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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for PIN1 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000413 protein peptidyl-prolyl isomerization IDA GO:0006457 protein folding IEA GO:0007049 cell cycle IEA GO:0007088 regulation of mitosis TAS GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway IDA GO:0032321 positive regulation of Rho GTPase activity IMP GO:0032480 negative regulation of type I interferon production TAS GO:0042127 regulation of cell proliferation IEA GO:0045087 innate immune response TAS GO:0051443 positive regulation of ubiquitin-protein ligase activity IDA GO:0060393 regulation of pathway-restricted SMAD protein phosphorylation IDA GO:0070373 negative regulation of ERK1 and ERK2 cascade IDA GO:2000146 negative regulation of cell motility IDA cellular_component GO:0005634 nucleus IDA GO:0005654 nucleoplasm TAS molecular_function GO:0003755 peptidyl-prolyl cis-trans isomerase activity IDA GO:0003755 peptidyl-prolyl cis-trans isomerase activity IEA GO:0005515 protein binding IPI GO:0016853 isomerase activity IEA GO:0031434 mitogen-activated protein kinase kinase binding IPI GO:0032794 GTPase activating protein binding IPI GO:0050815 phosphoserine binding IDA GO:0050816 phosphothreonine binding IDA GO:0050816 phosphothreonine binding IPI

Protein-protein interaction details for PIN1 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID TRAF2 Two-hybrid physical 16189514 TSC22D4 Two-hybrid physical 16189514 RAI1 Two-hybrid physical 16189514 GGA2 Two-hybrid physical 16189514 ZMIZ2 Two-hybrid physical 16189514 MDFI Two-hybrid physical 16189514 HNRNPC Two-hybrid physical 16189514 RBPMS Two-hybrid physical 16189514 RBBP8 Two-hybrid physical 16189514 NONO Two-hybrid physical 16189514 VHL Affinity Capture-MS physical 17353931 CTNNB1 Reconstituted Complex physical 11533658 DAB2 Affinity Capture-Western physical 12881709 DAB2 Reconstituted Complex physical 12881709 CSNK2A1 Reconstituted Complex physical 11940573 CSNK2A2 Reconstituted Complex physical 11940573 CSNK2A1 Affinity Capture-Western physical 11940573 CSNK2A2 Affinity Capture-Western physical 11940573 TOP2A Affinity Capture-Western physical 11940573 KLHL20 Two-hybrid physical 16169070 GPAA1 Two-hybrid physical 16169070 PTOV1 Two-hybrid physical 16169070 ZCCHC10 Two-hybrid physical 16169070 DDX24 Two-hybrid physical 16169070 LEPR Two-hybrid physical 16169070 SOCS3 Two-hybrid physical 16169070 WEE1 Affinity Capture-Western physical 9499405 PLK1 Affinity Capture-Western physical 9499405 CDC27 Affinity Capture-Western physical 9499405 PKMYT1 Affinity Capture-Western physical 9499405 CDC25C Affinity Capture-Western physical 9499405 WEE1 Far Western physical 9499405 PLK1 Far Western physical 9499405 CDC27 Far Western physical 9499405 CDC25C Far Western physical 9499405 PKMYT1 Far Western physical 9499405 CDC25C Affinity Capture-Western physical 9499405 PLK1 Affinity Capture-Western physical 9499405 PKMYT1 Affinity Capture-Western physical 9499405 JUN Reconstituted Complex physical 11432833 JUN Affinity Capture-Western physical 11432833 TP53 Reconstituted Complex physical 12388558 TP53 Affinity Capture-Western physical 12388558 NFATC2 Reconstituted Complex physical 11356192 MAPT Reconstituted Complex physical 10391244 TP53 Reconstituted Complex physical 12397362 TP53 Affinity Capture-Western physical 12397362 BCL2 Affinity Capture-Western physical 11326318 RAB4A Affinity Capture-Western physical 10888662 KIF20B Reconstituted Complex physical 11470801 KIF20B Affinity Capture-Western physical 11470801 KIF20B Phenotypic Suppression genetic 11470801 CDC25C Protein-peptide physical 11604498 SUPT5H Far Western physical 11575923 SUPT5H Affinity Capture-Western physical 11575923 POLR2A Affinity Capture-Western physical 10393805 MYT1 Affinity Capture-Western physical 10504341 MYT1 Reconstituted Complex physical 10504341 CDC25C Affinity Capture-Western physical 10037602 PLK1 Affinity Capture-Western physical 10037602 CDC27 Affinity Capture-Western physical 10037602 SMAD2 Reconstituted Complex physical 19122240 SMAD3 Reconstituted Complex physical 19122240 SMAD3 Affinity Capture-Western physical 19122240 SMAD2 Affinity Capture-Western physical 19122240 SMAD3 Affinity Capture-Western physical 19122240 FOXO4 Reconstituted Complex physical 18794148 FOXO4 Affinity Capture-Western physical 18794148 MCL1 Reconstituted Complex physical 17670986 MCL1 Affinity Capture-Western physical 17670986 PLK1 Reconstituted Complex physical 16118204 PLK1 Biochemical Activity physical 16118204 UBC Affinity Capture-Western physical 16118204 RARA Reconstituted Complex physical 15670742 BCLAF1 Affinity Capture-MS physical 16055720 CCNK Affinity Capture-MS physical 16055720 CDK12 Affinity Capture-MS physical 16055720 ETV6 Affinity Capture-MS physical 16055720 MED1 Affinity Capture-MS physical 16055720 THRAP3 Affinity Capture-MS physical 16055720 TLE3 Affinity Capture-MS physical 16055720 DDX17 Affinity Capture-MS physical 16055720 DDX3X Affinity Capture-MS physical 16055720 DDX5 Affinity Capture-MS physical 16055720 DHX15 Affinity Capture-MS physical 16055720 KIAA1429 Affinity Capture-MS physical 16055720 TUT1 Affinity Capture-MS physical 16055720 G3BP2 Affinity Capture-MS physical 16055720 G3BP1 Affinity Capture-MS physical 16055720 HNRNPH1 Affinity Capture-MS physical 16055720 HNRNPK Affinity Capture-MS physical 16055720 HNRNPU Affinity Capture-MS physical 16055720 EFTUD2 Affinity Capture-MS physical 16055720 NONO Affinity Capture-MS physical 16055720 PABPC1 Affinity Capture-MS physical 16055720 PRPF8 Affinity Capture-MS physical 16055720 RNPS1 Affinity Capture-MS physical 16055720 SFPQ Affinity Capture-MS physical 16055720 SRSF11 Affinity Capture-MS physical 16055720 SRRM1 Affinity Capture-MS physical 16055720 SRRM2 Affinity Capture-MS physical 16055720 U2AF2 Affinity Capture-MS physical 16055720 SNRNP200 Affinity Capture-MS physical 16055720 RPL4 Affinity Capture-MS physical 16055720 DDB1 Affinity Capture-MS physical 16055720 WRNIP1 Affinity Capture-MS physical 16055720 CDK11B Affinity Capture-MS physical 16055720 CDK11A Affinity Capture-MS physical 16055720 XRCC6 Affinity Capture-MS physical 16055720 MAP1S Affinity Capture-MS physical 16055720 AP2A1 Affinity Capture-MS physical 16055720 REPS1 Affinity Capture-MS physical 16055720 ZNF828 Affinity Capture-MS physical 16055720 PRRC1 Affinity Capture-MS physical 16055720 CAPRIN1 Affinity Capture-MS physical 16055720 TBC1D4 Affinity Capture-MS physical 16055720 TFG Affinity Capture-MS physical 16055720 HADHA Affinity Capture-MS physical 16055720 PKM2 Affinity Capture-MS physical 16055720 ADARB1 Affinity Capture-Western physical 21847096 ADARB1 Reconstituted Complex physical 21847096 AXIN1 Affinity Capture-Western physical 19131971 MYC Affinity Capture-Western physical 19131971 CDKN1B Reconstituted Complex physical 19584057 CDKN1B Affinity Capture-Western physical 19584057 CDKN1B Protein-peptide physical 19584057 DEAF1 Two-hybrid physical 21900206 TSC2 Two-hybrid physical 21900206 CASP6 Two-hybrid physical 21900206 COL11A2 Two-hybrid physical 21900206 KIF5A Two-hybrid physical 21900206 CENPB Two-hybrid physical 21900206 TP53 Two-hybrid physical 21900206 CSAD Two-hybrid physical 21900206 ATP5B Two-hybrid physical 21900206 CPNE6 Two-hybrid physical 21900206 PKM2 Two-hybrid physical 21900206 CCDC90B Two-hybrid physical 21900206 DYNC1I1 Two-hybrid physical 21900206 EIF3G Two-hybrid physical 21900206 UNC119 Two-hybrid physical 21900206 DDAH2 Two-hybrid physical 21900206 APLP1 Two-hybrid physical 21900206 CARHSP1 Two-hybrid physical 21900206 QARS Two-hybrid physical 21900206 WIZ Two-hybrid physical 21900206 MLL4 Two-hybrid physical 21900206 TRMT2A Two-hybrid physical 21900206 BAT3 Two-hybrid physical 21900206 C1orf103 Two-hybrid physical 21900206 DMPK Two-hybrid physical 21900206 CDK10 Reconstituted Complex physical 22158035 CDK10 Affinity Capture-Western physical 22158035 CDK10 Affinity Capture-Western physical 22158035 PIM1 Affinity Capture-Western physical 17297438