Database of mammalian genes
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Gene
Protein
Transcript
Promoter
Expression
GO/PPI
PubMed
Cross reference
Gene Ontology information for NKX2-2 (
Homo sapiens
)
(Information is obtained from AmiGO)
ID
Term
Evidence
biological_process
GO:0003323
type B pancreatic cell development
IEA
GO:0003326
pancreatic A cell fate commitment
IEA
GO:0003327
type B pancreatic cell fate commitment
IEA
GO:0003329
pancreatic PP cell fate commitment
IEA
GO:0007224
smoothened signaling pathway
IEA
GO:0007275
multicellular organismal development
IEA
GO:0007399
nervous system development
IEA
GO:0007420
brain development
TAS
GO:0014003
oligodendrocyte development
IEA
GO:0021522
spinal cord motor neuron differentiation
IEA
GO:0021530
spinal cord oligodendrocyte cell fate specification
IEA
GO:0031018
endocrine pancreas development
TAS
GO:0045665
negative regulation of neuron differentiation
IEA
GO:0045666
positive regulation of neuron differentiation
IEA
GO:0045944
positive regulation of transcription from RNA polymerase II promoter
IEA
GO:0048565
digestive tract development
IEA
GO:0048665
neuron fate specification
IEA
GO:0048708
astrocyte differentiation
IEA
GO:0048714
positive regulation of oligodendrocyte differentiation
IEA
GO:0051091
positive regulation of sequence-specific DNA binding transcription factor activity
ISS
GO:0060580
ventral spinal cord interneuron fate determination
IEA
cellular_component
GO:0005634
nucleus
IEA
GO:0005654
nucleoplasm
TAS
GO:0044424
intracellular part
IEA
molecular_function
GO:0001159
core promoter proximal region DNA binding
ISS
GO:0003682
chromatin binding
ISS
GO:0003713
transcription coactivator activity
ISS
GO:0008134
transcription factor binding
IEA
GO:0043565
sequence-specific DNA binding
IEA
Protein-protein interaction details for NKX2-2 (
Homo sapiens
)
(Information is obtained from BioGRID)
Interacting human protein
Experiment
Type
PubMed ID
HDAC1
Affinity Capture-Western
physical
15695521
SIN3A
Affinity Capture-Western
physical
15695521
HDAC1
Affinity Capture-Western
physical
15695521