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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for PDPK1 (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0006469negative regulation of protein kinase activityIDA
GO:0007268synaptic transmissionTAS
GO:0007596blood coagulationTAS
GO:0008286insulin receptor signaling pathwayTAS
GO:0008543fibroblast growth factor receptor signaling pathwayTAS
GO:0016310phosphorylationEXP
GO:0018107peptidyl-threonine phosphorylationIDA
GO:0030036actin cytoskeleton organizationTAS
GO:0030168platelet activationTAS
GO:0031295T cell costimulationTAS
GO:0032148activation of protein kinase B activityIDA
GO:0032869cellular response to insulin stimulusIMP
GO:0035556intracellular signal transductionIDA
GO:0048011nerve growth factor receptor signaling pathwayTAS
GO:0048015phosphatidylinositol-mediated signalingTAS
GO:0050852T cell receptor signaling pathwayTAS
GO:0090004positive regulation of establishment of protein localization in plasma membraneIMP
cellular_component
GO:0005654nucleoplasmTAS
GO:0005737cytoplasmIDA
GO:0005829cytosolTAS
GO:0005886plasma membraneIDA
GO:0005886plasma membraneTAS
molecular_function
GO:0000166nucleotide bindingIEA
GO:0004672protein kinase activityIEA
GO:0004674protein serine/threonine kinase activityIDA
GO:0004674protein serine/threonine kinase activityIEA
GO:00046763-phosphoinositide-dependent protein kinase activityIDA
GO:0005515protein bindingIPI
GO:0005524ATP bindingIEA
GO:0016301kinase activityEXP
GO:0016772transferase activity, transferring phosphorus-containing groupsIEA

Protein-protein interaction details for PDPK1 (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
PRKCZTwo-hybridphysical10764742
PRKCITwo-hybridphysical10764742
PRSS23Two-hybridphysical16169070
SLC9A3R2Affinity Capture-Westernphysical12387817
SLC9A3R2Affinity Capture-Westernphysical12387817
SGK1Reconstituted Complexphysical12387817
PRKCZTwo-hybridphysical11781095
PRKCDTwo-hybridphysical11781095
PRKCDAffinity Capture-Westernphysical11781095
PRKCZAffinity Capture-Westernphysical11781095
PKN2Affinity Capture-Westernphysical11781095
RPS6KA3Affinity Capture-Westernphysical10856237
PDPK1Biochemical Activityphysical10856237
AKT1Affinity Capture-Westernphysical11825911
PRKCBReconstituted Complexphysical11376011
PRKCZBiochemical Activityphysical9748166
PRKCZAffinity Capture-Westernphysical9748166
PRKCZAffinity Capture-Westernphysical9748166
PKN2Two-hybridphysical10764742
PKN1Two-hybridphysical10764742
PKN1Reconstituted Complexphysical10764742
PKN2Reconstituted Complexphysical10764742
PRKCZReconstituted Complexphysical10764742
PRKCIReconstituted Complexphysical10764742
YWHAQAffinity Capture-Westernphysical12177059
YWHAHAffinity Capture-Westernphysical12177059
YWHAHReconstituted Complexphysical12177059
PRKACATwo-hybridphysical10698939
PRKACAReconstituted Complexphysical10698939
AKT1Affinity Capture-Westernphysical11313365
ILKAffinity Capture-Westernphysical11313365
SGK1Reconstituted Complexphysical10357815
MAPK8Reconstituted Complexphysical10357815
PRKCZReconstituted Complexphysical10357815
SND1Affinity Capture-MSphysical20562859
G3BP1Affinity Capture-MSphysical20562859
TBL2Affinity Capture-MSphysical20562859
PA2G4Affinity Capture-MSphysical20562859
PRKCQAffinity Capture-Westernphysical15802604
PRKCQAffinity Capture-Westernphysical15802604
CARD11Affinity Capture-Westernphysical15802604
CARD11Affinity Capture-Westernphysical15802604
PEA15Two-hybridphysical21900206
C1orf93Two-hybridphysical21900206
CARD11Two-hybridphysical21900206
POLDIP2Two-hybridphysical21900206
GIT1Two-hybridphysical21900206
ZNF133Two-hybridphysical21900206
XPO7Two-hybridphysical21900206
SBF1Two-hybridphysical21900206
PNO1Two-hybridphysical21900206
DDIT4Two-hybridphysical21900206
SMARCB1Two-hybridphysical21900206
SOCS3Two-hybridphysical21900206
C2orf44Two-hybridphysical21900206
C15orf29Two-hybridphysical21900206
XRCC6Two-hybridphysical21900206
TCAPTwo-hybridphysical21900206
BLMHTwo-hybridphysical21900206
PHAXTwo-hybridphysical21900206
ZC3HC1Two-hybridphysical21900206
LUC7L2Two-hybridphysical21900206