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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for P2RX7 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000187 activation of MAPK activity IEA GO:0000902 cell morphogenesis IEA GO:0001845 phagolysosome assembly IEA GO:0001916 positive regulation of T cell mediated cytotoxicity IEA GO:0001934 positive regulation of protein phosphorylation IEA GO:0002028 regulation of sodium ion transport IEA GO:0002028 regulation of sodium ion transport ISS GO:0002218 activation of innate immune response TAS GO:0006509 membrane protein ectodomain proteolysis IEA GO:0006649 phospholipid transfer to membrane IEA GO:0006811 ion transport IEA GO:0006812 cation transport IEA GO:0006816 calcium ion transport IEA GO:0006884 cell volume homeostasis IEA GO:0006900 membrane budding IEA GO:0006954 inflammatory response IEA GO:0007005 mitochondrion organization IEA GO:0007009 plasma membrane organization IEA GO:0007166 cell surface receptor linked signaling pathway IEA GO:0007166 cell surface receptor linked signaling pathway ISS GO:0009612 response to mechanical stimulus IEA GO:0009617 response to bacterium IEA GO:0010043 response to zinc ion IEA GO:0010467 gene expression IEA GO:0010524 positive regulation of calcium ion transport into cytosol IDA GO:0014049 positive regulation of glutamate secretion IEA GO:0014054 positive regulation of gamma-aminobutyric acid secretion IEA GO:0014070 response to organic cyclic compound IEA GO:0016079 synaptic vesicle exocytosis IEA GO:0016485 protein processing IEA GO:0019228 regulation of action potential in neuron IEA GO:0019233 sensory perception of pain IEA GO:0019233 sensory perception of pain ISS GO:0030501 positive regulation of bone mineralization IEA GO:0030501 positive regulation of bone mineralization ISS GO:0031668 cellular response to extracellular stimulus IEA GO:0032060 bleb assembly IEA GO:0032060 bleb assembly ISS GO:0032308 positive regulation of prostaglandin secretion IEA GO:0032496 response to lipopolysaccharide IEA GO:0032755 positive regulation of interleukin-6 production IEA GO:0032963 collagen metabolic process IEA GO:0033198 response to ATP IDA GO:0033198 response to ATP IEA GO:0034405 response to fluid shear stress IEA GO:0035590 purinergic nucleotide receptor signaling pathway IDA GO:0042098 T cell proliferation IEA GO:0042493 response to drug IEA GO:0042981 regulation of apoptosis ISS GO:0043029 T cell homeostasis IEA GO:0043065 positive regulation of apoptosis IEA GO:0043085 positive regulation of catalytic activity IEA GO:0043132 NAD transport IEA GO:0043409 negative regulation of MAPKKK cascade IEA GO:0043409 negative regulation of MAPKKK cascade ISS GO:0043410 positive regulation of MAPKKK cascade IEA GO:0044254 multicellular organismal protein catabolic process IEA GO:0045087 innate immune response TAS GO:0045332 phospholipid translocation IEA GO:0045779 negative regulation of bone resorption IEA GO:0045779 negative regulation of bone resorption ISS GO:0045919 positive regulation of cytolysis IEA GO:0045919 positive regulation of cytolysis ISS GO:0046513 ceramide biosynthetic process IEA GO:0046931 pore complex assembly IDA GO:0046931 pore complex assembly IEA GO:0048705 skeletal system morphogenesis IEA GO:0048873 homeostasis of number of cells within a tissue IEA GO:0050715 positive regulation of cytokine secretion IEA GO:0050717 positive regulation of interleukin-1 alpha secretion IEA GO:0050718 positive regulation of interleukin-1 beta secretion IDA GO:0050718 positive regulation of interleukin-1 beta secretion IEA GO:0050830 defense response to Gram-positive bacterium IEA GO:0051209 release of sequestered calcium ion into cytosol IEA GO:0051259 protein oligomerization IEA GO:0051495 positive regulation of cytoskeleton organization IEA GO:0051495 positive regulation of cytoskeleton organization ISS GO:0051592 response to calcium ion IEA GO:0051602 response to electrical stimulus IEA GO:0051709 regulation of killing of cells of other organism NAS GO:0051899 membrane depolarization IDA GO:0051899 membrane depolarization IEA GO:0051901 positive regulation of mitochondrial depolarization IEA GO:0072593 reactive oxygen species metabolic process IEA cellular_component GO:0005639 integral to nuclear inner membrane IEA GO:0005737 cytoplasm IEA GO:0005737 cytoplasm ISS GO:0005886 plasma membrane IEA GO:0005886 plasma membrane ISS GO:0005886 plasma membrane TAS GO:0005887 integral to plasma membrane IC GO:0005887 integral to plasma membrane IEA GO:0005911 cell-cell junction IEA GO:0009897 external side of plasma membrane IEA GO:0016020 membrane IDA GO:0016020 membrane IEA GO:0016021 integral to membrane IEA GO:0019717 synaptosome IEA GO:0031594 neuromuscular junction IEA GO:0032059 bleb IEA GO:0032059 bleb ISS GO:0043025 neuronal cell body IEA GO:0043195 terminal button IEA GO:0045121 membrane raft IEA molecular_function GO:0000287 magnesium ion binding IEA GO:0001530 lipopolysaccharide binding IEA GO:0001530 lipopolysaccharide binding ISS GO:0001614 purinergic nucleotide receptor activity IDA GO:0001614 purinergic nucleotide receptor activity IEA GO:0004872 receptor activity IEA GO:0004931 extracellular ATP-gated cation channel activity IDA GO:0004931 extracellular ATP-gated cation channel activity IEA GO:0005102 receptor binding IEA GO:0005102 receptor binding ISS GO:0005216 ion channel activity IEA GO:0005507 copper ion binding IEA GO:0005524 ATP binding IC GO:0005524 ATP binding IEA GO:0008270 zinc ion binding IEA GO:0015267 channel activity IEA GO:0042803 protein homodimerization activity NAS

Protein-protein interaction details for P2RX7 (Homo sapiens) (Information is obtained from BioGRID)

Not available