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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for LDLR (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0006629lipid metabolic processTAS
GO:0006810transportIEA
GO:0006869lipid transportIEA
GO:0006897endocytosisTAS
GO:0006898receptor-mediated endocytosisTAS
GO:0007568agingIEA
GO:0008202steroid metabolic processIEA
GO:0008203cholesterol metabolic processIEA
GO:0009725response to hormone stimulusIEA
GO:0030299intestinal cholesterol absorptionIMP
GO:0030301cholesterol transportIMP
GO:0032355response to estradiol stimulusIEA
GO:0033762response to glucagon stimulusIEA
GO:0034383low-density lipoprotein particle clearanceIMP
GO:0042157lipoprotein metabolic processTAS
GO:0042159lipoprotein catabolic processIEA
GO:0042632cholesterol homeostasisIMP
GO:0044419interspecies interaction between organismsIEA
cellular_component
GO:0005764lysosomeIDA
GO:0005769early endosomeIDA
GO:0005886plasma membraneTAS
GO:0005887integral to plasma membraneTAS
GO:0005901caveolaIEA
GO:0005905coated pitIDA
GO:0009897external side of plasma membraneIDA
GO:0010008endosome membraneTAS
GO:0016020membraneIEA
GO:0016021integral to membraneIEA
GO:0030669clathrin-coated endocytic vesicle membraneTAS
GO:0034362low-density lipoprotein particleIEA
GO:0055038recycling endosome membraneIEA
molecular_function
GO:0004872receptor activityIEA
GO:0005041low-density lipoprotein receptor activityIDA
GO:0005509calcium ion bindingIEA
GO:0005515protein bindingIPI
GO:0030229very-low-density lipoprotein particle receptor activityIDA

Protein-protein interaction details for LDLR (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
DAB1Two-hybridphysical10827173
PF4Reconstituted Complexphysical11986215
CD36Reconstituted Complexphysical9555943
DAB2Reconstituted Complexphysical11247302
AP1M2Affinity Capture-Westernphysical11157985
LDLRAP1Reconstituted Complexphysical12221107
LRPAP1Reconstituted Complexphysical7822276
SNX17Reconstituted Complexphysical12169628
SNX17Affinity Capture-Westernphysical12169628
DAB1Reconstituted Complexphysical9837937
HSPA5Affinity Capture-MSphysical10906332
UBCAffinity Capture-Westernphysical19520913
MYLIPBiochemical Activityphysical21734303
MYLIPAffinity Capture-Westernphysical21734303
UBCAffinity Capture-Westernphysical22074827
UBCReconstituted Complexphysical21685362
MYLIPBiochemical Activityphysical21685362