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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for PDGFRA (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0001553 luteinization IEA GO:0001553 luteinization ISS GO:0001701 in utero embryonic development IEA GO:0001775 cell activation TAS GO:0008210 estrogen metabolic process IEA GO:0008284 positive regulation of cell proliferation IDA GO:0008284 positive regulation of cell proliferation IEA GO:0008585 female gonad development IEA GO:0009725 response to hormone stimulus IEA GO:0010035 response to inorganic substance IEA GO:0018108 peptidyl-tyrosine phosphorylation IDA GO:0023019 signal transduction involved in regulation of gene expression IEA GO:0030198 extracellular matrix organization IEA GO:0030324 lung development IEA GO:0030325 adrenal gland development IEA GO:0030335 positive regulation of cell migration IDA GO:0030539 male genitalia development IEA GO:0032355 response to estradiol stimulus IEA GO:0033327 Leydig cell differentiation IEA GO:0034097 response to cytokine stimulus IEA GO:0035790 platelet-derived growth factor receptor-alpha signaling pathway IDA GO:0042060 wound healing IEA GO:0042063 gliogenesis IEA GO:0042475 odontogenesis of dentine-containing tooth IEA GO:0045740 positive regulation of DNA replication IDA GO:0046777 protein autophosphorylation IDA GO:0048008 platelet-derived growth factor receptor signaling pathway IDA GO:0048010 vascular endothelial growth factor receptor signaling pathway IDA GO:0048146 positive regulation of fibroblast proliferation IDA GO:0048705 skeletal system morphogenesis IEA GO:0048839 inner ear development IEA GO:0055003 cardiac myofibril assembly IEA GO:0055003 cardiac myofibril assembly ISS GO:0055093 response to hyperoxia IEA GO:0060021 palate development IEA GO:0060325 face morphogenesis IEA GO:0061298 retina vasculature development in camera-type eye IEA GO:0061298 retina vasculature development in camera-type eye ISS GO:0071230 cellular response to amino acid stimulus IEA GO:0072277 metanephric glomerular capillary formation IEA GO:0072277 metanephric glomerular capillary formation ISS cellular_component GO:0005634 nucleus IEA GO:0005634 nucleus ISS GO:0005737 cytoplasm IEA GO:0005737 cytoplasm ISS GO:0005886 plasma membrane IEA GO:0005886 plasma membrane TAS GO:0005887 integral to plasma membrane IDA GO:0005887 integral to plasma membrane IEA GO:0016020 membrane IEA molecular_function GO:0000166 nucleotide binding IEA GO:0004672 protein kinase activity IEA GO:0004713 protein tyrosine kinase activity TAS GO:0004872 receptor activity IEA GO:0005018 platelet-derived growth factor alpha-receptor activity IDA GO:0005018 platelet-derived growth factor alpha-receptor activity IEA GO:0005021 vascular endothelial growth factor-activated receptor activity IDA GO:0005021 vascular endothelial growth factor-activated receptor activity IEA GO:0005161 platelet-derived growth factor receptor binding IPI GO:0005524 ATP binding IEA GO:0016772 transferase activity, transferring phosphorus-containing groups IEA GO:0019838 growth factor binding IPI GO:0042803 protein homodimerization activity IDA GO:0043548 phosphatidylinositol 3-kinase binding IEA GO:0048407 platelet-derived growth factor binding IEA GO:0048407 platelet-derived growth factor binding IPI

Protein-protein interaction details for PDGFRA (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID CBL Affinity Capture-Western physical 9234717 CBL Reconstituted Complex physical 9234717 PDGFA Reconstituted Complex physical 2544881 PDGFB Reconstituted Complex physical 2544881 PDGFC Reconstituted Complex physical 11297552 PDGFC Affinity Capture-Western physical 11297552 PDGFRB Affinity Capture-Western physical 7523122 PDGFRA Affinity Capture-Western physical 7523122 PDGFRB Reconstituted Complex physical 2542288 CRKL Affinity Capture-Western physical 9546424 CRK Affinity Capture-Western physical 9546424 GRB2 Affinity Capture-Western physical 8943348 CRK Affinity Capture-Western physical 10733900 CRK Reconstituted Complex physical 10733900 PDGFRA Biochemical Activity physical 7535778 PLCG1 Affinity Capture-Western physical 7535778 PLCG1 Reconstituted Complex physical 7535778 SLC9A3R1 Far Western physical 11046132 SLC9A3R1 Far Western physical 11046132 SLC9A3R1 Reconstituted Complex physical 11046132 SLC9A3R1 Affinity Capture-Western physical 11046132 PDGFRA Far Western physical 11046132 ITGB3 Affinity Capture-Western physical 11953315 CAV1 Affinity Capture-Western physical 10066366 CAV1 Co-fractionation physical 10066366 CAV1 Reconstituted Complex physical 10066366 CAV3 Reconstituted Complex physical 10066366 SNX6 Affinity Capture-Western physical 11279102 SNX2 Affinity Capture-Western physical 9819414 SNX4 Affinity Capture-Western physical 9819414 PTEN Affinity Capture-MS physical 15717329 UBC Affinity Capture-Western physical 21596750 GRB2 Affinity Capture-Western physical 21596750