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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for MEF2C (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000002 mitochondrial genome maintenance IEA GO:0000122 negative regulation of transcription from RNA polymerase II promoter IMP GO:0000165 MAPKKK cascade IDA GO:0000165 MAPKKK cascade IMP GO:0001568 blood vessel development IEA GO:0001568 blood vessel development ISS GO:0001649 osteoblast differentiation IEA GO:0001649 osteoblast differentiation ISS GO:0001782 B cell homeostasis ISS GO:0001947 heart looping ISS GO:0001958 endochondral ossification IEA GO:0001958 endochondral ossification ISS GO:0001974 blood vessel remodeling IEA GO:0001974 blood vessel remodeling ISS GO:0002062 chondrocyte differentiation IEA GO:0002062 chondrocyte differentiation ISS GO:0002224 toll-like receptor signaling pathway TAS GO:0002467 germinal center formation ISS GO:0002634 regulation of germinal center formation IEA GO:0002634 regulation of germinal center formation ISS GO:0002755 MyD88-dependent toll-like receptor signaling pathway TAS GO:0002756 MyD88-independent toll-like receptor signaling pathway TAS GO:0003138 primary heart field specification ISS GO:0003139 secondary heart field specification ISS GO:0003151 outflow tract morphogenesis IEA GO:0003151 outflow tract morphogenesis ISS GO:0003185 sinoatrial valve morphogenesis ISS GO:0003211 cardiac ventricle formation IEA GO:0003211 cardiac ventricle formation ISS GO:0006351 transcription, DNA-dependent IDA GO:0006366 transcription from RNA polymerase II promoter ISS GO:0006915 apoptosis IEA GO:0006959 humoral immune response ISS GO:0007275 multicellular organismal development IEA GO:0007399 nervous system development IEA GO:0007507 heart development IEP GO:0007507 heart development ISS GO:0007507 heart development NAS GO:0007517 muscle organ development TAS GO:0007519 skeletal muscle tissue development IEA GO:0007519 skeletal muscle tissue development ISS GO:0007521 muscle cell fate determination IEA GO:0007521 muscle cell fate determination ISS GO:0007611 learning or memory IEA GO:0007611 learning or memory ISS GO:0008063 Toll signaling pathway TAS GO:0009615 response to virus IEP GO:0010628 positive regulation of gene expression IDA GO:0010629 negative regulation of gene expression ISS GO:0010694 positive regulation of alkaline phosphatase activity ISS GO:0014033 neural crest cell differentiation ISS GO:0014902 myotube differentiation IEP GO:0030182 neuron differentiation IEP GO:0030182 neuron differentiation ISS GO:0030220 platelet formation ISS GO:0030279 negative regulation of ossification IDA GO:0030318 melanocyte differentiation ISS GO:0030501 positive regulation of bone mineralization ISS GO:0030890 positive regulation of B cell proliferation ISS GO:0034130 toll-like receptor 1 signaling pathway TAS GO:0034134 toll-like receptor 2 signaling pathway TAS GO:0034138 toll-like receptor 3 signaling pathway TAS GO:0034142 toll-like receptor 4 signaling pathway TAS GO:0035051 cardiac cell differentiation IEA GO:0035690 cellular response to drug ISS GO:0035984 cellular response to trichostatin A ISS GO:0042100 B cell proliferation IEA GO:0042100 B cell proliferation ISS GO:0042692 muscle cell differentiation TAS GO:0043524 negative regulation of neuron apoptosis ISS GO:0045087 innate immune response TAS GO:0045652 regulation of megakaryocyte differentiation IEA GO:0045652 regulation of megakaryocyte differentiation ISS GO:0045663 positive regulation of myoblast differentiation IMP GO:0045666 positive regulation of neuron differentiation ISS GO:0045669 positive regulation of osteoblast differentiation ISS GO:0045885 positive regulation of survival gene product expression IMP GO:0045893 positive regulation of transcription, DNA-dependent IDA GO:0045944 positive regulation of transcription from RNA polymerase II promoter IDA GO:0045944 positive regulation of transcription from RNA polymerase II promoter IEA GO:0045944 positive regulation of transcription from RNA polymerase II promoter IMP GO:0048011 nerve growth factor receptor signaling pathway TAS GO:0048311 mitochondrion distribution IEA GO:0048643 positive regulation of skeletal muscle tissue development IMP GO:0048666 neuron development IEA GO:0048666 neuron development ISS GO:0050853 B cell receptor signaling pathway ISS GO:0051145 smooth muscle cell differentiation IEA GO:0051145 smooth muscle cell differentiation ISS GO:0051149 positive regulation of muscle cell differentiation TAS GO:0051403 stress-activated MAPK cascade TAS GO:0055005 ventricular cardiac myofibril development IEA GO:0055012 ventricular cardiac muscle cell differentiation ISS GO:0060025 regulation of synaptic activity IEA GO:0060025 regulation of synaptic activity ISS GO:0060045 positive regulation of cardiac muscle cell proliferation ISS GO:0061333 renal tubule morphogenesis ISS GO:0061337 cardiac conduction IEA GO:0071222 cellular response to lipopolysaccharide ISS GO:0071277 cellular response to calcium ion ISS GO:0071374 cellular response to parathyroid hormone stimulus IDA GO:0071498 cellular response to fluid shear stress ISS GO:0071560 cellular response to transforming growth factor beta stimulus IDA GO:0072102 glomerulus morphogenesis ISS GO:0072160 nephron tubule epithelial cell differentiation ISS GO:0090073 positive regulation of protein homodimerization activity IEA GO:0090073 positive regulation of protein homodimerization activity ISS GO:2000111 positive regulation of macrophage apoptosis ISS GO:2000727 positive regulation of cardiac muscle cell differentiation IDA GO:2000987 positive regulation of behavioral fear response ISS GO:2001013 epithelial cell proliferation involve in renal tubule morphogenesis ISS GO:2001016 positive regulation of skeletal muscle cell differentiation IDA cellular_component GO:0000790 nuclear chromatin IEA GO:0005634 nucleus IDA GO:0005634 nucleus IEA GO:0005654 nucleoplasm TAS GO:0005730 nucleolus IDA GO:0005737 cytoplasm IDA GO:0016607 nuclear speck IDA GO:0043231 intracellular membrane-bounded organelle IDA GO:0043234 protein complex IDA molecular_function GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IDA GO:0000981 sequence-specific DNA binding RNA polymerase II transcription factor activity ISS GO:0000983 RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity IDA GO:0001077 RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription IDA GO:0003677 DNA binding IDA GO:0003680 AT DNA binding IDA GO:0003700 sequence-specific DNA binding transcription factor activity IDA GO:0003700 sequence-specific DNA binding transcription factor activity IEA GO:0005515 protein binding IPI GO:0019901 protein kinase binding IEA GO:0033613 activating transcription factor binding IEA GO:0033613 activating transcription factor binding IPI GO:0035198 miRNA binding IDA GO:0042826 histone deacetylase binding IEA GO:0043565 sequence-specific DNA binding IEA GO:0044212 transcription regulatory region DNA binding IEA GO:0044212 transcription regulatory region DNA binding ISS GO:0046982 protein heterodimerization activity IPI

Protein-protein interaction details for MEF2C (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID HDAC4 Affinity Capture-Western physical 10523670 HDAC4 Reconstituted Complex physical 10523670 HDAC4 Reconstituted Complex physical 11486037 EP300 Phenotypic Enhancement genetic 9001254 EP300 Reconstituted Complex physical 9001254 SP1 Two-hybrid physical 9748305 SP1 Affinity Capture-Western physical 9748305 SOX18 Reconstituted Complex physical 11554755 SOX18 Affinity Capture-Western physical 11554755 SMAD2 Reconstituted Complex physical 11160896 TEAD1 Reconstituted Complex physical 12061776 TEAD1 Affinity Capture-Western physical 12061776 TWIST2 Affinity Capture-Western physical 11809751 MYOD1 Two-hybrid physical 9418854 MYOG Reconstituted Complex physical 8548800 MAPK7 Reconstituted Complex physical 9753748 MAPK7 Biochemical Activity physical 9753748 EPAS1 Two-hybrid physical 20936779 MAPK14 Two-hybrid physical 20936779 MAPK7 Two-hybrid physical 20936779 SPTBN1 Two-hybrid physical 20936779 YWHAZ Two-hybrid physical 20936779 HDAC9 Two-hybrid physical 20936779 COPS5 Two-hybrid physical 20936779 SIRT1 Co-localization physical 19553684 HDAC9 Two-hybrid physical 20211142 HDAC4 Reconstituted Complex physical 12709441 HDAC7 Affinity Capture-Western physical 18463162 NCOA2 Reconstituted Complex physical 12130539 NCOA2 Reconstituted Complex physical 12130539 HDAC4 Two-hybrid physical 15964851 IFRD1 Reconstituted Complex physical 15743821 MYOD1 Reconstituted Complex physical 15743821 IFRD1 Reconstituted Complex physical 15743821 HDAC4 Affinity Capture-Western physical 15743821 IFRD1 Affinity Capture-Western physical 15743821 HDAC4 Affinity Capture-Western physical 18332106 HDAC4 Reconstituted Complex physical 11279209 HDAC5 Reconstituted Complex physical 11279209 HDAC7 Reconstituted Complex physical 11279209 HDAC7 Reconstituted Complex physical 11279209