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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for PDE4A (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0006198cAMP catabolic processIEA
GO:0007165signal transductionIEA
GO:0042493response to drugIEA
cellular_component
GO:0005624membrane fractionTAS
GO:0005625soluble fractionTAS
GO:0005626insoluble fractionTAS
GO:0005634nucleusIEA
GO:0005737cytoplasmIEA
GO:0005829cytosolTAS
GO:0005886plasma membraneIEA
GO:0032587ruffle membraneIEA
GO:0042995cell projectionIEA
GO:0048471perinuclear region of cytoplasmIDA
molecular_function
GO:00041153',5'-cyclic-AMP phosphodiesterase activityIEA
GO:0005515protein bindingIPI
GO:0008081phosphoric diester hydrolase activityIEA
GO:0016787hydrolase activityIEA
GO:0046872metal ion bindingIEA

Protein-protein interaction details for PDE4A (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
LYNReconstituted Complexphysical10206997
PRKAR2AAffinity Capture-Westernphysical11296225
AKAP6Affinity Capture-Westernphysical11296225
AKAP6Affinity Capture-Westernphysical11296225
PRKAR2AAffinity Capture-Westernphysical11296225
SQSTM1Affinity Capture-Westernphysical20600853
UBCAffinity Capture-Westernphysical20600853