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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for MGMT (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0006266 DNA ligation TAS GO:0006281 DNA repair TAS GO:0006306 DNA methylation TAS GO:0006307 DNA dealkylation involved in DNA repair IEA GO:0009636 response to toxin IEA GO:0032259 methylation TAS GO:0034599 cellular response to oxidative stress IEA GO:0042493 response to drug IEA GO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process IEA GO:0045471 response to ethanol IEA GO:0045739 positive regulation of DNA repair IEA GO:0051593 response to folic acid IEA GO:0060548 negative regulation of cell death IEA GO:0060644 mammary gland epithelial cell differentiation IEA GO:0071407 cellular response to organic cyclic compound IEA GO:0071479 cellular response to ionizing radiation IEA cellular_component GO:0005634 nucleus IEA GO:0005654 nucleoplasm TAS molecular_function GO:0003677 DNA binding IEA GO:0003908 methylated-DNA-[protein]-cysteine S-methyltransferase activity IEA GO:0005509 calcium ion binding IEA GO:0008168 methyltransferase activity TAS GO:0009008 DNA-methyltransferase activity TAS GO:0016740 transferase activity IEA

Protein-protein interaction details for MGMT (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID CSNK2A1 Biochemical Activity physical 10667577 CSNK2A2 Biochemical Activity physical 10667577 PRKACA Biochemical Activity physical 10667577 PRKCA Biochemical Activity physical 10667577 ESR1 Affinity Capture-Western physical 11564893 CREBBP Affinity Capture-Western physical 11564893 EP300 Affinity Capture-Western physical 11564893 ESR1 Reconstituted Complex physical 11564893 ESR1 Two-hybrid physical 11564893 SMC1A Affinity Capture-MS physical 16226712 HIST1H4A Affinity Capture-MS physical 16226712 HIST1H2AM Affinity Capture-MS physical 16226712 H2BFM Affinity Capture-MS physical 16226712 HIST3H3 Affinity Capture-MS physical 16226712 MCM3 Affinity Capture-MS physical 16226712 MSH2 Affinity Capture-MS physical 16226712 TOP1 Affinity Capture-MS physical 16226712 PRKDC Affinity Capture-MS physical 16226712 XRCC6 Affinity Capture-MS physical 16226712 DDX5 Affinity Capture-MS physical 16226712 DDX24 Affinity Capture-MS physical 16226712 USP19 Affinity Capture-MS physical 16226712 RNF8 Affinity Capture-MS physical 16226712 PSME2 Affinity Capture-MS physical 16226712 UBB Affinity Capture-MS physical 16226712 PSMD9 Affinity Capture-MS physical 16226712 FBXO2 Affinity Capture-MS physical 16226712 FBXO27 Affinity Capture-MS physical 16226712 HSP90AA1 Affinity Capture-MS physical 16226712 HSP90AB1 Affinity Capture-MS physical 16226712 CDK12 Affinity Capture-MS physical 16226712 CDK10 Affinity Capture-MS physical 16226712 PRKCH Affinity Capture-MS physical 16226712 PRPF4 Affinity Capture-MS physical 16226712 CDKL5 Affinity Capture-MS physical 16226712 SET Affinity Capture-MS physical 16226712 PTPN4 Affinity Capture-MS physical 16226712 YWHAZ Affinity Capture-MS physical 16226712 KPNB1 Affinity Capture-MS physical 16226712 WNT9B Affinity Capture-MS physical 16226712 PABPC3 Affinity Capture-MS physical 16226712 ANP32E Affinity Capture-MS physical 16226712 NCL Affinity Capture-MS physical 16226712 HNRNPA2B1 Affinity Capture-MS physical 16226712 HNRNPC Affinity Capture-MS physical 16226712 RPS15A Affinity Capture-MS physical 16226712 RPLP1 Affinity Capture-MS physical 16226712 EIF3H Affinity Capture-MS physical 16226712 EEF1A1 Affinity Capture-MS physical 16226712 EEF1A2 Affinity Capture-MS physical 16226712 EEF1B2 Affinity Capture-MS physical 16226712 SLC25A4 Affinity Capture-MS physical 16226712 SLC25A6 Affinity Capture-MS physical 16226712 PKM2 Affinity Capture-MS physical 16226712 TTPA Affinity Capture-MS physical 16226712 IL25 Affinity Capture-MS physical 16226712 FBL Affinity Capture-MS physical 16226712 TUBB2C Affinity Capture-MS physical 16226712 TUBA1C Affinity Capture-MS physical 16226712 ANXA1 Affinity Capture-MS physical 16226712 ANXA2 Affinity Capture-MS physical 16226712 ACTB Affinity Capture-MS physical 16226712 MYO7A Affinity Capture-MS physical 16226712 VIM Affinity Capture-MS physical 16226712 PHB Affinity Capture-MS physical 16226712 SRP9 Affinity Capture-MS physical 16226712 SSRP1 Affinity Capture-MS physical 16226712 PCNA Affinity Capture-Western physical 16226712 CDK2 Affinity Capture-Western physical 16226712 CDK1 Affinity Capture-Western physical 16226712 CCNB1 Affinity Capture-Western physical 16226712 CDKN1A Affinity Capture-Western physical 16226712 MCM2 Affinity Capture-Western physical 16226712 ORC1L Affinity Capture-Western physical 16226712 POLD1 Affinity Capture-Western physical 16226712 HSP90AA1 Affinity Capture-Western physical 16226712 UBC Reconstituted Complex physical 12016156 BRCA2 Affinity Capture-Western physical 19047179