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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for LMNA (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0006915 apoptosis TAS GO:0006921 cellular component disassembly involved in apoptosis TAS GO:0006998 nuclear envelope organization IEA GO:0007283 spermatogenesis IEA GO:0007517 muscle organ development IMP GO:0030334 regulation of cell migration ISS GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity ISS GO:0034504 protein localization to nucleus ISS GO:0035105 sterol regulatory element binding protein import into nucleus IEA GO:0042981 regulation of apoptosis ISS GO:0055015 ventricular cardiac muscle cell development IEA GO:0071456 cellular response to hypoxia IEP GO:0090343 positive regulation of cell aging IDA cellular_component GO:0005626 insoluble fraction IEA GO:0005634 nucleus IDA GO:0005635 nuclear envelope IDA GO:0005635 nuclear envelope TAS GO:0005638 lamin filament IEA GO:0005638 lamin filament TAS GO:0005652 nuclear lamina TAS GO:0005654 nucleoplasm TAS GO:0005737 cytoplasm IDA GO:0005882 intermediate filament IEA GO:0005882 intermediate filament TAS GO:0016363 nuclear matrix IEA GO:0048471 perinuclear region of cytoplasm IDA molecular_function GO:0005198 structural molecule activity IEA GO:0005198 structural molecule activity TAS GO:0005515 protein binding IPI

Protein-protein interaction details for LMNA (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID LMNB1 Two-hybrid physical 11792809 SREBF1 Two-hybrid physical 11929849 NARF Two-hybrid physical 10514485 EMD Two-hybrid physical 12755701 EMD Affinity Capture-Western physical 12755701 EMD Affinity Capture-Western physical 12670476 KAT5 Two-hybrid physical 16169070 TMPO Affinity Capture-Western physical 12475961 ZNF239 Two-hybrid physical 12409453 ZNF239 Reconstituted Complex physical 12409453 SYNE1 Affinity Capture-Western physical 11801724 RB1 Reconstituted Complex physical 8278403 ALOX12 Two-hybrid physical 10727209 ALOX12 Affinity Capture-Western physical 10727209 TMPO Co-localization physical 10984438 TMPO Affinity Capture-Western physical 10984438 TMPO Far Western physical 10984438 TMPO Far Western physical 10984438 SYNE1 Reconstituted Complex physical 12163176 NARF Reconstituted Complex physical 10514485 PRKCA Protein-peptide physical 12112001 TOR1A Reconstituted Complex physical 8324822 TOR1AIP1 Reconstituted Complex physical 8324822 EMD Affinity Capture-Western physical 11173535 EMD Two-hybrid physical 11173535 EMD Reconstituted Complex physical 10673356 SREBF1 Reconstituted Complex physical 11929849 SREBF1 Affinity Capture-Western physical 11929849 FYCO1 Affinity Capture-MS physical 20562859 BANF1 Affinity Capture-MS physical 19759913 RBBP4 Two-hybrid physical 19734887 RBBP4 Reconstituted Complex physical 19734887 ING1 Affinity Capture-Western physical 18836436 ING1 Affinity Capture-Western physical 18836436 CTNNB1 Affinity Capture-Western physical 15355978 SRRM1 Affinity Capture-MS physical 16159877 SRRM2 Affinity Capture-MS physical 16159877 EMD Affinity Capture-MS physical 17620012 MORF4L1 Affinity Capture-MS physical 17573780 MORF4L2 Affinity Capture-MS physical 17573780 C20orf20 Affinity Capture-MS physical 17573780 H2AFX Affinity Capture-MS physical 20000738 MYC Affinity Capture-MS physical 17314511 UCHL5 Reconstituted Complex physical 21800051 YWHAQ Affinity Capture-MS physical 20618440 MME Affinity Capture-MS physical 17342744 YWHAQ Affinity Capture-MS physical 15161933 CTCF Affinity Capture-MS physical 14759373 UBC Reconstituted Complex physical 19850743 SUMO1 Affinity Capture-MS physical 19596686 SUMO1 Reconstituted Complex physical 19596686 SVIL Two-hybrid physical 20309963 UBC Affinity Capture-MS physical 22178446 UBC Affinity Capture-MS physical 21987572