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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for NKX2-2 (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0003323type B pancreatic cell developmentIEA
GO:0003326pancreatic A cell fate commitmentIEA
GO:0003327type B pancreatic cell fate commitmentIEA
GO:0003329pancreatic PP cell fate commitmentIEA
GO:0007224smoothened signaling pathwayIEA
GO:0007275multicellular organismal developmentIEA
GO:0007399nervous system developmentIEA
GO:0007420brain developmentTAS
GO:0014003oligodendrocyte developmentIEA
GO:0021522spinal cord motor neuron differentiationIEA
GO:0021530spinal cord oligodendrocyte cell fate specificationIEA
GO:0031018endocrine pancreas developmentTAS
GO:0045665negative regulation of neuron differentiationIEA
GO:0045666positive regulation of neuron differentiationIEA
GO:0045944positive regulation of transcription from RNA polymerase II promoterIEA
GO:0048565digestive tract developmentIEA
GO:0048665neuron fate specificationIEA
GO:0048708astrocyte differentiationIEA
GO:0048714positive regulation of oligodendrocyte differentiationIEA
GO:0051091positive regulation of sequence-specific DNA binding transcription factor activityISS
GO:0060580ventral spinal cord interneuron fate determinationIEA
cellular_component
GO:0005634nucleusIEA
GO:0005654nucleoplasmTAS
GO:0044424intracellular partIEA
molecular_function
GO:0001159core promoter proximal region DNA bindingISS
GO:0003682chromatin bindingISS
GO:0003713transcription coactivator activityISS
GO:0008134transcription factor bindingIEA
GO:0043565sequence-specific DNA bindingIEA

Protein-protein interaction details for NKX2-2 (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
HDAC1Affinity Capture-Westernphysical15695521
SIN3AAffinity Capture-Westernphysical15695521
HDAC1Affinity Capture-Westernphysical15695521