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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for ATP7A (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0001568 blood vessel development ISS GO:0001701 in utero embryonic development IEA GO:0001836 release of cytochrome c from mitochondria IEA GO:0001974 blood vessel remodeling ISS GO:0002082 regulation of oxidative phosphorylation ISS GO:0006568 tryptophan metabolic process ISS GO:0006570 tyrosine metabolic process IEA GO:0006584 catecholamine metabolic process ISS GO:0006754 ATP biosynthetic process IEA GO:0006825 copper ion transport IEA GO:0006825 copper ion transport IMP GO:0006878 cellular copper ion homeostasis IMP GO:0007005 mitochondrion organization ISS GO:0007626 locomotory behavior ISS GO:0008219 cell death IEA GO:0010041 response to iron(III) ion IEA GO:0010043 response to zinc ion IEA GO:0010273 detoxification of copper ion ISS GO:0010468 regulation of gene expression IEA GO:0015677 copper ion import ISS GO:0018205 peptidyl-lysine modification ISS GO:0019430 removal of superoxide radicals ISS GO:0021702 cerebellar Purkinje cell differentiation ISS GO:0021860 pyramidal neuron development ISS GO:0021954 central nervous system neuron development ISS GO:0030001 metal ion transport IEA GO:0030198 extracellular matrix organization ISS GO:0030199 collagen fibril organization ISS GO:0031069 hair follicle morphogenesis ISS GO:0034220 ion transmembrane transport TAS GO:0042093 T-helper cell differentiation ISS GO:0042414 epinephrine metabolic process ISS GO:0042415 norepinephrine metabolic process ISS GO:0042417 dopamine metabolic process ISS GO:0042421 norepinephrine biosynthetic process IEA GO:0042428 serotonin metabolic process ISS GO:0043085 positive regulation of catalytic activity ISS GO:0043473 pigmentation ISS GO:0043526 neuroprotection ISS GO:0043588 skin development ISS GO:0048251 elastic fiber assembly ISS GO:0048286 lung alveolus development ISS GO:0048553 negative regulation of metalloenzyme activity ISS GO:0048554 positive regulation of metalloenzyme activity ISS GO:0048812 neuron projection morphogenesis ISS GO:0048813 dendrite morphogenesis IEA GO:0051216 cartilage development ISS GO:0051353 positive regulation of oxidoreductase activity IDA GO:0051542 elastin biosynthetic process ISS GO:0055085 transmembrane transport TAS GO:0060003 copper ion export ISS cellular_component GO:0000299 integral to membrane of membrane fraction IEA GO:0005737 cytoplasm IEA GO:0005770 late endosome IDA GO:0005783 endoplasmic reticulum IDA GO:0005783 endoplasmic reticulum IEA GO:0005794 Golgi apparatus IDA GO:0005802 trans-Golgi network IDA GO:0005829 cytosol IEA GO:0005886 plasma membrane IDA GO:0005886 plasma membrane TAS GO:0016020 membrane IEA GO:0016021 integral to membrane IEA GO:0016323 basolateral plasma membrane IDA GO:0030140 trans-Golgi network transport vesicle IMP GO:0030141 stored secretory granule IEA GO:0031410 cytoplasmic vesicle IEA GO:0031526 brush border membrane IEA GO:0043005 neuron projection ISS GO:0043025 neuronal cell body ISS GO:0048471 perinuclear region of cytoplasm IDA molecular_function GO:0000166 nucleotide binding IEA GO:0004008 copper-exporting ATPase activity IEA GO:0004008 copper-exporting ATPase activity ISS GO:0005375 copper ion transmembrane transporter activity ISS GO:0005507 copper ion binding IDA GO:0005507 copper ion binding IEA GO:0005515 protein binding IPI GO:0005524 ATP binding IEA GO:0005524 ATP binding TAS GO:0015662 ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism IEA GO:0016532 superoxide dismutase copper chaperone activity ISS GO:0016787 hydrolase activity IEA GO:0032767 copper-dependent protein binding IPI GO:0046872 metal ion binding IEA

Protein-protein interaction details for ATP7A (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID GLRX Two-hybrid physical 16884690 GLRX Affinity Capture-Western physical 16884690 ATOX1 Two-hybrid physical 10497213 ATOX1 Reconstituted Complex physical 10497213 ATOX1 Two-hybrid physical 12679332