159
lipoprotein catabolic process
IEA
GO:0042632
cholesterol homeostasis
IMP
GO:0044419
interspecies interaction between organisms
IEA
cellular_component
GO:0005764
lysosome
IDA
GO:0005769
early endosome
IDA
GO:0005886
plasma membrane
TAS
GO:0005887
integral to plasma membrane
TAS
GO:0005901
caveola
IEA
GO:0005905
coated pit
IDA
GO:0009897
external side of plasma membrane
IDA
GO:0010008
endosome membrane
TAS
GO:0016020
membrane
IEA
GO:0016021
integral to membrane
IEA
GO:0030669
clathrin-coated endocytic vesicle membrane
TAS
GO:0034362
low-density lipoprotein particle
IEA
GO:0055038
recycling endosome membrane
IEA
molecular_function
GO:0004872
receptor activity
IEA
GO:0005041
low-density lipoprotein receptor activity
IDA
GO:0005509
calcium ion binding
IEA
GO:0005515
protein binding
IPI
GO:0030229
very-low-density lipoprotein particle receptor activity
IDA
Protein-protein interaction details for LDLR (
Homo sapiens
)
(Information is obtained from BioGRID)
Interacting human protein
Experiment
Type
PubMed ID
DAB1
Two-hybrid
physical
10827173
PF4
Reconstituted Complex
physical
11986215
CD36
Reconstituted Complex
physical
9555943
DAB2
Reconstituted Complex
physical
11247302
AP1M2
Affinity Capture-Western
physical
11157985
LDLRAP1
Reconstituted Complex
physical
12221107
LRPAP1
Reconstituted Complex
physical
7822276
SNX17
Reconstituted Complex
physical
12169628
SNX17
Affinity Capture-Western
physical
12169628
DAB1
Reconstituted Complex
physical
9837937
HSPA5
Affinity Capture-MS
physical
10906332
UBC
Affinity Capture-Western
physical
19520913
MYLIP
Biochemical Activity
physical
21734303
MYLIP
Affinity Capture-Western
physical
21734303
UBC
Affinity Capture-Western
physical
22074827
UBC
Reconstituted Complex
physical
21685362
MYLIP
Biochemical Activity
physical
21685362