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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for NFE2L2 (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0006355regulation of transcription, DNA-dependentTAS
GO:0006366transcription from RNA polymerase II promoterTAS
GO:0030194positive regulation of blood coagulationIEA
GO:0030968endoplasmic reticulum unfolded protein responseIEA
GO:0034599cellular response to oxidative stressIEA
GO:0045944positive regulation of transcription from RNA polymerase II promoterIEA
GO:0045995regulation of embryonic developmentIEA
GO:2000121regulation of removal of superoxide radicalsIEA
GO:2000379positive regulation of reactive oxygen species metabolic processIEA
cellular_component
GO:0000785chromatinIEA
GO:0005634nucleusIDA
GO:0005634nucleusIEA
GO:0005737cytoplasmIDA
GO:0005737cytoplasmIEA
GO:0005813centrosomeIDA
GO:0005829cytosolIEA
GO:0005886plasma membraneIDA
molecular_function
GO:0003677DNA bindingIEA
GO:0003700sequence-specific DNA binding transcription factor activityIEA
GO:0019904protein domain specific bindingIPI
GO:0043565sequence-specific DNA bindingIEA
GO:0046983protein dimerization activityIEA

Protein-protein interaction details for NFE2L2 (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
CREBBPTwo-hybridphysical11683914
PMF1Two-hybridphysical10419538
EIF2AK3Two-hybridphysical14517290
EIF2AK3Biochemical Activityphysical14517290
KEAP1Reconstituted Complexphysical14517290
CREBBPReconstituted Complexphysical11683914
CREBBPAffinity Capture-Westernphysical11683914
MAFKReconstituted Complexphysical10747902
MAFFReconstituted Complexphysical12490281
PPARGReconstituted Complexphysical10930400
JUNAffinity Capture-Westernphysical9872330
JUNReconstituted Complexphysical9872330
KEAP1Affinity Capture-Westernphysical18757741
UBCAffinity Capture-Westernphysical18757741
KEAP1Affinity Capture-Westernphysical18417180
UBCAffinity Capture-Westernphysical18358244
UBCAffinity Capture-Westernphysical17925401
UBCReconstituted Complexphysical17636022
KEAP1Affinity Capture-Westernphysical17822677
UBCAffinity Capture-Westernphysical17822677
UBCAffinity Capture-Westernphysical17462537
KEAP1Affinity Capture-Westernphysical17462537
KEAP1Affinity Capture-Westernphysical17462537
UBCAffinity Capture-Westernphysical16000310
KEAP1Affinity Capture-Westernphysical15985429
UBCAffinity Capture-Westernphysical15983046
TRIM24Two-hybridphysical20211142
SMARCA4Affinity Capture-Westernphysical16923960
UBCAffinity Capture-Westernphysical15601839
KEAP1Affinity Capture-Westernphysical15601839
KEAP1Reconstituted Complexphysical15601839
CUL3Affinity Capture-Westernphysical15601839
UBCAffinity Capture-Westernphysical15572695
CUL3Affinity Capture-Westernphysical15367669
CUL3Affinity Capture-Westernphysical15367669
UBCAffinity Capture-Westernphysical15367669
UBCAffinity Capture-Westernphysical15282312
KEAP1Affinity Capture-Westernphysical14585973
UBCAffinity Capture-Westernphysical14585973
NCOR2Affinity Capture-Westernphysical15870285
NCOR2Affinity Capture-Westernphysical15870285
NCOR1Affinity Capture-Westernphysical15870285
NCOR2Reconstituted Complexphysical15870285
CREBBPAffinity Capture-Westernphysical18241676
CREBBPAffinity Capture-Westernphysical18241676
YY1Affinity Capture-Westernphysical20309604
YY1Affinity Capture-Westernphysical20309604
MYCAffinity Capture-Westernphysical20232342
MYCAffinity Capture-Westernphysical20232342
JUNAffinity Capture-Westernphysical20232342
KEAP1Affinity Capture-Westernphysical16790436
BACH1Co-localizationphysical15734732
BACH1Co-localizationphysical15734732
UBCAffinity Capture-Westernphysical16785233
KEAP1Affinity Capture-Westernphysical16785233
CUL3Affinity Capture-Westernphysical16785233
MAFAffinity Capture-Westernphysical16785233
UBCAffinity Capture-Westernphysical20027226
KEAP1Affinity Capture-Westernphysical20027226
PRKCDBiochemical Activityphysical19920073
PRKCABiochemical Activityphysical19920073
PRKCQBiochemical Activityphysical19920073
PRKCHBiochemical Activityphysical19920073
PRKCGBiochemical Activityphysical19920073
KEAP1Affinity Capture-Westernphysical19920073
PRKCDAffinity Capture-Westernphysical19920073
KEAP1Affinity Capture-Westernphysical19920073
KEAP1Affinity Capture-Westernphysical20486933
KEAP1Reconstituted Complexphysical20599909
KEAP1Affinity Capture-Westernphysical20599909
UBCAffinity Capture-Westernphysical22010800
CREBBPBiochemical Activityphysical19273602
CREBBPAffinity Capture-Westernphysical19273602
CREBBPReconstituted Complexphysical19273602
UBCAffinity Capture-Westernphysical19273602
KEAP1Two-hybridphysical21262351
UBCAffinity Capture-Westernphysical21262351
KEAP1Affinity Capture-Westernphysical20864537
SQSTM1Co-localizationphysical20421418
KEAP1Co-localizationphysical20421418
UBCAffinity Capture-Westernphysical20421418
KEAP1Affinity Capture-Westernphysical20421418
GADD45GIP1Affinity Capture-Westernphysical20427290
GADD45GIP1Affinity Capture-Westernphysical20427290
UBCAffinity Capture-Westernphysical20427290
KEAP1Affinity Capture-Westernphysical20463144
UBCAffinity Capture-Westernphysical20463144
CDKN1AAffinity Capture-Westernphysical19560419
UBCAffinity Capture-Westernphysical19560419
UBCReconstituted Complexphysical22215675
CUL3Biochemical Activityphysical22215675
KEAP1Reconstituted Complexphysical21383067
KEAP1Affinity Capture-Westernphysical21383067
UBCAffinity Capture-Westernphysical21383067