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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for POU5F1 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0001714 endodermal cell fate specification IDA GO:0001824 blastocyst development ISS GO:0003130 BMP signaling pathway involved in heart induction IMP GO:0006351 transcription, DNA-dependent IDA GO:0006351 transcription, DNA-dependent TAS GO:0006355 regulation of transcription, DNA-dependent IDA GO:0006355 regulation of transcription, DNA-dependent TAS GO:0006366 transcription from RNA polymerase II promoter ISS GO:0007275 multicellular organismal development IEA GO:0009611 response to wounding IEP GO:0009653 anatomical structure morphogenesis TAS GO:0009786 regulation of asymmetric cell division ISS GO:0010468 regulation of gene expression IMP GO:0035019 somatic stem cell maintenance IDA GO:0035019 somatic stem cell maintenance IMP GO:0035413 positive regulation of catenin import into nucleus IDA GO:0042789 mRNA transcription from RNA polymerase II promoter ISS GO:0045944 positive regulation of transcription from RNA polymerase II promoter IDA GO:0060391 positive regulation of SMAD protein import into nucleus IDA GO:0060795 cell fate commitment involved in formation of primary germ layers IMP GO:0060913 cardiac cell fate determination IDA GO:0060965 negative regulation of gene silencing by miRNA IMP GO:0090081 regulation of heart induction by regulation of canonical Wnt receptor signaling pathway IMP GO:0090308 regulation of methylation-dependent chromatin silencing IDA cellular_component GO:0005634 nucleus IC GO:0005634 nucleus IDA GO:0005634 nucleus IEA GO:0005654 nucleoplasm IDA GO:0005667 transcription factor complex IDA GO:0005737 cytoplasm IDA GO:0005829 cytosol IDA molecular_function GO:0000981 sequence-specific DNA binding RNA polymerase II transcription factor activity ISS GO:0003677 DNA binding IDA GO:0003677 DNA binding IEA GO:0003700 sequence-specific DNA binding transcription factor activity IDA GO:0003700 sequence-specific DNA binding transcription factor activity IEA GO:0005515 protein binding IPI GO:0008134 transcription factor binding IPI GO:0031625 ubiquitin protein ligase binding IPI GO:0035198 miRNA binding IDA GO:0043565 sequence-specific DNA binding IDA GO:0043565 sequence-specific DNA binding IEA GO:0044212 transcription regulatory region DNA binding IDA

Protein-protein interaction details for POU5F1 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID SOX2 Reconstituted Complex physical 12923055 MNAT1 Reconstituted Complex physical 9368058 HMGB1 Affinity Capture-Western physical 11099378 HMGB2 Affinity Capture-Western physical 11099378 SUMO1 Affinity Capture-Western physical 17525163 SETDB1 Affinity Capture-Western physical 19884257 SETDB1 Affinity Capture-Western physical 19884257 SALL4 Affinity Capture-Western physical 19060217 RNF2 Affinity Capture-Western physical 18339675 RNF2 Affinity Capture-Western physical 18339675 WDR5 Affinity Capture-Western physical 21477851 WDR5 Co-purification physical 21477851 WDR5 Affinity Capture-Western physical 21477851 WDR5 Reconstituted Complex physical 21477851 TRIM28 Affinity Capture-Western physical 20508149 TRIM28 Affinity Capture-Western physical 20508149 UBC Affinity Capture-Western physical 17013377 NR0B1 Affinity Capture-Western physical 19528230 NR0B1 Affinity Capture-Western physical 19528230 NR0B1 Reconstituted Complex physical 19528230 NR0B1 Reconstituted Complex physical 19528230 ZNF281 Affinity Capture-Western physical 18757296 ZNF143 Co-localization physical 18687992 ZNF143 Affinity Capture-Western physical 18687992 ZNF143 Affinity Capture-Western physical 18687992 EZH2 Affinity Capture-RNA physical 21151833 EHMT2 Affinity Capture-RNA physical 21151833 KRT19 Affinity Capture-RNA physical 21151833 PPIA Affinity Capture-RNA physical 21151833 EEF2 Affinity Capture-RNA physical 21151833 CAPNS1 Affinity Capture-RNA physical 21151833 SRSF3 Affinity Capture-RNA physical 21151833 TRA2B Affinity Capture-RNA physical 21151833 RPS19 Affinity Capture-RNA physical 21151833 HIST1H1T Affinity Capture-RNA physical 21151833 EIF5B Affinity Capture-RNA physical 21151833 RPL24 Affinity Capture-RNA physical 21151833 RPS23 Affinity Capture-RNA physical 21151833 PURA Affinity Capture-RNA physical 21151833 RPL29 Affinity Capture-RNA physical 21151833 TUBB4 Affinity Capture-RNA physical 21151833 PURB Affinity Capture-RNA physical 21151833 AGR2 Affinity Capture-RNA physical 21151833 ACTA1 Affinity Capture-RNA physical 21151833 HMGB1 Affinity Capture-RNA physical 21151833 EEF1A1 Affinity Capture-RNA physical 21151833 RPL31 Affinity Capture-RNA physical 21151833 FKBP7 Affinity Capture-RNA physical 21151833 RPS25 Affinity Capture-RNA physical 21151833 TUBA1A Affinity Capture-RNA physical 21151833 RPL22 Affinity Capture-RNA physical 21151833 ACTG1 Affinity Capture-RNA physical 21151833 RPL30 Affinity Capture-RNA physical 21151833 NCL Affinity Capture-RNA physical 21151833 KRT14 Affinity Capture-RNA physical 21151833 GAPDH Affinity Capture-RNA physical 21151833 HNRNPK Affinity Capture-RNA physical 21151833 YBX1 Affinity Capture-RNA physical 21151833 KRT9 Affinity Capture-RNA physical 21151833 KRT2 Affinity Capture-RNA physical 21151833 KRT1 Affinity Capture-RNA physical 21151833 KRT10 Affinity Capture-RNA physical 21151833 NR2F2 Affinity Capture-RNA physical 21151097 POU5F1 Affinity Capture-RNA physical 21151097 NCL Affinity Capture-Luminescence physical 21048921 WWP2 Affinity Capture-Western physical 19274063 WWP2 Reconstituted Complex physical 19274063 UBC Reconstituted Complex physical 19274063 WWP2 Biochemical Activity physical 19274063 UBC Affinity Capture-Western physical 19274063 UBC Affinity Capture-Western physical 19274063