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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for NCK1 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0006417 regulation of translation IEA GO:0007015 actin filament organization IEA GO:0007172 signal complex assembly NAS GO:0007411 axon guidance TAS GO:0016477 cell migration IEA GO:0030032 lamellipodium assembly IEA GO:0030838 positive regulation of actin filament polymerization IMP GO:0042102 positive regulation of T cell proliferation IMP GO:0042110 T cell activation IMP GO:0050852 T cell receptor signaling pathway TAS cellular_component GO:0005634 nucleus IEA GO:0005737 cytoplasm NAS GO:0005783 endoplasmic reticulum IEA GO:0005829 cytosol TAS GO:0012506 vesicle membrane IEA molecular_function GO:0005102 receptor binding IPI GO:0005515 protein binding IPI GO:0008093 cytoskeletal adaptor activity NAS GO:0019904 protein domain specific binding IEA GO:0030159 receptor signaling complex scaffold activity NAS

Protein-protein interaction details for NCK1 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID EPHB1 Two-hybrid physical 9430661 MINK1 Two-hybrid physical 15469942 ERBB4 Affinity Capture-MS physical 16729043 MINK1 Reconstituted Complex physical 15469942 LCP2 Affinity Capture-Western physical 15388330 ARHGAP32 Reconstituted Complex physical 12819203 ARHGAP32 Affinity Capture-Western physical 12819203 BLNK Affinity Capture-Western physical 9697839 SOS1 Affinity Capture-Western physical 10206341 DNM1 Reconstituted Complex physical 10206341 DNM1 Affinity Capture-Western physical 10206341 SOCS1 Reconstituted Complex physical 10022833 RASA1 Affinity Capture-Western physical 9233798 PKN2 Reconstituted Complex physical 8910519 WASL Far Western physical 11340081 WASL Reconstituted Complex physical 11340081 RRAS Reconstituted Complex physical 10671570 RRAS Affinity Capture-Western physical 10671570 RRAS Two-hybrid physical 10671570 EGFR Reconstituted Complex physical 9362449 KHDRBS1 Reconstituted Complex physical 9362449 MAP4K4 Reconstituted Complex physical 9135144 MAP4K4 Affinity Capture-Western physical 9135144 DAG1 Reconstituted Complex physical 11724572 DAG1 Affinity Capture-Western physical 11724572 PXN Reconstituted Complex physical 10330411 LCP2 Reconstituted Complex physical 10229072 MAP4K1 Two-hybrid physical 9346925 SOS1 Affinity Capture-Western physical 7862111 SOS1 Reconstituted Complex physical 7862111 NEDD9 Affinity Capture-Western physical 8879209 NEDD9 Reconstituted Complex physical 8879209 CRK Reconstituted Complex physical 8879209 PTK2 Reconstituted Complex physical 8879209 DCC Affinity Capture-Western physical 12149262 WAS Affinity Capture-Western physical 10747096 EIF2B2 Affinity Capture-Western physical 11959995 EIF2B2 Reconstituted Complex physical 11959995 EIF2B2 Two-hybrid physical 11959995 EGFR Affinity Capture-Western physical 1333047 PDGFRB Affinity Capture-Western physical 1333047 TBK1 Reconstituted Complex physical 7706279 TBK1 Affinity Capture-Western physical 7706279 SOS1 Reconstituted Complex physical 8810325 SOS1 Affinity Capture-Western physical 8810325 PAK1 Affinity Capture-Western physical 11157752 CBL Affinity Capture-Western physical 10204582 RALGPS1 Affinity Capture-Western physical 10747847 SOCS7 Two-hybrid physical 9344857 SOCS7 Reconstituted Complex physical 9344857 FASLG Reconstituted Complex physical 11741599 DRD4 Reconstituted Complex physical 9843378 MAP4K1 Reconstituted Complex physical 9891069 CD3E Reconstituted Complex physical 12110186 PTK2 Affinity Capture-Western physical 11950595 PTK2 Reconstituted Complex physical 11950595 PKN2 Affinity Capture-Western physical 10026169 PAK1 Affinity Capture-Western physical 10026169 SOS1 Affinity Capture-Western physical 10026169 EGFR Affinity Capture-Western physical 10026169 PDGFRB Affinity Capture-Western physical 10026169 ABL1 Affinity Capture-Western physical 11494134 CBL Affinity Capture-Western physical 11494134 GAB2 Reconstituted Complex physical 10391903 WAS Affinity Capture-Western physical 12135674 BCAR1 Affinity Capture-Western physical 12135674 KHDRBS1 Far Western physical 9010224 KHDRBS1 Affinity Capture-Western physical 9010224 ABI1 Reconstituted Complex physical 11418237 WIPF1 Two-hybrid physical 9694849 WIPF1 Affinity Capture-Western physical 9694849 PFN1 Reconstituted Complex physical 9694849 DOK2 Affinity Capture-Western physical 11689432 CAV2 Reconstituted Complex physical 12091389 PAK1 Reconstituted Complex physical 8824201 PAK1 Affinity Capture-Western physical 8824201 MAP4K1 Affinity Capture-Western physical 11279207 WAS Reconstituted Complex physical 7565724 WAS Affinity Capture-Western physical 7565724 EPHB1 Affinity Capture-Western physical 9430661 NCKIPSD Reconstituted Complex physical 11278500 NCKIPSD Affinity Capture-Western physical 11278500 NCKIPSD Two-hybrid physical 11278500 ABL1 Reconstituted Complex physical 7926767 ABL1 Two-hybrid physical 7926767 RASA1 Affinity Capture-Western physical 21664272 RASA1 Affinity Capture-Western physical 21664272 RASA1 Far Western physical 21664272 RASA1 Far Western physical 21664272 RASA1 Reconstituted Complex physical 21664272 RASA1 Reconstituted Complex physical 21664272 UBA52 Two-hybrid physical 21900206