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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for FANCL (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0006281 DNA repair TAS GO:0016567 protein ubiquitination TAS cellular_component GO:0005634 nucleus IEA GO:0005654 nucleoplasm TAS GO:0005737 cytoplasm IEA GO:0043240 Fanconi anaemia nuclear complex IDA molecular_function GO:0004842 ubiquitin-protein ligase activity TAS GO:0008270 zinc ion binding IEA GO:0016874 ligase activity IEA GO:0046872 metal ion binding IEA

Protein-protein interaction details for FANCL (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID FANCA Affinity Capture-MS physical 12973351 FANCM Affinity Capture-Western physical 18285517 FANCM Affinity Capture-Western physical 20347428 FANCA Affinity Capture-Western physical 20347428 FANCA Affinity Capture-Western physical 16474167 FANCG Affinity Capture-Western physical 16474167 FANCF Affinity Capture-Western physical 16474167 UBE2W PCA physical 21229326 UBE2W PCA physical 21229326 UBE2W Reconstituted Complex physical 21229326 PCNA Affinity Capture-Western physical 20937699 PCNA Affinity Capture-Western physical 20937699 PCNA Reconstituted Complex physical 20937699 APITD1 Affinity Capture-Western physical 20347429 STRA13 Affinity Capture-Western physical 20347429 APITD1 Affinity Capture-MS physical 20347429 FANCM Affinity Capture-Western physical 20347429 FANCA Affinity Capture-Western physical 20347429 C17orf70 Affinity Capture-Western physical 20347429 FANCG Affinity Capture-Western physical 20347429 APITD1 Affinity Capture-Western physical 20347429 STRA13 Affinity Capture-Western physical 20347429 FANCG Affinity Capture-Western physical 20347429 APITD1 Co-localization physical 20347429 HES1 Two-hybrid physical 18550849 HES1 Affinity Capture-Western physical 18550849 FANCA Affinity Capture-Western physical 18550849 FANCC Affinity Capture-Western physical 18550849 HES1 Affinity Capture-MS physical 18550849 FANCA Affinity Capture-Western physical 18174376 FANCM Affinity Capture-Western physical 18174376 FANCG Affinity Capture-Western physical 18174376 C17orf70 Affinity Capture-Western physical 17396147 FANCA Affinity Capture-MS physical 17396147 FANCA Affinity Capture-Western physical 17396147 FANCB Affinity Capture-Western physical 17396147 FANCB Affinity Capture-MS physical 17396147 FANCA Affinity Capture-MS physical 17396147 C17orf70 Affinity Capture-MS physical 17396147 FANCM Affinity Capture-MS physical 17396147 C17orf70 Co-purification physical 17396147 FANCM Affinity Capture-Western physical 17289582 C19orf40 Affinity Capture-Western physical 17289582 FANCA Affinity Capture-Western physical 17289582 UBE2T Two-hybrid physical 16916645 UBE2T Affinity Capture-Western physical 16916645 FANCL Biochemical Activity physical 16916645 FANCA Affinity Capture-Western physical 16720839 FANCF Affinity Capture-Western physical 16720839 FANCC Affinity Capture-Western physical 16720839 FANCB Two-hybrid physical 16720839 FANCB Two-hybrid physical 16720839 FANCG Affinity Capture-Western physical 16720839 FANCM Affinity Capture-Western physical 16720839 FANCM Affinity Capture-MS physical 16116422 FANCM Affinity Capture-Western physical 16116422 FANCA Affinity Capture-Western physical 16116422 FANCM Affinity Capture-Western physical 16116422 FANCL Affinity Capture-MS physical 17396147 FANCA Affinity Capture-Western physical 21975120