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Gene
Protein
Transcript
Promoter
Expression
GO/PPI
PubMed
Cross reference
Gene Ontology information for LIFR (
Homo sapiens
)
(Information is obtained from AmiGO)
ID
Term
Evidence
biological_process
GO:0007166
cell surface receptor linked signaling pathway
TAS
GO:0008284
positive regulation of cell proliferation
IDA
GO:0008284
positive regulation of cell proliferation
IEA
GO:0019221
cytokine-mediated signaling pathway
IDA
GO:0031100
organ regeneration
IEA
GO:0034097
response to cytokine stimulus
IDA
GO:0042221
response to chemical stimulus
IEA
GO:0045768
positive regulation of anti-apoptosis
IEA
GO:0048812
neuron projection morphogenesis
IEA
GO:0048861
leukemia inhibitory factor signaling pathway
IDA
GO:0048861
leukemia inhibitory factor signaling pathway
TAS
GO:0070120
ciliary neurotrophic factor-mediated signaling pathway
IDA
cellular_component
GO:0005576
extracellular region
IEA
GO:0005886
plasma membrane
IEA
GO:0005887
integral to plasma membrane
TAS
molecular_function
GO:0004872
receptor activity
IEA
GO:0004897
ciliary neurotrophic factor receptor activity
IDA
GO:0004923
leukemia inhibitory factor receptor activity
IDA
GO:0004923
leukemia inhibitory factor receptor activity
IEA
GO:0004924
oncostatin-M receptor activity
IDA
GO:0005127
ciliary neurotrophic factor receptor binding
IPI
GO:0019838
growth factor binding
IPI
GO:0019955
cytokine binding
IEA
Protein-protein interaction details for LIFR (
Homo sapiens
)
(Information is obtained from BioGRID)
Interacting human protein
Experiment
Type
PubMed ID
CNTFR
Reconstituted Complex
physical
12707266
CNTFR
Affinity Capture-Western
physical
12707266
LIF
Reconstituted Complex
physical
12601009
OSM
Affinity Capture-Western
physical
1536831
IL6ST
Affinity Capture-Western
physical
12047380
IL6ST
Affinity Capture-Western
physical
8999038
CNTFR
Reconstituted Complex
physical
11943154
PTPN6
Affinity Capture-Western
physical
10800945
UBC
Affinity Capture-MS
physical
20639865