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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for OTX2 (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0001708cell fate specificationIEA
GO:0006351transcription, DNA-dependentNAS
GO:0006355regulation of transcription, DNA-dependentNAS
GO:0006461protein complex assemblyIDA
GO:0007275multicellular organismal developmentIEA
GO:0007411axon guidanceIDA
GO:0007417central nervous system developmentIEA
GO:0007492endoderm developmentIEA
GO:0008589regulation of smoothened signaling pathwayTAS
GO:0009887organ morphogenesisIEA
GO:0009952anterior/posterior pattern specificationIEA
GO:0009953dorsal/ventral pattern formationIEA
GO:0030900forebrain developmentIEA
GO:0030900forebrain developmentTAS
GO:0030901midbrain developmentIEA
GO:0030901midbrain developmentTAS
GO:0032525somite rostral/caudal axis specificationIEA
GO:0040019positive regulation of embryonic developmentISS
GO:0040036regulation of fibroblast growth factor receptor signaling pathwayTAS
GO:0042472inner ear morphogenesisIEA
GO:0042706eye photoreceptor cell fate commitmentIEA
GO:0045893positive regulation of transcription, DNA-dependentISS
GO:0045944positive regulation of transcription from RNA polymerase II promoterIDA
GO:0045944positive regulation of transcription from RNA polymerase II promoterIEA
GO:0048663neuron fate commitmentIEA
GO:0090009primitive streak formationIEA
GO:0090009primitive streak formationISS
GO:2000543positive regulation of gastrulationISS
cellular_component
GO:0005634nucleusIEA
GO:0005737cytoplasmIEA
GO:0030426growth coneIDA
GO:0043234protein complexIDA
molecular_function
GO:0001077RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcriptionIDA
GO:0003700sequence-specific DNA binding transcription factor activityIEA
GO:0003700sequence-specific DNA binding transcription factor activityNAS
GO:0005515protein bindingIPI
GO:0008190eukaryotic initiation factor 4E bindingTAS
GO:0043565sequence-specific DNA bindingIEA
GO:0046982protein heterodimerization activityIEA

Protein-protein interaction details for OTX2 (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
FOXA2Reconstituted Complexphysical12642491
OTX2Reconstituted Complexphysical10623575
FOXA2Reconstituted Complexphysical10623575
LHX1Reconstituted Complexphysical10623575