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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for PAX6 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0001568 blood vessel development IMP GO:0001654 eye development TAS GO:0001709 cell fate determination IEA GO:0001764 neuron migration IEA GO:0002052 positive regulation of neuroblast proliferation IEA GO:0002088 lens development in camera-type eye IEA GO:0003322 pancreatic A cell development IEA GO:0003322 pancreatic A cell development IMP GO:0006351 transcription, DNA-dependent TAS GO:0006355 regulation of transcription, DNA-dependent IEA GO:0006355 regulation of transcription, DNA-dependent TAS GO:0006366 transcription from RNA polymerase II promoter IDA GO:0006366 transcription from RNA polymerase II promoter IMP GO:0007224 smoothened signaling pathway IEA GO:0007275 multicellular organismal development IEA GO:0007411 axon guidance IEA GO:0007417 central nervous system development TAS GO:0007435 salivary gland morphogenesis IEA GO:0007601 visual perception TAS GO:0009611 response to wounding IEP GO:0009887 organ morphogenesis TAS GO:0009950 dorsal/ventral axis specification IEA GO:0010628 positive regulation of gene expression IMP GO:0016567 protein ubiquitination ISS GO:0021543 pallium development IEA GO:0021778 oligodendrocyte cell fate specification IEA GO:0021796 cerebral cortex regionalization IEA GO:0021797 forebrain anterior/posterior pattern specification IEA GO:0021798 forebrain dorsal/ventral pattern formation IEA GO:0021902 commitment of neuronal cell to specific neuron type in forebrain IEA GO:0021905 forebrain-midbrain boundary formation IEA GO:0021912 regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification IEA GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification IEA GO:0021918 regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment IEA GO:0021983 pituitary gland development IEA GO:0023019 signal transduction involved in regulation of gene expression IEA GO:0030154 cell differentiation IEA GO:0030216 keratinocyte differentiation IEA GO:0030334 regulation of cell migration IEA GO:0030858 positive regulation of epithelial cell differentiation IEA GO:0030900 forebrain development IEA GO:0032808 lacrimal gland development IEA GO:0033365 protein localization to organelle IEA GO:0042462 eye photoreceptor cell development IEA GO:0042593 glucose homeostasis IMP GO:0045665 negative regulation of neuron differentiation IEA GO:0045893 positive regulation of transcription, DNA-dependent IMP GO:0045944 positive regulation of transcription from RNA polymerase II promoter IEA GO:0048505 regulation of timing of cell differentiation IEA GO:0048663 neuron fate commitment NAS GO:0048708 astrocyte differentiation IEA GO:0050680 negative regulation of epithelial cell proliferation IEA GO:0050767 regulation of neurogenesis IEA GO:0050768 negative regulation of neurogenesis ISS GO:0061072 iris morphogenesis IMP GO:0061303 cornea development in camera-type eye IMP cellular_component GO:0000790 nuclear chromatin IDA GO:0000790 nuclear chromatin IEA GO:0005634 nucleus IDA GO:0005634 nucleus IEA GO:0005730 nucleolus IDA GO:0005737 cytoplasm IDA GO:0044424 intracellular part IEA molecular_function GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding IDA GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding IEA GO:0000981 sequence-specific DNA binding RNA polymerase II transcription factor activity IDA GO:0000981 sequence-specific DNA binding RNA polymerase II transcription factor activity IEA GO:0003677 DNA binding IEA GO:0003677 DNA binding TAS GO:0003700 sequence-specific DNA binding transcription factor activity TAS GO:0004842 ubiquitin-protein ligase activity ISS GO:0005515 protein binding IPI GO:0031625 ubiquitin protein ligase binding IEA GO:0043565 sequence-specific DNA binding IEA GO:0044212 transcription regulatory region DNA binding IEA GO:0070410 co-SMAD binding IEA GO:0070412 R-SMAD binding IEA GO:0070412 R-SMAD binding IPI

Protein-protein interaction details for PAX6 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID IPO13 Two-hybrid physical 15143176 IPO13 Two-hybrid physical 16189514 IPO13 Reconstituted Complex physical 15143176 IPO13 Affinity Capture-Western physical 15143176 SOX2 Affinity Capture-Western physical 12710953 SOX2 Affinity Capture-Western physical 12710953 CDX2 Reconstituted Complex physical 10506141 EP300 Reconstituted Complex physical 10506141 CDX2 Reconstituted Complex physical 10506141 CDX2 Affinity Capture-Western physical 10506141 CDX2 Affinity Capture-Western physical 10506141 EP300 Affinity Capture-Western physical 10506141 EP300 Affinity Capture-Western physical 10506141 RAX Phenotypic Enhancement genetic 11069920 PAX6 Reconstituted Complex physical 11069920 RAX Reconstituted Complex physical 11069920 PAX6 Affinity Capture-Western physical 11069920 RAX Affinity Capture-Western physical 11069920 SIX3 Reconstituted Complex physical 11069920 LHX2 Reconstituted Complex physical 11069920 VSX2 Reconstituted Complex physical 11069920 PKNOX1 Reconstituted Complex physical 11069920 PROX1 Reconstituted Complex physical 11069920 HOXB1 Reconstituted Complex physical 11069920 EN1 Reconstituted Complex physical 11069920 TBP Affinity Capture-Western physical 10359315 TAF1 Affinity Capture-Western physical 10359315 TBP Reconstituted Complex physical 10359315 RB1 Reconstituted Complex physical 10359315 MITF Reconstituted Complex physical 11350962 TP73 Affinity Capture-Western physical 20308539 SMARCA4 Affinity Capture-Western physical 16675956 SMARCA4 Affinity Capture-Western physical 16675956 SUMO1 Reconstituted Complex physical 21084637