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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for XRN1 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay TAS GO:0000956 nuclear-transcribed mRNA catabolic process IMP GO:0006139 nucleobase-containing compound metabolic process IEA GO:0016070 RNA metabolic process TAS GO:0016071 mRNA metabolic process TAS GO:0016075 rRNA catabolic process IMP GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay TAS GO:0071028 nuclear mRNA surveillance IMP GO:0071044 histone mRNA catabolic process IMP cellular_component GO:0005622 intracellular IEA GO:0005737 cytoplasm IDA GO:0005794 Golgi apparatus IDA GO:0005829 cytosol TAS GO:0005886 plasma membrane IDA GO:0045111 intermediate filament cytoskeleton IDA molecular_function GO:0003676 nucleic acid binding IEA GO:0003677 DNA binding IEA GO:0003723 RNA binding IEA GO:0004527 exonuclease activity IEA GO:0005515 protein binding IPI GO:0008409 5'-3' exonuclease activity IEA GO:0016787 hydrolase activity IEA

Protein-protein interaction details for XRN1 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID ALDOA Two-hybrid physical 15231747 BAT3 Two-hybrid physical 15231747 SMARCD2 Two-hybrid physical 15231747 CHD4 Two-hybrid physical 15231747 PABPC4 Two-hybrid physical 15231747 AP1G2 Two-hybrid physical 15231747 LSM4 Two-hybrid physical 15231747 CCT5 Two-hybrid physical 15231747 UPF1 Affinity Capture-Western physical 14527413 UPF2 Affinity Capture-Western physical 14527413 UPF3A Affinity Capture-Western physical 14527413 MLH1 Affinity Capture-MS physical 17148452 MYC Affinity Capture-MS physical 17314511