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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for LPL (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0006629lipid metabolic processIEA
GO:0006629lipid metabolic processTAS
GO:0006633fatty acid biosynthetic processIC
GO:0006633fatty acid biosynthetic processIDA
GO:0006633fatty acid biosynthetic processISS
GO:0006641triglyceride metabolic processISS
GO:0006644phospholipid metabolic processISS
GO:0010744positive regulation of macrophage derived foam cell differentiationIC
GO:0010744positive regulation of macrophage derived foam cell differentiationIEA
GO:0010886positive regulation of cholesterol storageIMP
GO:0010890positive regulation of sequestering of triglycerideIMP
GO:0016042lipid catabolic processIEA
GO:0019432triglyceride biosynthetic processIEA
GO:0019433triglyceride catabolic processIDA
GO:0019433triglyceride catabolic processISS
GO:0034371chylomicron remodelingIC
GO:0034372very-low-density lipoprotein particle remodelingIDA
GO:0034372very-low-density lipoprotein particle remodelingISS
GO:0042157lipoprotein metabolic processTAS
GO:0042493response to drugIEA
GO:0070328triglyceride homeostasisIGI
cellular_component
GO:0005576extracellular regionTAS
GO:0005615extracellular spaceIDA
GO:0005886plasma membraneIEA
GO:0031012extracellular matrixIEA
GO:0031225anchored to membraneIEA
GO:0034361very-low-density lipoprotein particleIEA
GO:0042627chylomicronIEA
molecular_function
GO:0004465lipoprotein lipase activityIDA
GO:0004465lipoprotein lipase activityIEA
GO:0004465lipoprotein lipase activityISS
GO:0004465lipoprotein lipase activityTAS
GO:0004620phospholipase activityISS
GO:0004806triglyceride lipase activityIDA
GO:0004806triglyceride lipase activityISS
GO:0005102receptor bindingIPI
GO:0005515protein bindingIPI
GO:0008201heparin bindingIDA
GO:0016787hydrolase activityIEA
GO:0017129triglyceride bindingIEA

Protein-protein interaction details for LPL (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
EMDTwo-hybridphysical12755701
ASCC2Two-hybridphysical16169070
UBE2ZTwo-hybridphysical16169070
RPL18ATwo-hybridphysical16169070
COPS6Two-hybridphysical16169070
KIAA1377Two-hybridphysical16169070
LUC7L2Two-hybridphysical16169070
PTPN4Two-hybridphysical16169070
LRP2Reconstituted Complexphysical7686151
VLDLRReconstituted Complexphysical7592875
LRP1Reconstituted Complexphysical7510694
LRP1Reconstituted Complexphysical7989348
LRP1Reconstituted Complexphysical1281473
PLK1Affinity Capture-MSphysical19596235