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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for LIFR (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0007166cell surface receptor linked signaling pathwayTAS
GO:0008284positive regulation of cell proliferationIDA
GO:0008284positive regulation of cell proliferationIEA
GO:0019221cytokine-mediated signaling pathwayIDA
GO:0031100organ regenerationIEA
GO:0034097response to cytokine stimulusIDA
GO:0042221response to chemical stimulusIEA
GO:0045768positive regulation of anti-apoptosisIEA
GO:0048812neuron projection morphogenesisIEA
GO:0048861leukemia inhibitory factor signaling pathwayIDA
GO:0048861leukemia inhibitory factor signaling pathwayTAS
GO:0070120ciliary neurotrophic factor-mediated signaling pathwayIDA
cellular_component
GO:0005576extracellular regionIEA
GO:0005886plasma membraneIEA
GO:0005887integral to plasma membraneTAS
molecular_function
GO:0004872receptor activityIEA
GO:0004897ciliary neurotrophic factor receptor activityIDA
GO:0004923leukemia inhibitory factor receptor activityIDA
GO:0004923leukemia inhibitory factor receptor activityIEA
GO:0004924oncostatin-M receptor activityIDA
GO:0005127ciliary neurotrophic factor receptor bindingIPI
GO:0019838growth factor bindingIPI
GO:0019955cytokine bindingIEA

Protein-protein interaction details for LIFR (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
CNTFRReconstituted Complexphysical12707266
CNTFRAffinity Capture-Westernphysical12707266
LIFReconstituted Complexphysical12601009
OSMAffinity Capture-Westernphysical1536831
IL6STAffinity Capture-Westernphysical12047380
IL6STAffinity Capture-Westernphysical8999038
CNTFRReconstituted Complexphysical11943154
PTPN6Affinity Capture-Westernphysical10800945
UBCAffinity Capture-MSphysical20639865